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Review Article

Implantable Controlled Release Drug Delivery Systems: A Review

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Pages 1465-1502 | Published online: 20 Oct 2008

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Zahra Mohtashami, Zahra Esmaili, Molood Alsadat Vakilinezhad, Ehsan Seyedjafari & Hamid Akbari Javar. (2020) Pharmaceutical implants: classification, limitations and therapeutic applications. Pharmaceutical Development and Technology 25:1, pages 116-132.
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Sana Al-Jawadi, Pier Capasso & Manisha Sharma. (2018) The road to market implantable drug delivery systems: a review on US FDA’s regulatory framework and quality control requirements. Pharmaceutical Development and Technology 23:10, pages 953-963.
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Nachiappan Sukumar, T. Ramachandran, H. Kalaiarasi & S. Sengottuvelu. (2015) Characterization and in vivo evaluation of silk hydrogel with enhancement of dextrin, rhEGF, and alginate beads for diabetic Wistar Albino wounded rats. The Journal of The Textile Institute 106:2, pages 133-140.
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Eleanor M Pritchard & David L Kaplan. (2011) Silk fibroin biomaterials for controlled release drug delivery. Expert Opinion on Drug Delivery 8:6, pages 797-811.
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Sadhana Sharma, A Jasper Nijdam, Piyush M Sinha, Robbie J Walczak, Xuewu Liu, Mark M-C Cheng & Mauro Ferrari. (2006) Controlled-release microchips. Expert Opinion on Drug Delivery 3:3, pages 379-394.
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R. D'Souza, S. Mutalik & N. Udupa. (2006) In Vitro and In Vivo Preparation Evaluations of Bleomycin Implants and Microspheres Prepared with DL-Poly (Lactide-Co-Glycolide). Drug Development and Industrial Pharmacy 32:2, pages 175-184.
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İ. Yeni˙ce, S. Çaliş, B. Ati˙lla, H. S. Kaş, M. Özalp, M. Eki˙zoğlu, H. Bi˙lgi˙li˙ & A. A. Hincal. (2003) in vitro/in vivo evaluation of the efficiency of teicoplanin-loaded biodegradable microparticles formulated for implantation to infected bone defects. Journal of Microencapsulation 20:6, pages 705-717.
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Vivek R. Sinha & Lara Khosla. (1998) Bioabsorbable Polymers for Implantable Therapeutic Systems. Drug Development and Industrial Pharmacy 24:12, pages 1129-1138.
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U. V. Singh, S. Pandey, P. Umadevi & N. Udupa. (1997) Preparation, Characterization, and Antitumor Efficacy of Biodegradable Poly(lactic acid) Methotrexate Implantable Films. Drug Delivery 4:2, pages 101-106.
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L. Brannon-Peppas. (1994) Controlled release of β-estradiol from biodegradable microparticles within a silicone matrix. Journal of Biomaterials Science, Polymer Edition 5:4, pages 339-351.
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Rajlaxmi Deolekar, Vaibhavi A. Kalambe, Bilal Sufi & Vaibhav Urade. (2023) A Review on Implantable Drug Delivery System. International Journal of Advanced Research in Science, Communication and Technology, pages 149-153.
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Mahmoud Mostafa, Adel Al Fatease, Raid G. Alany & Hamdy Abdelkader. (2023) Recent Advances of Ocular Drug Delivery Systems: Prominence of Ocular Implants for Chronic Eye Diseases. Pharmaceutics 15:6, pages 1746.
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Mengna Li, Jing-Wei Xu, Jiayong Li, Wei Wang, Chenqi Luo, Haijie Han, Zhi-Kang Xu & Ke Yao. (2023) A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis. Bioactive Materials 20, pages 271-285.
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Kemal Çetin, Koray Şarkaya & Adil Denizli. 2023. Nanotechnology for Drug Delivery and Pharmaceuticals. Nanotechnology for Drug Delivery and Pharmaceuticals 259 294 .
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Hao Wang, Jiana Huang, Yang Liu, Xin Dong, Meng Wen & Jianhua Huang. (2022) Poloxamer188 composite electrospun poly L-lactic acid fibrous nonwoven: Sustained in vitro and in vivo release letrozole as a subcutaneous implant . Journal of Industrial Textiles 51:4_suppl, pages 6924S-6947S.
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Bilge Bicak, Serda Kecel‐Gunduz, Yasemin Budama‐Kilinc & Burak Ozdemir. (2022) Molecular docking studies of YKT tripeptide and drug delivery system with poly(ε‐caprolactone) nanoparticles. Archiv der Pharmazie 355:5, pages 2100437.
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Wei Li, Jie Tang, Dennis Lee, Thomas R. Tice, Steven P. Schwendeman & Mark R. Prausnitz. (2022) Clinical translation of long-acting drug delivery formulations. Nature Reviews Materials 7:5, pages 406-420.
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Katja Andrina Kravanja & Matjaž Finšgar. (2021) Analytical Techniques for the Characterization of Bioactive Coatings for Orthopaedic Implants. Biomedicines 9:12, pages 1936.
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Alexey Fayzullin, Alesia Bakulina, Karen Mikaelyan, Anatoly Shekhter & Anna Guller. (2021) Implantable Drug Delivery Systems and Foreign Body Reaction: Traversing the Current Clinical Landscape. Bioengineering 8:12, pages 205.
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Jack Bufton, Sungmin Jung, James C. Evans, Zeqing Bao, Dean Aguiar & Christine Allen. (2021) Cross-linked valerolactone copolymer implants with tailorable biodegradation, loading and in vitro release of paclitaxel. European Journal of Pharmaceutical Sciences 162, pages 105808.
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Rachana Yadwade, Saee Gharpure & Balaprasad Ankamwar. (2021) Nanotechnology in cosmetics pros and cons. Nano Express 2:2, pages 022003.
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Tiffany Obog Tang & George Philip Simon. (2020) Biodegradation of 3D‐printed polylactic acid milliprojections under physiological conditions. Journal of Applied Polymer Science 137:38, pages 49129.
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Rafael M. Sábio, Andréia B. Meneguin, Taís C. Ribeiro, Robson R. Silva & Marlus Chorilli. (2019) New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery. International Journal of Pharmaceutics 564, pages 379-409.
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Fernanda P. Pons-Faudoa, Andrea Ballerini, Jason Sakamoto & Alessandro Grattoni. (2019) Advanced implantable drug delivery technologies: transforming the clinical landscape of therapeutics for chronic diseases. Biomedical Microdevices 21:2.
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Bo Zhi Chen, Yuan Yang, Bei Bei Wang, Mohammad Ashfaq & Xin Dong Guo. (2019) Self-implanted tiny needles as alternative to traditional parenteral administrations for controlled transdermal drug delivery. International Journal of Pharmaceutics 556, pages 338-348.
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Hemlata Kaurav & Deepak N Kapoor. (2017) Implantable systems for drug delivery to the brain. Therapeutic Delivery 8:12, pages 1097-1107.
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Salha Boulila, Hassane Oudadesse, Rim Kallel, Bertrand Lefeuvre, Mostafa Mabrouk, Khansa Chaabouni, Fatma Makni-Ayedi, Tahia Boudawara, Abdelfattah Elfeki & Hafed Elfeki. (2017) In vivo study of hybrid biomaterial scaffold bioactive glass–chitosan after incorporation of Ciprofloxacin. Polymer Bulletin 74:10, pages 4153-4173.
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Aqdas Noreen, Zill-i-Huma Nazli, Javeria Akram, Ijaz Rasul, Asim Mansha, Nazia Yaqoob, Rehana Iqbal, Shazia Tabasum, Mohammad Zuber & Khalid Mahmood Zia. (2017) Pectins functionalized biomaterials; a new viable approach for biomedical applications: A review. International Journal of Biological Macromolecules 101, pages 254-272.
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Viness Pillay, Yahya E. Choonara & Lisa C. du Toit. 2016. Nano-Biomaterials For Ophthalmic Drug Delivery. Nano-Biomaterials For Ophthalmic Drug Delivery 407 460 .
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Fernanda M. Carbinatto, Ana Dóris de Castro, Raul C. Evangelista & Beatriz S.F. Cury. (2014) Insights into the swelling process and drug release mechanisms from cross-linked pectin/high amylose starch matrices. Asian Journal of Pharmaceutical Sciences 9:1, pages 27-34.
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