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Drug Development and Industrial Pharmacy Volume 21, 1995 - Issue 7
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Research Article

Experimental Design for a Granulation Process with “Priori” Criterias

D. Vojnovic Department of Pharmaceutical Sciences, University of Trieste, 34125, Trieste, Italy
,
M. Moneghini Department of Pharmaceutical Sciences, University of Trieste, 34125, Trieste, Italy
&
F. Rubessa Department of Pharmaceutical Sciences, University of Trieste, 34125, Trieste, Italy
Pages 823-831 | Published online: 20 Oct 2008

Citations (14)

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Read on this site (4)

Tusharmouli Mukherjee & Fotios M. Plakogiannis. (2012) Effects of process parameters on solid self-microemulsifying particles in a laboratory scale fluid bed. Pharmaceutical Development and Technology 17:4, pages 511-520.
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F. Zhou, C. Vervaet, D. L. Massart, B. Massart & J. P. Remon. (1998) Optimization of the Processing of Matrix Pellets Based on the Combination of Waxes and Starch Using Experimental Design. Drug Development and Industrial Pharmacy 24:4, pages 353-358.
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Dario Vojnovic & Daniela Chicco. (1997) Mixture Experimental Design Applied to Solubility Predictions. Drug Development and Industrial Pharmacy 23:7, pages 639-645.
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D. Vojnovic, M. Moneghini & D. Chicco. (1996) Nonclassical Experimental Design Applied in the Optimization of a Placebo Granulate Formulation in High-Shear Mixer. Drug Development and Industrial Pharmacy 22:9-10, pages 997-1004.
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Articles from other publishers (10)

Tero Närvänen, Osmo Antikainen & Jouko Yliruusi. (2009) Predicting Particle Size During Fluid Bed Granulation Using Process Measurement Data. AAPS PharmSciTech 10:4.
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Jay Trivedi. 2008. Water-Insoluble Drug Formulation, Second Edition. Water-Insoluble Drug Formulation, Second Edition 161 194 .
Xinhui Hu, John C. Cunningham & Denita Winstead. (2008) Study growth kinetics in fluidized bed granulation with at-line FBRM. International Journal of Pharmaceutics 347:1-2, pages 54-61.
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Jon Gabrielsson, Nils‐Olof Lindberg & Torbjörn Lundstedt. (2002) Multivariate methods in pharmaceutical applications. Journal of Chemometrics 16:3, pages 141-160.
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Dario Voinovich, Mariarosa Moneghini, Beatrice Perissutti & Erica Franceschinis. (2001) Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 305-313.
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A. Faure, P. York & R.C. Rowe. (2001) Process control and scale-up of pharmaceutical wet granulation processes: a review. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 269-277.
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B Rambali, L Baert & D.L Massart. (2001) Using experimental design to optimize the process parameters in fluidized bed granulation on a semi-full scale. International Journal of Pharmaceutics 220:1-2, pages 149-160.
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D. Voinovich, M. Moneghini, B. Perissutti, J. Filipovic-Grcic & I. Grabnar. (2000) Preparation in high-shear mixer of sustained-release pellets by melt pelletisation. International Journal of Pharmaceutics 203:1-2, pages 235-244.
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D Voinovich, B Campisi, M Moneghini, C Vincenzi & R Phan-Tan-Luu. (1999) Screening of high shear mixer melt granulation process variables using an asymmetrical factorial design. International Journal of Pharmaceutics 190:1, pages 73-81.
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B Campisi, D Vojnovic, D Chicco & R Phan-Tan-Luu. (1999) Melt granulation in a high shear mixer: optimization of mixture and process variables using a combined experimental design. Chemometrics and Intelligent Laboratory Systems 48:1, pages 59-70.
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