Advanced search
Publication Cover
Cancer Investigation Volume 5, 1987 - Issue 6
Submit an article Journal homepage
72
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Isolation and Characterization of an Undifferentiated Human Colon Carcinoma Cell Line (MIP-101)

Richard M. Niles Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Sally A. Wilhelm Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Glenn D. Steele Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Bohdana Burke Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Thomas Christensen Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Daniel Dexter Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Michael J. O'Brien Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
,
Peter Thomas Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
&
Norman Zamcheck Mallory Gastrointestine Research Laboratory Boston City Hospital; Department of Biochemistry and Pathology, Boston University School of Medicine; Department of Surgery, New England Deaconess Hospital; Department of Medicine and Surgery, Harvard Medical School, Boston, Massachusetts; Department of Medicine, Brown University Providence, Rhode Island, ravi
 show all
Pages 545-552 | Published online: 11 Jun 2009

References

  • Markert CL. Neoplasia: A disease of differentiation. Cancer Res 1968; 28: 1908–1914
  • Todd CW, Shively JE. Carcinoembryonic antigen—a marker of human colonic cancer. ASC Symp Ser 1978; 80: 342–356
  • Denk H, Tappeiner G, Eckerstorfer R, et al. Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal tumors and its relationship to tumor-cell differentiation. Int J Cancer 1972; 10: 262–272
  • Drewinko B, Romsdahl MD, Yang LY, et al. Establishment of a human carcinoembryonic antigen-producing cell line. Cancer Res 1976; 36: 467–475
  • Leibovitz A, Stenson JC, McCombs WB, et al. Classification of human colorectal adenocarcioma cell lines. Cancer Res 1976; 36: 4562–4569
  • Noguchi P, Wallace R, Johnson J, et al. Chamcterization of WiDr: A human colon carcinoma cell line. In Vitro 1978; 15: 40–408
  • Dexter DL, Barbosa JS, Calabresi P. N, N-Dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcioma cells. Cancer Res 1979; 39: 1020–1025
  • Rutzky LP, Kaye CI, Siciliano MJ, et al. Longitudinal karyotype and genetic signature analysis of cultured human adenocarcinoma cell lines LS180 and LS174T. Cancer Res 1980; 40: 143–1448
  • Niles RM, Wilbelm SA, Thomas P, et al. The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. Cancer Invest, In press
  • Standardization in human cytogenetics. Birth Defects original article series, D. Bergsma. National Foundation—March of Dimes, White Plains, NY 1972; Vol. 8, NO. 7
  • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains Exp Cell Res. 1961; 25: 585–621
  • Tompkins WA, Watrach AM, Schmale JD, et al. Cultural and antigenic properties of newly established cell strains derived from adenocarcinomas of the human colon and rectum. J Natl Cancer Inst 1974; 52: 1101–1110
  • Freedman VH, Shin SL. Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium. Cell 1974; 3: 355–360

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.