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Cancer Investigation Volume 5, 1987 - Issue 6
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Original Article

Isolation and Characterization of an Undifferentiated Human Colon Carcinoma Cell Line (MIP-101)

Richard M. Niles Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Sally A. Wilhelm Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Glenn D. Steele Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Bohdana Burke Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Thomas Christensen Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Daniel Dexter Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Michael J. O'Brien Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Peter Thomas Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
&
Norman Zamcheck Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
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Pages 545-552 | Published online: 11 Jun 2009

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Richard M. Niles, Sally A. Wilhelm, Peter Thomas & Norman Zamcheck. (1988) The Effect of Sodium Butyrate and Retinoic Acid on Growth and CEA Production in a Series of Human Colorectal Tumor Cell Lines Representing Different States of Differentiation. Cancer Investigation 6:1, pages 39-45.
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René Thierbach & Pablo Steinberg. (2009) Automated soft agar assay for the high-throughput screening of anticancer compounds. Analytical Biochemistry 387:2, pages 318-320.
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Timothy M. KellyPeter ThomasAniruddha Ganguly. (2007) Experimental Immunotherapy of Colorectal Carcinoma by Monoclonal Antibody ND4. Hybridoma 26:1, pages 10-16.
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Peter C. R. Emtage, Danielle Clarke, Rosa Gonzalo-Dagonzo & Richard P. Junghans. (2003) Generating Potent Th1/Tc1 T Cell Adoptive Immunotherapy Doses Using Human IL-12: Harnessing the Immunomodulatory Potential of IL-12 Without the In Vivo-Associated Toxicity. Journal of Immunotherapy 26:2, pages 97-106.
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John D Palombo, Aniruddha Ganguly, Bruce R Bistrian & Michael P Menard. (2002) The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells. Cancer Letters 177:2, pages 163-172.
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E. Jeffrey Beecham, Qiangzhong Ma, Robin Ripley & Richard P. Junghans. (2000) Coupling CD28 Co-Stimulation to Immunoglobulin T-Cell Receptor Molecules: The Dynamics of T-Cell Proliferation and Death. Journal of Immunotherapy 23:6, pages 631-642.
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E. Jeffrey Beecham, Shiara Ortiz-Pujols & Richard P. Junghans. (2000) Dynamics of Tumor Cell Killing by Human T Lymphocytes Armed With an Anti-Carcinoembryonic Antigen Chimeric Immunoglobulin T-Cell Receptor. Journal of Immunotherapy 23:3, pages 332-343.
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J. M. Jessup, D. Brown, W. Fitzgerald, R. D. Ford, A. Nachman, T. J. Goodwin & G. Spaulding. (1997) Induction of carcinoembryonic antigen expression in a three-dimensional culture system. In Vitro Cellular & Developmental Biology - Animal 33:5, pages 352-357.
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Peter Thomas, Aniruddha Gangopadhyay, Glenn SteeleJr.Jr., Charles Andrews, Hiroshi Nakazato, Shinzo Oikawa & J.Milburn Jessup. (1995) The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101. Cancer Letters 92:1, pages 59-66.
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Sarkis H. Meterissian, R.Armour Forse, Glenn D. Steele & Peter Thomas. (1995) Effect of membrane free fatty acid alterations on the adhesion of human colorectal carcinoma cells to liver macrophages and extracellular matrix proteins. Cancer Letters 89:2, pages 145-152.
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J.M. Jessup, K. Brown, S. Ishii, R. Ford, T.J. Goodwin & G. Spaulding. (1994) Simulated microgravity does not alter epithelial cell adhesion to matrix and other molecules. Advances in Space Research 14:8, pages 71-76.
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Sarkis H. Meterissian, Carol A. Toth, Glenn SteeleJr.Jr. & Peter Thomas. (1994) Kupffer cell/tumor cell interactions and hepatic metastasis in colorectal cancer. Cancer Letters 81:1, pages 5-12.
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Glenn SteeleJr.Jr.. (1994) The surgical oncologist as a key translator of basic biology to patients with gastrointestinal cancer: Asking the right questions. Annals of Surgical Oncology 1:3, pages 262-269.
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Anthony T. Petrick, Sarkis Meterissian, Glenn SteeleJrJr & Peter Thomas. (1994) Desialylation of metastatic human colorectal carcinoma cells facilitates binding to Kupffer cells. Clinical & Experimental Metastasis 12:2, pages 108-116.
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S. Ishii, R. Ford, P. Thomas, A. Nachman, G. SteeleJrJr & J.M. Jessup. (1993) CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen. Surgical Oncology 2:4, pages 255-264.
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Sarkis Meterissian, Glenn D. SteeleJrJr & Peter Thomas. (1993) Human and murine Kupffer cell function may be altered by both intrahepatic and intrasplenic tumor deposits. Clinical & Experimental Metastasis 11:2, pages 175-182.
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J. M. Jessup, T. J. Goodwin & G. Spaulding. (2004) Prospects for use of microgravity‐based bioreactors to study three‐dimensional host—tumor interactions in human neoplasia. Journal of Cellular Biochemistry 51:3, pages 290-300.
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P. Ferroni, A. Pavan, E. Martinico, M.R. Torrisi, P.P. Gazzaniga & F. Guadagni. (1993) Platelet proaggregating activity of human colorectal tumour cell lines does not correlate with the degree of differentiation. European Journal of Cancer 29:7, pages 1028-1033.
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Hans E. Wagner, Carol Ann Toth, Glenn D. SteeleJrJr & Peter Thomas. (1992) Metastatic potential of human colon cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production. Clinical & Experimental Metastasis 10:1, pages 25-31.
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Peter Thomas, Carol Ann Toth, Kulvinder S. Saini, J. Milburn Jessup & Glenn SteeleJr.Jr.. (1990) The structure, metabolism and function of the carcinoembryonic antigen gene family. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1032:2-3, pages 177-189.
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CAROL ANN TOTH & PETER THOMAS. (1990) The Effect of Interferon Treatment on 14 Human Colorectal Cancer Cell Lines: Growth and Carcinoembryonic Antigen Secretion In Vitro . Journal of Interferon Research 10:6, pages 579-588.
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Milburn Jessup & Peter Thomas. (1989) Carcinoembryonic antigen: Function in metastasis by human colorectal carcinoma. CANCER AND METASTASIS REVIEW 8:3, pages 263-280.
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John H. Stoodart, Mary Ann Lane & Richard M. Niles. (1989) Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells. Experimental Cell Research 184:1, pages 16-27.
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R. Muraro, M. Nuti, P. G. Natali, A. Bigotti, J. F. Simpson, F. J. Primus, D. Colcher, J. W. Greiner & J. Schlom. (1989) A monoclonal antibody (D612) with selective reactivity for malignant and normal gastro-intestinal epithelium. International Journal of Cancer 43:4, pages 598-607.
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Robert A. KramerJehane ZakherGeorge Kim. (1988) Role of the Glutathione Redox Cycle in Acquired and de Novo Multidrug Resistance. Science 241:4866, pages 694-697.
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