89
Views
120
CrossRef citations to date
0
Altmetric
Research Article

Molybdenum Hydroxylases as Drug-Metabolizing Enzymes

Pages 119-156 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (18)

Narges Cheshmazar, Siavoush Dastmalchi, Mineko Terao, Enrico Garattini & Maryam Hamzeh-Mivehroud. (2019) Aldehyde oxidase at the crossroad of metabolism and preclinical screening. Drug Metabolism Reviews 51:4, pages 428-452.
Read now
Tomoyuki Isobe, Masayuki Ohta, Yoshio Kaneko & Hiroyuki Kawai. (2016) Species differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase. Xenobiotica 46:7, pages 579-590.
Read now
Chiaki Tanoue, Kazumi Sugihara, Naoto Uramaru, Yoshitaka Tayama, Yoko Watanabe, Toru Horie, Shigeru Ohta & Shigeyuki Kitamura. (2013) Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes. Xenobiotica 43:11, pages 956-962.
Read now
Antje Havemeyer, Juliane Lang & Bernd Clement. (2011) The fourth mammalian molybdenum enzyme mARC: current state of research. Drug Metabolism Reviews 43:4, pages 524-539.
Read now
M. Adachi, K. Itoh, H. Abe & Y. Tanaka. (2008) Heredity mode of genetic polymorphism in aldehyde oxidase activity in Donryu strain rats. Xenobiotica 38:1, pages 98-105.
Read now
K. Itoh, H. Maruyama, M. Adachi, K. Hoshino, N. Watanabe & Y. Tanaka. (2007) Lack of dimer formation ability in rat strains with low aldehyde oxidase activity. Xenobiotica 37:7, pages 709-716.
Read now
K. Itoh, M. Yamamura, S. Muramatsu, K. Hoshino, A. Masubuchi, T. Sasaki & Y. Tanaka. (2005) Stereospecific oxidation of the (S)-enantiomer of RS-8359, a selective and reversible monoamine oxidase A (MAO-A) inhibitor, by aldehyde oxidase. Xenobiotica 35:6, pages 561-573.
Read now
Roger Harrison. (2004) Physiological Roles of Xanthine Oxidoreductase. Drug Metabolism Reviews 36:2, pages 363-375.
Read now
K. Takekawa, K. Sugihara, S. Kitamura & S. Ohta. (2001) Enzymatic and non-enzymatic reduction of brucine N -oxide by aldehyde oxidase and catalase. Xenobiotica 31:11, pages 769-782.
Read now
N. E. Austin, S. J. Baldwin, L. Cutler, N. Deeks, P. J. Kelly, M. Nash, C. E. Shardlow, G. Stemp, K. Thewlis, A. Ayrton & P. Jeffrey. (2001) Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase. Xenobiotica 31:8-9, pages 677-686.
Read now
A. A. Acheampong, D-S. Chien, S. Lam, S. Vekich, A. Breau, J. Usansky, D. Harcourt, S. A. Munk, H. Nguyen, M. Garst & D. Tang-Liu. (1996) Characterization of brimonidine metabolism with rat, rabbit, dog, monkey and human liver fractions and rabbit liver aldehyde oxidase. Xenobiotica 26:10, pages 1035-1055.
Read now
M. Strolin Benedetti & P. Dostert. (1994) Contribution of Amine Oxidases to the Metabolism of Xenobiotics. Drug Metabolism Reviews 26:3, pages 507-535.
Read now
K. Lavrijsen, J. Van Houdt, D. Van Dyck, J. Hendrickx, M. Bockx, R. Hurkmans, W. Meuldermans, L. Le Jeune, W. Lauwers & J. Heykants. (1992) Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes. Xenobiotica 22:7, pages 815-836.
Read now
Walter G. Levine. (1991) Metabolism of AZO Dyes: Implication for Detoxication and Activation. Drug Metabolism Reviews 23:3-4, pages 253-309.
Read now
C. Johnson, C. Beedham & J. G. P. Stell. (1987) Reaction of 1-amino- and 1-chlorophthalazine with mammalian molybdenum hydroxylases in vitro. Xenobiotica 17:1, pages 17-24.
Read now
A. Assandri, G. Tarzia, E. Bellasio, R. Ciabatti, G. Tuan, P. Ferrari, L. Zerilli, M. Lanfranchi & G. Pelizzi. (1987) Metabolic oxidation of the pyrrole ring: structure and origin of some urinary metabolites of the anti-hypertensive pyrrolylpyridazinamine, mopidralazine.: III: Studies with the 13C-labelled drug. Xenobiotica 17:5, pages 559-573.
Read now

Articles from other publishers (102)

Víctor Toro-Román, María Concepción Robles-Gil, Diego Muñoz, Ignacio Bartolomé, Jesús Siquier-Coll & Marcos Maynar-Mariño. (2022) Extracellular and Intracellular Concentrations of Molybdenum and Zinc in Soccer Players: Sex Differences. Biology 11:12, pages 1710.
Crossref
Slobodan P. Rendić, Rachel D. Crouch & F. Peter Guengerich. (2022) Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions. Archives of Toxicology 96:8, pages 2145-2246.
Crossref
Mohamed Hamed, Hamdy A. M. Soliman, Zainab Eid, Yahya Al Naggar & Alaa El-Din H. Sayed. (2022) Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus). Frontiers in Environmental Science 10.
Crossref
Tatsuki FukamiTsuyoshi Yokoi & Miki Nakajima. (2022) Non-P450 Drug-Metabolizing Enzymes: Contribution to Drug Disposition, Toxicity, and Development. Annual Review of Pharmacology and Toxicology 62:1, pages 405-425.
Crossref
Alejandra Gomez, Mahesh Narayan, Lijuan Zhao, Xiaorong Jia, Ricardo A. Bernal, Martha L. Lopez-Moreno & Jose R. Peralta-Videa. (2021) Effects of nano-enabled agricultural strategies on food quality: Current knowledge and future research needs. Journal of Hazardous Materials 401, pages 123385.
Crossref
Erickson M. Paragas, Kanika Choughule, Jeffrey P. Jones & John T. Barr. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 257 284 .
Rupam Dinda, Arpita Panda, Atanu Banerjee, Monalisa Mohanty, Sagarika Pasayat & Edward R.T. Tiekink. (2020) Investigation of DNA interaction and antiproliferative activity of mixed ligand dioxidomolybdenum(VI) complexes incorporating ONO donor aroylhydrazone ligands. Polyhedron 183, pages 114533.
Crossref
Chang-Hwei ChenChang-Hwei Chen. 2020. Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense. Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense 59 70 .
Deepak Dalvie & Li Di. (2019) Aldehyde oxidase and its role as a drug metabolizing enzyme. Pharmacology & Therapeutics 201, pages 137-180.
Crossref
Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio & Fatemeh Akhlaghi. (2019) Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach. Drug Metabolism and Disposition 47:8, pages 874-882.
Crossref
Yuanyuan Zhou, Yeon Jung Choi, Eunyeong Kim, Mun Hwan Oh, Hee Jae ShinSang Kyum Kim & Kiho Lee. (2018) Pharmacokinetics and Metabolism of Streptochlorin and Its Synthetic Derivative, 5-Hydroxy-2′-isobutyl Streptochlorin, in Mice. Biological and Pharmaceutical Bulletin 41:3, pages 326-337.
Crossref
Rachel D. Crouch, Anna L. Blobaum, Andrew S. Felts, P. Jeffrey Conn & Craig W. Lindsley. (2017) Species-Specific Involvement of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of the Pyrimidine-Containing mGlu 5 -Negative Allosteric Modulator VU0424238 (Auglurant) . Drug Metabolism and Disposition 45:12, pages 1245-1259.
Crossref
Maryam Hamzeh-Mivehroud, Seifullah Rahmani, Mohammad-Reza Rashidi & Siavoush Dastmalchi. (2016) Structural features of guinea pig aldehyde oxidase inhibitory activities of flavonoids explored using QSAR and molecular modeling studies. Medicinal Chemistry Research 25:12, pages 2773-2786.
Crossref
T. Bohnert, A. Patel, I. Templeton, Y. Chen, C. Lu, G. Lai, L. Leung, S. Tse, H. J. Einolf, Y.-H. Wang, M. Sinz, R. Stearns, R. Walsky, W. Geng, S. Sudsakorn, D. Moore, L. He, J. Wahlstrom, J. Keirns, R. Narayanan, D. Lang & X. Yang. (2016) Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions--an Industry Perspective. Drug Metabolism and Disposition 44:8, pages 1399-1423.
Crossref
A. Foti, T. Hartmann, C. Coelho, T. Santos-Silva, M. J. Romao & S. Leimkuhler. (2016) Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms. Drug Metabolism and Disposition 44:8, pages 1277-1285.
Crossref
Seigo Sanoh, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura & Shigeru Ohta. (2015) Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy. Drug Metabolism and Pharmacokinetics 30:1, pages 52-63.
Crossref
Sheraz A. K. Tanoli, Nazish U. Tanoli, Saman Usmani, Zaheer-Ul-Haq & Antonio G. Ferreira. (2013) The exploration of interaction studies of smaller size, mostly ignored yet intrinsically inestimable molecules towards BSA; An example of STD and DOSY NMR. Central European Journal of Chemistry 12:3, pages 332-340.
Crossref
Beatrice Bechi, Susanne Herter, Shane McKenna, Christopher Riley, Silke Leimk?hler, Nicholas J. Turner & Andrew J. Carnell. (2014) Catalytic bio?chemo and bio?bio tandem oxidation reactions for amide and carboxylic acid synthesis. Green Chem. 16:10, pages 4524-4529.
Crossref
Chigang Chen, Guyue Cheng, Haihong Hao, Menghong Dai, Xu Wang, Lingli Huang, Zhenli Liu & Zonghui Yuan. (2013) Mechanism of Porcine Liver Xanthine Oxidoreductase Mediated N-Oxide Reduction of Cyadox as Revealed by Docking and Mutagenesis Studies. PLoS ONE 8:9, pages e73912.
Crossref
Chiaki Tanoue, Kazumi Sugihara, Naoto Uramaru, Yoko Watanabe, Yoshitaka Tayama, Shigeru Ohta & Shigeyuki Kitamura. (2013) Strain Difference of Oxidative Metabolism of the Sedative-hypnotic Zaleplon by Aldehyde Oxidase and Cytochrome P450 In Vivo and In Vitro in Rats. Drug Metabolism and Pharmacokinetics 28:3, pages 269-273.
Crossref
Shin'ichi Yoshihara. (2013) A Memoir of My Researches on Xenobiotic Metabolism for 48 Years<br/>—Researches on Kanemi Yusho and Endocrine Disrupting Chemicals—薬毒物代謝研究48年を振り返って<br/>—カネミ油症事件から環境ホルモン問題まで—. YAKUGAKU ZASSHI 133:7, pages 747-772.
Crossref
Vinod K. Arora, Thomas Philip, Stella Huang & Yue-Zhong Shu. (2012) A Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde Oxidase. Drug Metabolism and Disposition 40:9, pages 1668-1676.
Crossref
Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang & Ping Kang. (2012) Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide. Drug Metabolism and Disposition 40:8, pages 1575-1587.
Crossref
Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones & Silke Leimkühler. (2012) The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase. Drug Metabolism and Disposition 40:5, pages 856-864.
Crossref
Yoshitaka Tayama, Kazumi Sugihara, Seigo Sanoh, Katsushi Miyake, Shigeyuki Kitamura & Shigeru Ohta. (2012) Developmental Changes of Aldehyde Oxidase Activity and Protein Expression in Human Liver Cytosol. Drug Metabolism and Pharmacokinetics 27:5, pages 543-547.
Crossref
Chang-Hwei ChenChang-Hwei Chen. 2012. Activation and Detoxification Enzymes. Activation and Detoxification Enzymes 137 144 .
Raman Sharma, Heather Eng, Gregory S. Walker, Gabriela Barreiro, Antonia F. Stepan, Kim F. McClure, Angela Wolford, Paul D. Bonin, Peter Cornelius & Amit S. Kalgutkar. (2011) Oxidative Metabolism of a Quinoxaline Derivative by Xanthine Oxidase in Rodent Plasma. Chemical Research in Toxicology 24:12, pages 2207-2216.
Crossref
. (2011) Scientific Opinion on Flavouring Group Evaluation 17, Revision 3 (FGE.17Rev3): Pyrazine derivatives from chemical group 24. EFSA Journal 9:11.
Crossref
. (2011) Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24. EFSA Journal 9:5.
Crossref
C Beedham. (1986) Similarity in the aldehyde oxidases from guinea-pig liver and polymorphonuclear leucocytes. Journal of Pharmacy and Pharmacology 38:1, pages 57-58.
Crossref
X Zhang, H-H Liu, P Weller, M Zheng, W Tao, J Wang, G Liao, M Monshouwer & G Peltz. (2010) In silico and in vitro pharmacogenetics: aldehyde oxidase rapidly metabolizes a p38 kinase inhibitor. The Pharmacogenomics Journal 11:1, pages 15-24.
Crossref
Yoshitaka Tayama, Kazumi Sugihara, Seigo Sanoh, Katsushi Miyake, Shushi Morita, Shigeyuki Kitamura & Shigeru Ohta. (2011) Effect of Tea Beverages on Aldehyde Oxidase Activity. Drug Metabolism and Pharmacokinetics 26:1, pages 94-101.
Crossref
David C. Pryde, Deepak Dalvie, Qiyue Hu, Peter Jones, R. Scott Obach & Thien-Duc Tran. (2010) Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery. Journal of Medicinal Chemistry 53:24, pages 8441-8460.
Crossref
S.O. Asagba, G.E. Eriyamremu, B.O. George & I. Okoro. (2010) Biochemical Indices of Severity in Human Malaria. Journal of Medical Sciences(Faisalabad) 10:4, pages 87-92.
Crossref
Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe & Yorihisa Tanaka. (2010) A Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1. Drug Metabolism and Disposition 38:2, pages 302-307.
Crossref
Kunio ITOH. (2009) Individual and Strain Difference of Aldehyde Oxidase in RatAldehyde Oxidaseの機能解析—個体差・系統差を中心として—. YAKUGAKU ZASSHI 129:12, pages 1487-1493.
Crossref
Ping Liu, Sun Liang, Ben-Jie Wang & Rui-Chen Guo. (2009) Construction of expression system of rabbit aldehyde oxidase cDNA for the clarification of species differences. European Journal of Drug Metabolism and Pharmacokinetics 34:3-4, pages 205-211.
Crossref
Kunio Itoh, Tasuku Asakawa, Kouichi Hoshino, Mayuko Adachi, Kensuke Fukiya, Nobuaki WatanabeYorihisa Tanaka. (2009) Functional Analysis of Aldehyde Oxidase Using Expressed Chimeric Enzyme between Monkey and Rat. Biological and Pharmaceutical Bulletin 32:1, pages 31-35.
Crossref
Luca Ronconi & Peter J. Sadler. (2008) Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry. Coordination Chemistry Reviews 252:21-22, pages 2239-2277.
Crossref
. (2008) Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC). EFSA Journal 6:9, pages 812.
Crossref
Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie & Shigeru Ohta. (2008) Aldehyde Oxidase-Catalyzed Metabolism of N 1 -Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver . Drug Metabolism and Disposition 36:7, pages 1202-1205.
Crossref
Tasuku Asakawa, Kunio Itoh, Mayuko Adachi, Kouichi Hoshino, Nobuaki WatanabeYorihisa Tanaka. (2008) Properties of 130 kDa Subunit of Monkey Aldehyde Oxidase. Biological and Pharmaceutical Bulletin 31:3, pages 380-385.
Crossref
Mayuko Adachi, Kunio Itoh, Akiko Masubuchi, Nobuaki Watanabe & Yorihisa Tanaka. (2007) Construction and Expression of Mutant cDNAs Responsible for Genetic Polymorphism in Aldehyde Oxidase in Donryu Strain Rats. BMB Reports 40:6, pages 1021-1027.
Crossref
Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe & Yorihisa Tanaka. (2007) Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution. Drug Metabolism and Disposition 35:10, pages 1860-1864.
Crossref
Jack Uetrecht & William Trager. 2007. Drug Metabolism. Drug Metabolism 33 108 .
Kunio Itoh, Akiko Masubuchi, Takamitsu Sasaki, Mayuko Adachi, Nobuaki Watanabe, Kiyoshi Nagata, Yasushi Yamazoe, Masahiro Hiratsuka, Michinao Mizugaki & Yorihisa Tanaka. (2007) Genetic Polymorphism of Aldehyde Oxidase in Donryu Rats. Drug Metabolism and Disposition 35:5, pages 734-739.
Crossref
Y Tayama, K Miyake, K Sugihara, S Kitamura, M Kobayashi, S Morita, S Ohta & K Kihira. (2007) Developmental Changes of Aldehyde Oxidase Activity in Young Japanese Children. Clinical Pharmacology & Therapeutics 81:4, pages 567-572.
Crossref
Bernard Testa & Stefanie D. Krämer. (2007) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 4:3, pages 257-405.
Crossref
Yoshitaka Tayama, Aya Moriyasu, Kazumi Sugihara, Shigeru Ohta & Shigeyuki Kitamura. (2007) Developmental Changes of Aldehyde Oxidase in Postnatal Rat Liver. Drug Metabolism and Pharmacokinetics 22:2, pages 119-124.
Crossref
Kouichi Hoshino, Kunio Itoh, Akiko Masubuchi, Mayuko Adachi, Tasuku Asakawa, Nobuaki WatanabeToshiyuki KosakaYorihisa Tanaka. (2007) Cloning, Expression, and Characterization of Male Cynomolgus Monkey Liver Aldehyde Oxidase. Biological and Pharmaceutical Bulletin 30:7, pages 1191-1198.
Crossref
W.F. Trager. 2007. Comprehensive Medicinal Chemistry II. Comprehensive Medicinal Chemistry II 87 132 .
Takamitsu Sasaki, Akiko Masubuchi, Mayumi Yamamura, Nobuaki Watanabe, Masahiro Hiratsuka, Michinao Mizugaki, Kunio Itoh & Yorihisa Tanaka. (2006) Rat strain differences in stereospecific 2‐oxidation of RS‐8359, a reversible and selective MAO‐A inhibitor, by aldehyde oxidase. Biopharmaceutics & Drug Disposition 27:5, pages 247-255.
Crossref
Kunio Itoh, Mayumi Yamamura, Wataru Takasaki, Takamitsu Sasaki, Akiko Masubuchi & Yorihisa Tanaka. (2006) Species differences in enantioselective 2-oxidations of RS-8359, a selective and reversible MAO-A inhibitor, and cinchona alkaloids by aldehyde oxidase. Biopharmaceutics & Drug Disposition 27:3, pages 133-139.
Crossref
. (2006) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Comm. EFSA Journal 4:1, pages 295.
Crossref
Shigeyuki Kitamura, Kazumi Sugihara & Shigeru Ohta. (2006) Drug-Metabolizing Ability of Molybdenum Hydroxylases. Drug Metabolism and Pharmacokinetics 21:2, pages 83-98.
Crossref
Aya Moriyasu, Kazumi Sugihara, Keiko Nakatani, Shigeru Ohta & Shigeyuki Kitamura. (2006) In vivo-In vitro Relationship of Methotrexate 7-Hydroxylation by Aldehyde Oxidase in Four Different Strain Rats. Drug Metabolism and Pharmacokinetics 21:6, pages 485-491.
Crossref
Forrest Nielsen. 2005. Sports Nutrition. Sports Nutrition 287 320 .
Osamu Ueda, Kazumi Sugihara, Shigeru Ohta & Shigeyuki Kitamura. (2005) INVOLVEMENT OF MOLYBDENUM HYDROXYLASES IN REDUCTIVE METABOLISM OF NITRO POLYCYCLIC AROMATIC HYDROCARBONS IN MAMMALIAN SKIN. Drug Metabolism and Disposition 33:9, pages 1312-1318.
Crossref
. 2005. Drug Metabolism. Drug Metabolism 171 208 .
A.K. Cowan & C.H. Bornman. (2004) Metabolic control of avocado fruit growth: 3-hydroxy-3-methylglutaryl coenzyme a reductase, active oxygen species and the role of C7 sugars. South African Journal of Botany 70:1, pages 75-82.
Crossref
Dieter Lang & Amit Kalgutkar. 2003. Drug Metabolizing Enzymes. Drug Metabolizing Enzymes 483 539 .
Asma Khatun, Chandan Kumar Saha .Zabun Naher .Shirin Mahbub .Abu Bakar Siddique .Shahana Bilkis .. (2003) Plant Regeneration from the Cotyledonds of Tossa Jute (Corchorus olitorius L.). Biotechnology(Faisalabad) 2:3, pages 206-213.
Crossref
Asad-ur-Rehman .Sikander Ali .Ikram-ul-Haq .. (2003) Selection of Fermentation for Citric Acid in Bioreactor. Biotechnology(Faisalabad) 2:3, pages 178-184.
Crossref
Miquel Salva, Josep M. Jansat, Antonio Martinez-Tobed & Jose M. Palacios. (2003) Identification of the Human Liver Enzymes Involved in the Metabolism of the Antimigraine Agent Almotriptan. Drug Metabolism and Disposition 31:4, pages 404-411.
Crossref
Donald J. AbrahamBernard Testa & William Soine. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 431 498 .
Marcin Hoffmann & Jacek Rychlewski. 2002. Quantum Systems in Chemistry and Physics Volume 2. Quantum Systems in Chemistry and Physics Volume 2 233 240 .
Daniel L. Gilbert & Carol A. ColtonDale A. Parks, Kelly A. Skinner, Sidhartha Tan & Henry B. Skinner. 2002. Reactive Oxygen Species in Biological Systems. Reactive Oxygen Species in Biological Systems 397 420 .
Kazumi Sugihara, Shigeyuki Kitamura, Tuyoshi Yamada, Shigeru Ohta, Keisuke Yamashita, Mineo Yasuda & Yoshiaki Fujii-Kuriyama. (2001) Aryl Hydrocarbon Receptor (AhR)-Mediated Induction of Xanthine Oxidase/Xanthine Dehydrogenase Activity by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Biochemical and Biophysical Research Communications 281:5, pages 1093-1099.
Crossref
Shigeyuki KITAMURA, Keiko NAKATANI, Koji OHASHI, Kazumi SUGIHARA, Ryuji HOSOKAWA, Yasumasa AKAGAWA & Shigeru OHTA. (2001) Extremely High Drug-Reductase Activity Based on Aldehyde Oxidase in Monkey Liver.. Biological and Pharmaceutical Bulletin 24:7, pages 856-859.
Crossref
Forrest H. Nielsen. 2008. The Cambridge World History of Food. The Cambridge World History of Food 856 868 .
. 2008. The Cambridge World History of Food. The Cambridge World History of Food 739 740 .
Kazumi Sugihara, Yasuko Katsuma, Shigeyuki Kitamura, Shigeru Ohta, Morioki Fujitani & Hideaki Shintani. (2000) Cynomolgus monkey liver aldehyde oxidase: extremely high oxidase activity and an attempt at purification. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 126:1, pages 53-60.
Crossref
Gonzalo J. Diaz & E. James Squires. (2000) Role of Aldehyde Oxidase in the Hepatic in Vitro Metabolism of 3-Methylindole in Pigs. Journal of Agricultural and Food Chemistry 48:3, pages 833-837.
Crossref
Allan Rettie & Michael Fisher. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism 131 151 .
Shin'ichi Yoshihara & Shigeru Ohta. (1998) Involvement of Hepatic Aldehyde Oxidase in Conversion of 1-Methyl-4-phenyl-2,3-dihydropyridinium (MPDP+) to 1-Methyl-4-phenyl-5,6-dihydro-2-pyridone. Archives of Biochemistry and Biophysics 360:1, pages 93-98.
Crossref
Dale A Parks, Kelly A Skinner, Henry B Skinner & Sidhartha Tan. (1998) Multiple organ dysfunction syndrome: Role of xanthine oxidase and nitric oxide. Pathophysiology 5:1, pages 49-66.
Crossref
Susanne Fetzner, Barbara Tshisuaka, Franz Lingens, Reinhard Kappl & Jürgen Hüttermann. (1998) Der bakterielle Abbau von Chinolin und seinen Derivaten – Abbauwege und Biokatalysatoren. Angewandte Chemie 110:5, pages 596-617.
Crossref
M. Strolin Benedetti & K. F. Tipton. 1998. MAO — The Mother of all Amine Oxidases. MAO — The Mother of all Amine Oxidases 149 171 .
Neal Castagnoli,, John M. Rimoldi, Jeff Bloomquist & Kay P. Castagnoli. (1997) Potential Metabolic Bioactivation Pathways Involving Cyclic Tertiary Amines and Azaarenes. Chemical Research in Toxicology 10:9, pages 924-940.
Crossref
Shin'ichi Yoshihara & Kiyoshi Tatsumi. (1997) Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase. Biochemical Pharmacology 53:8, pages 1099-1105.
Crossref
Ge Lin, Ka-Wing Chu, Lyaquatali A. Damani & Edward M. Hawes. (1996) Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs. Journal of Pharmaceutical and Biomedical Analysis 14:6, pages 727-738.
Crossref
Ingrid Stephan, Barbara Tshisuaka, Susanne Fetzner & Franz Lingens. (2004) Quinaldine 4‐Oxidase from Arthrobacter sp. Rü61a, a Versatile Procaryotic Molybdenum‐Containing Hydroxylase Active towards N‐Containing Heterocyclic Compounds and Aromatic Aldehydes . European Journal of Biochemistry 236:1, pages 155-162.
Crossref
Sandip K. Roy, Kenneth R. Korzekwa, Frank J. Gonzalez, Robert C. Moschel & M.Eileen Dolan. (1995) Human liver oxidative metabolism of O6-benzylguanine. Biochemical Pharmacology 50:9, pages 1385-1389.
Crossref
A. Kooij. (1994) A re-evaluation of the tissue distribution and physiology of xanthine oxidoreductase. The Histochemical Journal 26:12, pages 889-915.
Crossref
A.David Rodrigues. (1994) Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro. Biochemical Pharmacology 48:1, pages 199-200.
Crossref
Keun Huh, Uk-Seob Shin, Jong-Won Choi & Sang-Il Lee. (1994) Effect of sex hormones on lipid peroxidation in rat liver. Archives of Pharmacal Research 17:2, pages 109-114.
Crossref
Vishwanath M. Sardesai. (2016) Molybdenum: An Essential Trace Element. Nutrition in Clinical Practice 8:6, pages 277-281.
Crossref
Iain G.C. Robertson & Tony J. Bland. (1993) Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide. Biochemical Pharmacology 45:10, pages 2159-2162.
Crossref
Ann K. Daly, Suzanne Cholerton, Wendy Gregory & Jeffrey R. Idle. (1993) Metabolic polymorphisms. Pharmacology & Therapeutics 57:2-3, pages 129-160.
Crossref
Rafael Radi, Sidhartha Tan, Eugenio Prodanov, Roy A. Evans & Dale A. Parks. (1992) Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1122:2, pages 178-182.
Crossref
Albert M. Stoddart & Walter G. Levine. (1992) Azoreductase activity by purified rabbit liver aldehyde oxidase. Biochemical Pharmacology 43:10, pages 2227-2235.
Crossref
Martina Blaschke, Annette Kretzer, Christine Schäfer, Matthias Nagel & Jan R. Andreesen. (1991) Molybdenum-dependent degradation of quinoline by Pseudomonas putida Chin IK and other aerobic bacteria. Archives of Microbiology 155:2, pages 164-169.
Crossref
K KoenigJ R Andreesen. (1990) Xanthine dehydrogenase and 2-furoyl-coenzyme A dehydrogenase from Pseudomonas putida Fu1: two molybdenum-containing dehydrogenases of novel structural composition. Journal of Bacteriology 172:10, pages 5999-6009.
Crossref
Sebastian Reiter, H.Anne Simmonds, Nepomuk Zöllner, Siegmund L. Braun & Maximilian Knedel. (1990) Demonstration of a combined deficiency of xanthine oxidase and aldehyde oxidase in xanthinuric patients not forming oxipurinol. Clinica Chimica Acta 187:3, pages 221-234.
Crossref
Inka Siegmund, Kerstein Koenig & Jan R. Andreesen. (1990) Molybdenum involvement in aerobic degradation of picolinic acid by Arthrobacter picolinophilus . FEMS Microbiology Letters 67:3, pages 281-284.
Crossref
A.J. Warne & J.G.P. Stell. (1990) Purification of aldehyde oxidase from liver by affinity chromatography and FPLC. Journal of Pharmaceutical and Biomedical Analysis 8:8-12, pages 1015-1019.
Crossref
Christine Beedham, David J. Padwick, Youseff Al-Tayib & John A. Smith. (1989) Diurnal variation and melatonin induction of hepatic molybdenum hydroxylase activity in the guinea-pig. Biochemical Pharmacology 38:9, pages 1459-1464.
Crossref
L.Λ. Damani. (1988) CHEMICAL REACTIVITY CONSIDERATIONS IN THE METABOLISM OF N-HETEROAROMATICS. Drug Metabolism and Drug Interactions 6:2.
Crossref
C. Beedham, S. E. Bruce & D. J. Rance. (1987) Tissue distribution of the molybdenum hydroxylases, aldehyde. European Journal of Drug Metabolism and Pharmacokinetics 12:4, pages 303-306.
Crossref
Christine Beedham. 1987. 85 127 .
R.Bruce Banks & Stewart D. Barnett. (1986) Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase. Biochemical and Biophysical Research Communications 140:2, pages 609-615.
Crossref
Christine Johnson, Christine Stubley-Beedham, J. Godfrey & P. Stell. (1985) Hydralazine: A potent inhibitor of aldehyde oxidase activity in vitro and in vivo. Biochemical Pharmacology 34:24, pages 4251-4256.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.