Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 37, 2011 - Issue 9
Submit an article Journal homepage
220
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Co-administration of a nanosuspension of a poorly soluble basic compound and a solution of a proton pump inhibitor—the importance of gastrointestinal pH and solubility for the in vivo exposure

Kalle SigfridssonCorrespondence[email protected]
,
Anders LundqvistDiscovery Drug Metabolism and Pharmacokinetics & Bioanalytical Chemistry, AstraZeneca R&D Mölndal, S-431 83 Mölndal, Sweden
&
Marie StrimforsDiscovery Drug Metabolism and Pharmacokinetics & Bioanalytical Chemistry, AstraZeneca R&D Mölndal, S-431 83 Mölndal, Sweden
Pages 1036-1042 | Received 05 Jul 2010, Accepted 25 Jan 2011, Published online: 21 Mar 2011

Citations (8)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Kalle Sigfridsson & Malin Palmer. (2014) Evaluation of systemic exposure of nanoparticle suspensions subcutaneously administered to mice regarding stabilization, volume, location, concentration and size. Drug Development and Industrial Pharmacy 40:10, pages 1318-1324.
Read now
Kalle Sigfridsson, Anders Lundqvist & Marie Strimfors. (2014) Subcutaneous administration of nano- and microsuspensions of poorly soluble compounds to rats. Drug Development and Industrial Pharmacy 40:4, pages 511-518.
Read now
Kalle Sigfridsson, Anders Lundqvist & Marie Strimfors. (2013) Evaluation of exposure properties after injection of nanosuspensions and microsuspenions into the intraperitoneal space in rats. Drug Development and Industrial Pharmacy 39:11, pages 1832-1839.
Read now
Ajazuddin, Amit Alexander, Basant Amarji & Parijat Kanaujia. (2013) Synthesis, characterization and in vitro studies of pegylated melphalan conjugates. Drug Development and Industrial Pharmacy 39:7, pages 1053-1062.
Read now
Kwan Hyung Cho & Han-Gon Choi. (2013) Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs. Drug Development and Industrial Pharmacy 39:6, pages 901-908.
Read now
Lan Wang, Yanli Hao, Nan Liu, Mingshu Ma, Zhe Yin & Xiaoning Zhang. (2012) Enhance the dissolution rate and oral bioavailability of pranlukast by preparing nanosuspensions with high-pressure homogenizing method. Drug Development and Industrial Pharmacy 38:11, pages 1381-1389.
Read now

Articles from other publishers (2)

Jaydeep Patel, Anjali Dhingani, Kevin Garala, Mihir Raval & Navin Sheth. (2014) Design and development of solid nanoparticulate dosage forms of telmisartan for bioavailability enhancement by integration of experimental design and principal component analysis. Powder Technology 258, pages 331-343.
Crossref
Jan P. Möschwitzer. (2013) Drug nanocrystals in the commercial pharmaceutical development process. International Journal of Pharmaceutics 453:1, pages 142-156.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.