Drug Development and Industrial Pharmacy, Volume 40, Issue 1 (2014)

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Drug Development and Industrial Pharmacy, Volume 40, Issue 1 (2014)

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Research Article

Article
Pharmacokinetic variations of tetramethylpyrazine phosphate after oral administration in hepatic precancerous mice and its hepatoprotective effects
Lili Feng, Wenchao Mao, Jian Zhang, Xiaoting Liu, Yibo Jiao, Xin Zhao, Xiuping Wang, Dongxing Zhang, Dayong Cai & Yueqi Wang
Pages: 1-8
Published online: 26 Jun 2013
AbstractforPharmacokinetic variations of tetramethylpyrazine phosphate after oral administration in hepatic precancerous mice and its hepatoprotective effects | Full Text | References | PDF (850.3 KB)
  • 200 Views
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Article
To enhance the efficiency of nefopam transdermal iontophoresis by using a novel method based on ion-exchange fiber
Che Xin, Wang Lihong, Han Fei, Wang Yan, Wang Qifang, Yang Yang, Yuan Yue & Li San-ming
Pages: 9-16
Published online: 15 Jan 2013
AbstractforTo enhance the efficiency of nefopam transdermal iontophoresis by using a novel method based on ion-exchange fiber | Full Text | References | PDF (419.1 KB)
  • 150 Views
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Article
Formulation study of a patch containing propranolol by design of experiments
Francesco Cilurzo, Paola Minghetti, Chiara G. M. Gennari, Antonella Casiraghi, Francesca Selmin & Luisa Montanari
Pages: 17-22
Published online: 10 Jan 2013
AbstractforFormulation study of a patch containing propranolol by design of experiments | Full Text | References | PDF (210.7 KB)
  • 415 Views
  • 15 CrossRef citations
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Article
Melt granulation in fluidized bed: a comparative study of spray-on versus in situ procedure
Ivana Mašić, Ilija Ilić, Rok Dreu, Svetlana Ibrić, Jelena Parojčić & Stanko Srčič
Pages: 23-32
Published online: 07 Jan 2013
AbstractforMelt granulation in fluidized bed: a comparative study of spray-on versus in situ procedure | Full Text | References | PDF (912.4 KB)
  • 221 Views
  • 7 CrossRef citations
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Article
Thermal sintering: a novel technique used in the design, optimization and biopharmaceutical evaluation of propranolol HCl gastric floating tablets
Meka Venkata Srikanth, Ambedkar Sunil Songa, Sreenivasa Rao Nali, Janaki Ram Battu & Venkata Ramana Murthy Kolapalli
Pages: 33-45
Published online: 15 Jan 2013
AbstractforThermal sintering: a novel technique used in the design, optimization and biopharmaceutical evaluation of propranolol HCl gastric floating tablets | Full Text | References | PDF (2.1 MB)
  • 145 Views
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Article
Quality risk analysis in a cGMP environment: multiple models for comprehensive failure mode identification during the computer system lifecycle
Brian Gervais & Deirdre M. D’Arcy
Pages: 46-60
Published online: 10 Dec 2012
AbstractforQuality risk analysis in a cGMP environment: multiple models for comprehensive failure mode identification during the computer system lifecycle | Full Text | References | PDF (975.8 KB)
  • 269 Views
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Article
Synthesis and in vitro release study of ibuprofen-loaded gelatin graft copolymer nanoparticles
Ahmed A. Haroun, N.R. El-Halawany, C. Loira-Pastoriza & P. Maincent
Pages: 61-65
Published online: 18 Dec 2012
AbstractforSynthesis and in vitro release study of ibuprofen-loaded gelatin graft copolymer nanoparticles | Full Text | References | PDF (520.2 KB)
  • 252 Views
  • 11 CrossRef citations
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Article
Development of meloxicam in situ implant formulation by quality by design principle
Hany M. Ibrahim, Tarek A. Ahmed, Muhammad D. Hussain, Ziyaur Rahman, Ahmed M. Samy, Ala A. Kaseem & Mohammad T. H. Nutan
Pages: 66-73
Published online: 09 Jan 2013
AbstractforDevelopment of meloxicam in situ implant formulation by quality by design principle | Full Text | References | PDF (1.1 MB)
  • 491 Views
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Article
In vivo brain microdialysis as a formulation-screening tool for a poorly soluble centrally acting drug
Murali Mohan Bommana, Bharat Kirthivasan, Abhijat Shikhar, Simerdeep Singh Gupta & Emilio Squillante
Pages: 74-79
Published online: 09 Jan 2013
AbstractforIn vivo brain microdialysis as a formulation-screening tool for a poorly soluble centrally acting drug | Full Text | References | PDF (1.3 MB)
  • 168 Views
  • 1 CrossRef citations
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Article
Nanosuspension of efavirenz for improved oral bioavailability: formulation optimization, in vitro, in situ and in vivo evaluation
Greeshma V. Patel, Vaibhav B. Patel, Abhishek Pathak & Sadhana J. Rajput
Pages: 80-91
Published online: 16 Jan 2013
AbstractforNanosuspension of efavirenz for improved oral bioavailability: formulation optimization, in vitro, in situ and in vivo evaluation | Full Text | References | PDF (1.8 MB)
  • 640 Views
  • 58 CrossRef citations
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Article
Solubility advantage from amorphous etoricoxib solid dispersions
Prateek Dani, Vibha Puri & A. K. Bansal
Pages: 92-101
Published online: 10 Jan 2013
AbstractforSolubility advantage from amorphous etoricoxib solid dispersions | Full Text | References | PDF (1.1 MB)
  • 392 Views
  • 9 CrossRef citations
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Article
Mixed lipid phase SMEDDS as an innovative approach to enhance resveratrol solubility
Katarina Bolko, Alenka Zvonar & Mirjana Gašperlin
Pages: 102-109
Published online: 10 Jan 2013
AbstractforMixed lipid phase SMEDDS as an innovative approach to enhance resveratrol solubility | Full Text | References | PDF (674 KB)
  • 563 Views
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Article
Effect of polymer, plasticizer and filler on orally disintegrating film
Kai Bin Liew, Yvonne Tze Fung Tan & Kok-Khiang Peh
Pages: 110-119
Published online: 11 Jan 2013
AbstractforEffect of polymer, plasticizer and filler on orally disintegrating film | Full Text | References | PDF (443.6 KB)
  • 1235 Views
  • 60 CrossRef citations
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Article
Optimization of a surfactant-free antioxidant formulation using response surface methodology
Isabel F. Almeida, Paulo C. Costa & M. Fernanda Bahia
Pages: 120-125
Published online: 22 Jan 2013
AbstractforOptimization of a surfactant-free antioxidant formulation using response surface methodology | Full Text | References | PDF (591.1 KB)
  • 134 Views
  • 3 CrossRef citations
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Article
Application and functional characterization of POVACOAT, a hydrophilic co-polymer poly(vinyl alcohol/acrylic acid/methyl methacrylate) as a hot-melt extrusion carrier
Ming Xu, Chungang Zhang, Yanfei Luo, Lishuang Xu, Xiaoguang Tao, Yanjiao Wang, Haibing He & Xing Tang
Pages: 126-135
Published online: 22 Jan 2013
AbstractforApplication and functional characterization of POVACOAT, a hydrophilic co-polymer poly(vinyl alcohol/acrylic acid/methyl methacrylate) as a hot-melt extrusion carrier | Full Text | References | PDF (1.2 MB)
  • 362 Views
  • 13 CrossRef citations
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Article
Solid-state stability studies of faropenem based on chromatography, spectroscopy and theoretical analysis
Judyta Cielecka-Piontek, Kornelia Lewandowska, Bolesław Barszcz & Aleksandra Czartek
Pages: 136-143
Published online: 28 Jan 2013
AbstractforSolid-state stability studies of faropenem based on chromatography, spectroscopy and theoretical analysis | Full Text | References | PDF (1.4 MB)
  • 132 Views
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