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Research Articles

Formulation, characterization and in vitro–in vivo evaluation of flurbiprofen-loaded nanostructured lipid carriers for transdermal delivery

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Pages 569-578 | Received 29 Feb 2012, Accepted 16 Apr 2012, Published online: 29 May 2012

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Yingjie Zhai, Lili Zhao, Zimin Wang & Guangxi Zhai. (2016) RETRACTED ARTICLE: Preparation and characterization of novel lipid nanocapsules of ropivacaine for transdermal delivery. Drug Delivery 23:2, pages (619)-(628).
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M. Sala, R. Diab, A. Elaissari & H. Fessi. (2018) Lipid nanocarriers as skin drug delivery systems: Properties, mechanisms of skin interactions and medical applications. International Journal of Pharmaceutics 535:1-2, pages 1-17.
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Shashank Jain, Niketkumar Patel, Mansi K. Shah, Pinak Khatri & Namrata Vora. (2017) Recent Advances in Lipid-Based Vesicles and Particulate Carriers for Topical and Transdermal Application. Journal of Pharmaceutical Sciences 106:2, pages 423-445.
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H.A.E. Benson, Y. Mohammed, J.E. Grice & M.S. Roberts. 2016. Nanoscience in Dermatology. Nanoscience in Dermatology 115 126 .
Andreas Lauterbach & Christel C. Müller-Goymann. (2015) Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route. European Journal of Pharmaceutics and Biopharmaceutics 97, pages 152-163.
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Fakhar ud Din, Omer Mustapha, Dong Wuk Kim, Rehmana Rashid, Jong Hyuck Park, Ju Yeon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim & Han-Gon Choi. (2015) Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect. European Journal of Pharmaceutics and Biopharmaceutics 94, pages 64-72.
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Hao Chen, Yi Wang, Yingjie Zhai, Guangxi Zhai, Zimin Wang & Jiyong Liu. (2015) Development of a ropivacaine-loaded nanostructured lipid carrier formulation for transdermal delivery. Colloids and Surfaces A: Physicochemical and Engineering Aspects 465, pages 130-136.
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Yingjie Zhai & Guangxi Zhai. (2014) Advances in lipid-based colloid systems as drug carrier for topic delivery. Journal of Controlled Release 193, pages 90-99.
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Yingjie Zhai, Xiaoye Yang, Lili Zhao, Zimin Wang & Guangxi Zhai. (2014) Lipid nanocapsules for transdermal delivery of ropivacaine: in vitro and in vivo evaluation. International Journal of Pharmaceutics 471:1-2, pages 103-111.
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