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Cancer Investigation Volume 30, 2012 - Issue 10
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ORIGINAL ARTICLE

Elevated Serum IL-8 Is Associated with the Presence of Hepatocellular Carcinoma and Independently Predicts Survival

Theodore H. WellingDepartments of Surgery and Medicine, Sections of Transplantation and Hepatology, University of Michigan Health System, MI, USACorrespondence[email protected]
,
Sherry FuDepartments of Surgery and Medicine, Sections of Transplantation and Hepatology, University of Michigan Health System, MI, USA
,
Shanshan WanDepartments of Surgery and Medicine, Sections of Transplantation and Hepatology, University of Michigan Health System, MI, USA
,
Weiping ZouDepartments of Surgery and Medicine, Sections of Transplantation and Hepatology, University of Michigan Health System, MI, USA
&
Jorge A. MarreroDepartments of Surgery and Medicine, Sections of Transplantation and Hepatology, University of Michigan Health System, MI, USA
Pages 689-697 | Published online: 16 Oct 2012

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Leung Li, Stephen L Chan, Frankie Mo, Edwin P Hui, Jane Koh, Allen K C Chan, Nelson L S Tang, Kit F Lee, Paul B S Lai, Simon C H Yu & Winnie Yeo. (2019) Correlations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma. Cancer Management and Research 11, pages 2719-2727.
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Lamiaa N. Hammad, Sahar M. Abdelraouf, Fetouh S. Hassanein, Walid A. Mohamed & Mona F. Schaalan. (2013) Circulating IL-6, IL-17 and vitamin D in hepatocellular carcinoma: Potential biomarkers for a more favorable prognosis?. Journal of Immunotoxicology 10:4, pages 380-386.
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Hans Dieter Nischalke, Janett Fischer, Alexandra Klüners, Madlen Matz‐Soja, Benjamin Krämer, Bettina Langhans, Felix Goeser, Michael Soyka, Felix Stickel, Ulrich Spengler, Jacob Nattermann, Christian P. Strassburg, Thomas Berg & Philipp Lutz. (2021) A genetic variant in toll‐like receptor 5 is linked to chemokine levels and hepatocellular carcinoma in steatohepatitis. Liver International 41:9, pages 2139-2148.
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Ya-Chin Hou, Chih-Jung Wang, Ying-Jui Chao, Hao-Yun Chen, Hao-Chen Wang, Hui-Ling Tung, Jung-Ting Lin & Yan-Shen Shan. (2018) Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes. Journal of Clinical Medicine 7:12, pages 502.
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Yi-Shu Chiu, Chung-Hsi Hsing, Chien-Feng Li, Chon-Yee Lee, Yu-Hsiang Hsu & Ming-Shi Chang. (2017) Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma. Scientific Reports 7:1.
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Franziska Mußbach, Hendrik Ungefroren, Bernd Günther, Kathrin Katenkamp, Petra Henklein, Martin Westermann, Utz Settmacher, Lennart Lenk, Susanne Sebens, Jörg P. Müller, Frank-Dietmar Böhmer & Roland Kaufmann. (2016) Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells – evidence for a role in hepatocellular carcinoma growth in vivo. Molecular Cancer 15:1.
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Yuhui Chen, Fei Teng, Geying Wang & Zhiyu Nie. (2016) Overexpression of CXCR7 induces angiogenic capacity of human hepatocellular carcinoma cells via the AKT signaling pathway. Oncology Reports 36:4, pages 2275-2281.
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Bo-Gen Ye, Hui-Chuan Sun, Xiao-Dong Zhu, Zong-Tao Chai, Yuan-Yuan Zhang, Jian-Yang Ao, Hao Cai, De-Ning Ma, Cheng-Hao Wang, Cheng-Dong Qin, Dong-Mei Gao & Zhao-You Tang. (2016) Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma. Oncotarget 7:20, pages 29333-29345.
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Sung Hoon Choi, Jun Yong Park, Wonseok Kang, Seung Up Kim, Do Young Kim, Sang Hoon Ahn, Simon Wonsang Ro & Kwang-Hyub Han. (2015) Knockdown of HIF-1? and IL-8 induced apoptosis of hepatocellular carcinoma triggers apoptosis of vascular endothelial cells. Apoptosis 21:1, pages 85-95.
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Wenjie Huang, Zhangqian Chen, Lin Zhang, Dean Tian, Daowen Wang, Daiming Fan, Kaichun Wu & Limin Xia. (2015) Interleukin-8 Induces Expression of FOXC1 to Promote Transactivation of CXCR1 and CCL2 in Hepatocellular Carcinoma Cell Lines and Formation of Metastases in Mice. Gastroenterology 149:4, pages 1053-1067.e14.
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Shanshan Wan, Ning Kuo, Ilona Kryczek, Weiping Zou & Theodore H. Welling. (2015) Myeloid cells in hepatocellular carcinoma. Hepatology 62:4, pages 1304-1312.
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Erik Johnson, Walid Yassin & Michelle Guignet. 2014. Biomarkers of Brain Injury and Neurological Disorders. Biomarkers of Brain Injury and Neurological Disorders 304 339 .
Shilu Mathew, Ashraf Ali, Hany Abdel-Hafiz, Kaneez Fatima, Mohd Suhail, Govindaraju Archunan, Nargis Begum, Syed Jahangir, Muhammad Ilyas, Adeel G.A. Chaudhary, Mohammad Al Qahtani, Salem Mohamad Bazarah & Ishtiaq Qadri. (2014) Biomarkers for virus-induced hepatocellular carcinoma (HCC). Infection, Genetics and Evolution 26, pages 327-339.
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Liang Zeng, Xiaoyan Wang, Lixue Zhou, Chao Guo, Chunlin Cai & Jinshu Wu. (2013) Clinicopathological significance of chemotactic factor IL-8, MCP-1 and MIP-1? expressions in gallbladder carcinoma. The Chinese-German Journal of Clinical Oncology 12:10, pages 481-486.
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