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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 33, 2016 - Issue 5
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Short Communication

The chondrocyte-intrinsic circadian clock is disrupted in human osteoarthritis

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Read on this site (3)

James I. Hearn, Mariam Alhilali, Minah Kim, Maggie L. Kalev-Zylinska & Raewyn C. Poulsen. (2023) N-methyl-D-aspartate receptor regulates the circadian clock in megakaryocytic cells and impacts cell proliferation through BMAL1. Platelets 34:1.
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Zhengmin Ma, Xinxin Jin, Zhuang Qian, Fang Li, Mao Xu, Ying Zhang, Xiaomin Kang, Huixia Li, Xin Gao, Liting Zhao, Zhuanmin Zhang, Yan Zhang, Shufang Wu & Hongzhi Sun. (2019) Deletion of clock gene Bmal1 impaired the chondrocyte function due to disruption of the HIF1α-VEGF signaling pathway. Cell Cycle 18:13, pages 1473-1489.
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Jing Rong, Mark Zhu, Jacob Munro, Jillian Cornish, Geraldine M McCarthy, Nicola Dalbeth & Raewyn C Poulsen. (2019) Altered expression of the core circadian clock component PERIOD2 contributes to osteoarthritis-like changes in chondrocyte activity. Chronobiology International 36:3, pages 319-331.
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Articles from other publishers (18)

Natalie Rogers & Qing-Jun Meng. (2023) Tick tock, the cartilage clock. Osteoarthritis and Cartilage 31:11, pages 1425-1436.
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Jia-ming Wei, Shao-qin Tu, Yu-xuan Wang, Sai Zhang, Yi Feng, Hong Ai & Zheng Chen. (2023) Clock gene Per1 regulates rat temporomandibular osteoarthritis through NF-κB pathway: an in vitro and in vivo study. Journal of Orthopaedic Surgery and Research 18:1.
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Lekau Dintwa, Clare E. Hughes & Emma J. Blain. (2023) Importance of mechanical cues in regulating musculoskeletal circadian clock rhythmicity: Implications for articular cartilage. Physiological Reports 11:15.
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Michal Dudek, Joe Swift & Qing-Jun Meng. (2023) The circadian clock and extracellular matrix homeostasis in aging and age-related diseases. American Journal of Physiology-Cell Physiology 325:1, pages C52-C59.
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Chenzhong Wang, Yueqi Zhang, Zhe Wang, Wei Yu, Minji Tong & Zuoqin Yan. (2022) Stabilization of hypoxia-inducible factor-1α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock. Tissue and Cell 79, pages 101942.
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M. Abdulhadi Alagha, Judit Vágó, Éva Katona, Roland Takács, Daan van der Veen, Róza Zákány & Csaba Matta. (2020) A Synchronized Circadian Clock Enhances Early Chondrogenesis. CARTILAGE 13:2_suppl, pages 53S-67S.
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Mudasir Maqbool, Ginenus Fekadu, Xinchan Jiang, Firomsa Bekele, Tadesse Tolossa, Ebisa Turi, Getahun Fetensa & Korinan Fanta. (2021) An up to date on clinical prospects and management of osteoarthritis. Annals of Medicine and Surgery 72, pages 103077.
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M. Alhilali, J.I. Hearn, J. Rong, L. Jain, S.M. Bolam, A.P. Monk, J.T. Munro, N. Dalbeth & R.C. Poulsen. (2021) IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways. Cellular Signalling 87, pages 110143.
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Kun Xiang, Zhiwei Xu, Yu-Qian Hu, Yi-Sheng He, Guo-Cui Wu, Tian-Yu Li, Xue-Rong Wang, Li-Hong Ding, Qin Zhang, Sha-Sha Tao, Dong-Qing Ye, Hai-Feng Pan & De-Guang Wang. (2021) Circadian clock genes as promising therapeutic targets for autoimmune diseases. Autoimmunity Reviews 20:8, pages 102866.
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Raewyn C Poulsen, James I Hearn & Nicola Dalbeth. (2021) The circadian clock: a central mediator of cartilage maintenance and osteoarthritis development?. Rheumatology 60:7, pages 3048-3057.
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Junlong Zhong, Bin Wang, Biao Wu, Jie Shang, Ning Jiang, Aiyong Cui, Yufeng Chen, Xianghe Xu & Huading Lu. (2021) Clock knockdown attenuated reactive oxygen species-mediated senescence of chondrocytes through restoring autophagic flux. Life Sciences 269, pages 119036.
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Francesco Dernie & Daniel Adeyoju. (2021) A matter of time: Circadian clocks in osteoarthritis and the potential of chronotherapy. Experimental Gerontology 143, pages 111163.
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Eugenie Macfarlane, Markus J. Seibel & Hong Zhou. (2020) Arthritis and the role of endogenous glucocorticoids. Bone Research 8:1.
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Guangjin Chen, Qingming Tang, Shaoling Yu, Yanling Xie, Jiwei Sun, Shue Li & Lili Chen. (2020) The biological function of BMAL1 in skeleton development and disorders. Life Sciences 253, pages 117636.
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H. Bekki, T. Duffy, N. Okubo, M. Olmer, O. Alvarez-Garcia, K. Lamia, S. Kay & M. Lotz. (2020) Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis. Osteoarthritis and Cartilage 28:7, pages 966-976.
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Farhad Md. Hossain, Yunkyung Hong, Yunho Jin, Jeonghyun Choi & Yonggeun Hong. (2019) Physiological and Pathological Role of Circadian Hormones in Osteoarthritis: Dose-Dependent or Time-Dependent?. Journal of Clinical Medicine 8:9, pages 1415.
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M.L. Kalev-Zylinska, J.I. Hearn, J. Rong, M. Zhu, J. Munro, J. Cornish, N. Dalbeth & R.C. Poulsen. (2018) Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes. Osteoarthritis and Cartilage 26:11, pages 1518-1530.
Crossref
Claire Vinatier, Eduardo Domínguez, Jerome Guicheux & Beatriz Caramés. (2018) Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis. Frontiers in Physiology 9.
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