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Research Article

In situ gelling formulation based on methylcellulose/pectin system for oral-sustained drug delivery to dysphagic patients

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Pages 790-797 | Received 27 Jul 2010, Accepted 14 Nov 2010, Published online: 15 Mar 2011

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Soha M. El-masry, Heba M. ElBedaiwy, Mohammad M. Abd-Alhaseeb, Mohamed S. Abdel-Maksoud & Doaa A. Habib. (2023) Green polymer altered in-situ gel oral liquid sustainable release preparation of vildagliptin suitable for dysphagic diabetic patients: assessment in-vitro & in-vivo. Pharmaceutical Development and Technology 28:7, pages 585-594.
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Yoshiaki Shirata, Asami Wakasa, Kiyoshi Miura, Hironori Nakamura, Yoshinobu Matsumoto & Tomihiro Miyada. (2017) Body heat responsive gelation of methylcellulose formulation containing betaine. Bioscience, Biotechnology, and Biochemistry 81:9, pages 1829-1836.
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Fazli Nasir, Zafar Iqbal, Amirzada Khan, Jamshaid A. Khan, Abad Khan, Fazli Khuda, Shahida Zakir, Nageen Yousaf, Ismail Khan, Yasar Shah, Muhammad Imran Khan & Naila Shahbaz. (2014) Development and evaluation of pluronic- and methylcellulose-based thermoreversible drug delivery system for insulin. Drug Development and Industrial Pharmacy 40:11, pages 1503-1508.
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Hairui Li, Yuan Yu, Sara Faraji Dana, Bo Li, Chi-Ying Lee & Lifeng Kang. (2013) Novel engineered systems for oral, mucosal and transdermal drug delivery. Journal of Drug Targeting 21:7, pages 611-629.
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Tetsuya Shimoyama, Kunihiko Itoh, Michiya Kobayashi, Shozo Miyazaki, Antony D’Emanuele & David Attwood. (2012) Oral liquid in situ gelling methylcellulose/alginate formulations for sustained drug delivery to dysphagic patients. Drug Development and Industrial Pharmacy 38:8, pages 952-960.
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Articles from other publishers (9)

Kavil Patel & Fang Liu. 2023. Pharmaceutical Formulations for Older Patients. Pharmaceutical Formulations for Older Patients 129 155 .
Pinal Chaudhari, Ranjitha Naik, Lakshmi Sruthi Mallela, Sanhita Roy, Sumit Birangal, Vivek Ghate, Sarojini Balladka Kunhanna & Shaila A Lewis. (2022) A supramolecular thermosensitive gel of ketoconazole for ocular applications: In silico, in vitro, and ex vivo studies. International Journal of Pharmaceutics 613, pages 121409.
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Lorenzo BonettiLuigi De NardoSilvia Farè. (2021) Thermo-Responsive Methylcellulose Hydrogels: From Design to Applications as Smart Biomaterials. Tissue Engineering Part B: Reviews 27:5, pages 486-513.
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Sanjana A, Mohammed Gulzar Ahmed & Jaswanth Gowda BH. (2021) Preparation and evaluation of in-situ gels containing hydrocortisone for the treatment of aphthous ulcer. Journal of Oral Biology and Craniofacial Research 11:2, pages 269-276.
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Suraj Sharma, Gunjan Sarkar, Bhupendra Srestha, Dipankar Chattopadhyay & Manas Bhowmik. (2019) In-situ fast gelling formulation for oral sustained drug delivery of paracetamol to dysphagic patients. International Journal of Biological Macromolecules 134, pages 864-868.
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K. Kanimozhi, S. Khaleel Basha & V. Sugantha Kumari. (2016) Processing and characterization of chitosan/PVA and methylcellulose porous scaffolds for tissue engineering. Materials Science and Engineering: C 61, pages 484-491.
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Irwin C. Jacobs. 2014. Pediatric Formulations. Pediatric Formulations 171 179 .
Tetsuya Shimoyama, Yuriko Miyagi, Kunihiko Itoh & Michiya Kobayashi. (2013) Effect of Storage Temperature on Gelation of Oral Methylcellulose Formulation経口メチルセルロース液剤のゲル化に及ぼす保存温度の影響. YAKUGAKU ZASSHI 133:6, pages 719-725.
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Dayang Norulfairuz Abang Zaidel & Anne S. Meyer. (2012) Biocatalytic cross-linking of pectic polysaccharides for designed food functionality: Structures, mechanisms, and reactions. Biocatalysis and Agricultural Biotechnology 1:3, pages 207-219.
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