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Hemoglobin
international journal for hemoglobin research
Volume 19, 1995 - Issue 6
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Original Article

The Frequency of 14 β-Thalassemia Mutations in the Arab Populations

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Pages 353-360 | Received 15 Jun 1994, Accepted 07 Aug 1995, Published online: 07 Jul 2009

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Aisha Moeen Khan, Asma Mohammed Al-Sulaiti, Salma Younes, Mohamed Yassin & Hatem Zayed. (2021) The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review. Expert Review of Hematology 14:1, pages 109-122.
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Hossam Murad, Faten Moasses, Amir Dabboul, Yasser Mukhalalaty, Ahmad Omar Bakoor, Walid Al-Achkar & Rami A. Jarjour. (2018) Geographical distribution of β-globin gene mutations in Syria. Hematology 23:9, pages 697-704.
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Masoumeh Jalilian, Farid Azizi Jalilian, Leila Ahmadi, Razieh Amini, Hossein Esfehani, Maryam Sosanian, Bahareh Rabbani, Majid Maleki & Nejat Mahdieh. (2017) The Frequency of HBB Mutations Among β-Thalassemia Patients in Hamadan Province, Iran. Hemoglobin 41:1, pages 61-64.
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Suha M. Hassan, Cornelis L. Harteveld, Egbert Bakker & Piero C. Giordano. (2015) Broader Spectrum of β-Thalassemia Mutations in Oman: Regional Distribution and Comparison with Neighboring Countries. Hemoglobin 39:2, pages 107-110.
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Hossam Murad, Faten Moassas, Rami Jarjour, Yasser Mukhalalaty & Walid Al-Achkar. (2014) Prenatal Molecular Diagnosis of β-Thalassemia and Sickle Cell Anemia in the Syrian Population. Hemoglobin 38:6, pages 390-393.
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Rami A. Jarjour, Hossam Murad, Faten Moasses & Walid Al-Achkar. (2014) Molecular Update of β-Thalassemia Mutations in the Syrian Population: Identification of Rare β-Thalassemia Mutations. Hemoglobin 38:4, pages 272-276.
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Adel M. Abuzenadah, Ibtessam M. Ramzi Hussein, Ghazi A. Damanhouri, Faten M. A-Sayes, Mamdouh A. Gari, Adeel G. Chaudhary, Galila F. Zaher, Asma’a Al-Attas & Mohammad H. Al-Qahtani. (2011) Molecular Basis of β-Thalassemia in the Western Province of Saudi Arabia: Identification of Rare β-Thalassemia Mutations. Hemoglobin 35:4, pages 346-357.
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Othman E. Soliman, Sohier Yahia, Amany Shouma, Hala K. Shafiek, Ashraf E. Fouda, Hanan Azzam, Nashwa K. Abousamra, Rabab Mahfouz, Enas F. Goda & Solafa A. El-Sharawy. (2010) Reverse hybridization StripAssay detection of β-thalassemia mutations in northeast Egypt. Hematology 15:3, pages 182-186.
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Roshan Colah, Ajit Gorakshakar & Anita Nadkarni. (2010) Global burden, distribution and prevention of β-thalassemias and hemoglobin E disorders. Expert Review of Hematology 3:1, pages 103-117.
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Ali Asghar Kiani, Yousef Mortazavi, Sirous Zeinali & Yaghob Shirkhani. (2007) The Molecular Analysis of β-Thalassemia Mutations in Lorestan Province, Iran. Hemoglobin 31:3, pages 343-349.
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Imane Agouti, Catherine Badens, Ahmed Abouyoub, Mohamed Khattab, Fouad Sayah, Amina Barakat & Mohcine Bennani. (2007) Genotypic Correlation Between Six Common β-Thalassemia Mutations and the XmnI Polymorphism in the Moroccan Population. Hemoglobin 31:2, pages 141-149.
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Pierre A. Zalloua, Elie Aoun, Suzanne Koussa, Wissam S.Z. Asfahani & Ali Taher. (2003) The Codons 8/9 (+G) Mutation Found for the First Time in the Lebanese Population. Hemoglobin 27:1, pages 1-5.
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Mahmoud Abd El-Latif, Dvora Filon, Deborah Rund, Ariella Oppenheim & Moien Kanaan. (2002) THE β+-IVS-I-6 (T → C) MUTATION ACCOUNTS FOR HALF OF THE THALASSEMIA CHROMOSOMES IN THE PALESTINIAN POPULATIONS OF THE MOUNTAIN REGIONS. Hemoglobin 26:1, pages 33-40.
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John M. Old, Shaheen N. Khan, Ishwar Verma, Suthat Fucharoen, Marina Kleanthous, Panos Ioannou, Navaratnam Kotea, Christopher Fisher, Sheikh Riazuddin, Renu Saxena, Pranee Winichagoon, Kyriacos Kyriacou, Faizeh Al-Quobaili & Baldip Khan. (2001) A MULTI-CENTER STUDY IN ORDER TO FURTHER DEFINE THE MOLECULAR BASIS OF β-THALASSEMIA IN THAILAND, PAKISTAN, SRI LANKA, MAURITIUS, SYRIA, AND INDIA, AND TO DEVELOP A SIMPLE MOLECULAR DIAGNOSTIC STRATEGY BY AMPLIFICATION REFRACTORY MUTATION SYSTEM-POLYMERASE CHAIN REACTION. Hemoglobin 25:4, pages 397-407.
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Hossein Najmabadi, Roxana Karimi-Nejad, Solmaz Sahebjam, Farzin Pourfarzad, Shahram Teimourian, Farhad Sahebjam, Naser Amirizadeh & Mohammad H. Karimi-Nejad. (2001) THE β-THALASSEMIA MUTATION SPECTRUM IN THE IRANIAN POPULATION. Hemoglobin 25:3, pages 285-296.
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K. Kyriacou, F. Al Quobaili, E. Pavlou, G. Christopoulos, P. Ioannou & M. Kleanthous. (2000) Molecular Characterization of β-Thalassemia in Syria. Hemoglobin 24:1, pages 1-13.
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Hatice Çevirici, Can Acıpayam, Ebru Dündar Yenilmez, Fatma Burcu Belen, Esra Pekpak, Yöntem Yaman & Abdullah Tuli. (2019) Investigation of beta globin gene mutations in Syrian refugee patients with thalassemia major. Turkish Journal of Biochemistry 44:2, pages 126-129.
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Meshael M. Alswailem, Ohoud S. Alzahrani, Doha S. Alhomaidah, Rahma Alasmari, Ebtesam Qasem, Avaniyapuram Kannan Murugan, Afaf Alsagheir, Imad Brema, Bassam Ben Abbas, Mohammed Almehthel, Ali Almeqbali & Ali S. Alzahrani. (2018) Mutational analysis of rare subtypes of congenital adrenal hyperplasia in a highly inbred population. Molecular and Cellular Endocrinology 461, pages 105-111.
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Mohamad H Qari, Yasser Wali, Muneer H Albagshi, Mohammad Alshahrani, Azzah Alzahrani, Ibrahim A Alhijji, Abdulkareem Almomen, Abdullah Aljefri, Hussain H Al Saeed, Shaker Abdullah, Ahmad Al Rustumani, Khoutir Mahour & Shaker A Mousa. (2013) Regional consensus opinion for the management of Beta thalassemia major in the Arabian Gulf area. Orphanet Journal of Rare Diseases 8:1.
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Ali Reza Rezaee, Mohammad Mehdi Banoei, Elham Khalili & Massoud Houshmand. (2012) Beta-Thalassemia in Iran: New Insight into the Role of Genetic Admixture and Migration. The Scientific World Journal 2012, pages 1-7.
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Samia A. Temtamy, Mona S. Aglan & Nagwa A. Meguid. 2010. Genetic Disorders Among Arab Populations. Genetic Disorders Among Arab Populations 219 272 .
Majed Dasouki & Hatem El-Shanti. 2010. Genetic Disorders Among Arab Populations. Genetic Disorders Among Arab Populations 325 352 .
Shirley Henderson, Adele Timbs, Janice McCarthy, Alice Gallienne, Margaretha Van Mourik, Gillian Masters, Alison May, Mohamed S.M. Khalil, Anna Schuh & John Old. (2009) Incidence of haemoglobinopathies in various populations — The impact of immigration. Clinical Biochemistry 42:18, pages 1745-1756.
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Imane AgoutiCatherine BadensAhmed AbouyoubNicolas LevyMohcine Bennani. (2008) Molecular Basis of β-Thalassemia in Morocco: Possible Origins of the Molecular Heterogeneity. Genetic Testing 12:4, pages 563-568.
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Monique N. Kierlin-Duncan & Bruce A. Sullenger. (2007) Using 5′-PTMs to repair mutant β-globin transcripts. RNA 13:8, pages 1317-1327.
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N. J. Makhoul, R. S. Wells, H. Kaspar, H. Shbaklo, A. Taher, N. Chakar & P. A. Zalloua. (2005) Genetic Heterogeneity of Beta Thalassemia in Lebanon Reflects Historic and Recent Population Migration. Annals of Human Genetics 69:1, pages 55-66.
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A. S. Khalifa, Mona Salem, Eman Mounir, M. M. El-Tawil, Mohamed El-Sawy & Manal M. Abd Al-Aziz. (2004) Abnormal glucose tolerance in Egyptian beta-thalassemic patients: possible association with genotyping. Pediatric Diabetes 5:3, pages 126-132.
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M.F. Sadiq, A. Eigel & J. Horst. (2001) Spectrum of β‐thalassemia in Jordan: Identification of two novel mutations. American Journal of Hematology 68:1, pages 16-22.
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S. DAAR, H. M. HUSSEIN, T. MERGHOUB & R. KRISHNAMOORTHY. (1998) Spectrum of beta-Thalassemia Mutations in Omana. Annals of the New York Academy of Sciences 850:1 COOLEY'S ANEM, pages 404-406.
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Pascale Perrin, Rachid Bouhassa, Leı̈la Mselli, Nathalie Garguier, Victor-Marc Nigon, Chouki Bennani, Dominique Labie & Guy Trabuchet. (1998) Diversity of sequence haplotypes associated with β-thalassaemia mutations in Algeria: implications for their origin. Gene 213:1-2, pages 169-177.
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G.O. Tadmouri, Ş. Tüzmen, H. Özçelik, A. Özer, S.M. Baig, E.B. Senga & A.N. Başak. (1998) Molecular and population genetic analyses of β-Thalassemia in Turkey. American Journal of Hematology 57:3, pages 215-220.
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