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Drug Development and Industrial Pharmacy Volume 41, 2015 - Issue 11
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Research Article

Monitoring of the manufacturing process for ambroxol hydrochloride tablet using NIR-chemometric methods: compression effect on content uniformity model and relevant process parameters testing

Hongqin YangCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and
,
Xiaoxiang LiaoChina Tobacco Yunnan Industrial Co., Ltd., Kunming, PR China
,
Feng PengCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and
,
Wan WangCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and
,
Yanxin LiuCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and
,
Jin YanCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and
&
Hui LiCollege of Chemical Engineering, Sichuan University, Chengdu, PR China and Correspondence[email protected]
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Pages 1877-1887 | Received 04 Sep 2014, Accepted 26 Jan 2015, Published online: 04 Mar 2015

Citations (8)

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Lauren Seabrooks, Nicole Canfield & Justin Pennington. (2016) Development of a directly correlated Raman and uHPLC-MS content uniformity method for dry powder inhalers through statistical design, chemometrics and mathematical modeling. Drug Development and Industrial Pharmacy 42:9, pages 1515-1523.
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Hongqin Yang, Yanxin Liu, Yanmei Huang, Bin Tang, Dan Guo & Hui Li. (2016) Determination of Ribavirin and Moisture in Pharmaceuticals by Near-Infrared Spectroscopy. Analytical Letters 49:13, pages 2077-2091.
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Maxwell Korang-Yeboah, Sohail Akhtar, Akhtar Siddiqui, Ziyaur Rahman & Mansoor A. Khan. (2016) Application of NIR chemometric methods for quantification of the crystalline fraction of warfarin sodium in drug product. Drug Development and Industrial Pharmacy 42:4, pages 584-594.
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Articles from other publishers (5)

Dijana Jelić, Snežana Papović, Milan Vraneš, Slobodan Gadžurić, Silvia Berto, Eugenio Alladio, Dragana Gajić & Bojan Janković. (2021) Thermo-Analytical and Compatibility Study with Mechanistic Explanation of Degradation Kinetics of Ambroxol Hydrochloride Tablets under Non-Isothermal Conditions. Pharmaceutics 13:11, pages 1910.
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Guolin Shi, Longfei Lin, Yuling Liu, Gongsen Chen, Yuting Luo, Yanqiu Wu & Hui Li. (2021) Pharmaceutical application of multivariate modelling techniques: a review on the manufacturing of tablets. RSC Advances 11:14, pages 8323-8345.
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Xia Zeng, Xinnuo Xiong, Hongqin Yang, Bin Tang, Qiaohong Du, Quan Hou, Zili Suo & Hui Li. (2018) Quantitative Monitoring the Anti-Solvent Crystallization and Storage Process for Nandrolone by Near-Infrared Spectroscopy. Journal of Pharmaceutical Sciences 107:7, pages 1928-1936.
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Nahla Rahoui, Bo Jiang, Nadia Taloub & Yu Dong Huang. (2017) Spatio-temporal control strategy of drug delivery systems based nano structures. Journal of Controlled Release 255, pages 176-201.
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Alina Porfire, Cristina Filip & Ioan Tomuta. (2017) High-throughput NIR-chemometric methods for chemical and pharmaceutical characterization of sustained release tablets. Journal of Pharmaceutical and Biomedical Analysis 138, pages 1-13.
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