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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 1
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Research Article

Pharmacokinetic variations of tetramethylpyrazine phosphate after oral administration in hepatic precancerous mice and its hepatoprotective effects

Lili FengSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Wenchao MaoSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Jian ZhangSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Xiaoting LiuSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Yibo JiaoSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Xin ZhaoInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences Beijing 100093P. R. China
,
Xiuping WangSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Dongxing ZhangSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. China
,
Dayong CaiInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences Beijing 100093P. R. China
&
Yueqi WangSchool of Pre-clinical Medicine, Beijing University of Chinese Medicine Beijing 100029P. R. ChinaCorrespondence[email protected]
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Pages 1-8 | Received 26 Sep 2012, Accepted 04 Dec 2012, Published online: 26 Jun 2013

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Ali Nouri, Esfandiar Heidarian & Morteza Nikoukar. (2017) Effects of N-acetyl cysteine on oxidative stress and TNF-α gene expression in diclofenac-induced hepatotoxicity in rats. Toxicology Mechanisms and Methods 27:8, pages 561-567.
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Hanyi Shi, Yiran Luo, Yufa Li, Feike Zhang & Ning Liu. (2021) Tetramethylpyrazine supplementation improves performance, digestion, blood and immune state of broilers exposure to oxidative stress. Journal of Animal Physiology and Animal Nutrition 106:1, pages 132-138.
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Xin Feng, Anh Vo, Hemlata Patil, Roshan V Tiwari, Abdullah S Alshetaili, Manjeet B Pimparade & Michael A Repka. (2016) The effects of polymer carrier, hot melt extrusion process and downstream processing parameters on the moisture sorption properties of amorphous solid dispersions. Journal of Pharmacy and Pharmacology 68:5, pages 692-704.
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Jiao Cao, Qing Miao, Shan Miao, Linlin Bi, Song Zhang, Qian Yang, Xuanxuan Zhou, Meng Zhang, Yanhua Xie, Jin Zhang & Siwang Wang. (2015) Tetramethylpyrazine (TMP) exerts antitumor effects by inducing apoptosis and autophagy in hepatocellular carcinoma. International Immunopharmacology 26:1, pages 212-220.
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