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International Reviews of Immunology Volume 13, 1995 - Issue 1
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Original Article

Cell-mediated Cytotoxicity in Perforin-less Mice

William R. Clark Department of Biology, UCLA, Los Angeles, CA, 90024, USA; Molecular Biology Institute, UCLA, Los Angeles, CA, 90024, USA
,
Craig M. Walsh Department of Biology, UCLA, Los Angeles, CA, 90024, USA
,
Alison A. Glass Department of Biology, UCLA, Los Angeles, CA, 90024, USA
,
Manley T. F. Huang GenPharm Int'1, 297 N. Bernardo Ave., Mountain View, CA, 94043, USA
,
Rafi Ahmed Department of Microbiology & Immunology, UCLA, Los Angeles, CA, 90024, USA
&
Mehrdad Matloubian Department of Microbiology & Immunology, UCLA, Los Angeles, CA, 90024, USA
Pages 1-14 | Received 16 Sep 1994, Accepted 10 Oct 1994, Published online: 10 Jul 2009

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Ayman Oweida, Shelby Lennon, Dylan Calame, Sean Korpela, Shilpa Bhatia, Jaspreet Sharma, Caleb Graham, David Binder, Natalie Serkova, David Raben, Lynn Heasley, Eric Clambey, Raphael Nemenoff & Sana D. Karam. (2017) Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma. OncoImmunology 6:10.
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Fang Zhou. (2010) Perforin: More than Just a Pore-Forming Protein. International Reviews of Immunology 29:1, pages 56-76.
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Articles from other publishers (16)

Valerie P. Zediak, Jonathan B. Johnnidis, E. John Wherry & Shelley L. Berger. (2011) Cutting Edge: Persistently Open Chromatin at Effector Gene Loci in Resting Memory CD8+ T Cells Independent of Transcriptional Status. The Journal of Immunology 186:5, pages 2705-2709.
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SM Mansour Haeryfar, David M Conrad, Bruce L Musgrave & David W Hoskin. (2005) Antibody blockade of Thy‐1 (CD90) impairs mouse cytotoxic T lymphocyte induction by anti‐CD3 monoclonal antibody. Immunology & Cell Biology 83:4, pages 352-363.
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William J. Grossman, James W. Verbsky, Winfried Barchet, Marco Colonna, John P. Atkinson & Timothy J. Ley. (2004) Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death. Immunity 21:4, pages 589-601.
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Mark T. Esser, Rocio D. Marchese, Lisa S. Kierstead, Lynda G. Tussey, Fubao Wang, Narendra Chirmule & Michael W. Washabaugh. (2003) Memory T cells and vaccines. Vaccine 21:5-6, pages 419-430.
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Jie Zhang, Nicole Silvestri, J. Lindsay Whitton & Daniel E. Hassett. (2002) Neonates Mount Robust and Protective Adult-Like CD8 + -T-Cell Responses to DNA Vaccines . Journal of Virology 76:23, pages 11911-11919.
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M. P. MILES, L. T. MACKINNON, D. S. GROVE, N. I. WILLIAMS, J. A. BUSH, J. O. MARX, W. J. KRAEMER & A. M. MASTRO. (2002) The relationship of natural killer cell counts, perforin mRNA and CD2 expression to post‐exercise natural killer cell activity in humans. Acta Physiologica Scandinavica 174:4, pages 317-325.
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Ye Zheng, Fateh Ouaaz, Peter Bruzzo, Veena Singh, Steve Gerondakis & Amer A. Beg. (2001) NF-κB RelA (p65) Is Essential for TNF-α-Induced Fas Expression but Dispensable for Both TCR-Induced Expression and Activation-Induced Cell Death. The Journal of Immunology 166:8, pages 4949-4957.
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Denise L. Doolan & Stephen L. Hoffman. (2000) The Complexity of Protective Immunity Against Liver-Stage Malaria . The Journal of Immunology 165:3, pages 1453-1462.
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Dominik Wodarz & David C. Krakauer. (2000) Defining CTL-Induced Pathology: Implications for HIV. Virology 274:1, pages 94-104.
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Sandra Aung & Barney S. Graham. (2000) IL-4 Diminishes Perforin-Mediated and Increases Fas Ligand-Mediated Cytotoxicity In Vivo. The Journal of Immunology 164:7, pages 3487-3493.
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Charles A. Gullo, Mark T. Esser, Claudette L. Fuller & Vivian Lam Braciale. (1999) Generation of IL-2-Dependent Cytolytic T Lymphocytes (CTLs) with Altered TCR Responses Derived from Antigen-Dependent CTL Clones. The Journal of Immunology 162:11, pages 6466-6472.
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Jessica H. Spitzer & Gary G. Meadows. (1999) Modulation of Perforin, Granzyme A, and Granzyme B in Murine Natural Killer (NK), IL2 Stimulated NK, and Lymphokine-Activated Killer Cells by Alcohol Consumption. Cellular Immunology 194:2, pages 205-212.
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Imtiaz A. Khan, Tadashi Matsuura & Lloyd H. Kasper. (1998) Inducible Nitric Oxide Synthase Is Not Required for Long-Term Vaccine-Based Immunity Against Toxoplasma gondii . The Journal of Immunology 161:6, pages 2994-3000.
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SUDESH KUMAR & RICK L TARLETON. (2009) The relative contribution of antibody production and CD8 + T cell function to immune control of Trypanosoma cruzi . Parasite Immunology 20:5, pages 207-216.
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Mark T. Esser, Doris M. Haverstick, Claudette L. Fuller, Charles A. Gullo & Vivian Lam Braciale. (1998) Ca2+ Signaling Modulates Cytolytic T Lymphocyte Effector Functions. The Journal of Experimental Medicine 187:7, pages 1057-1067.
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Michael B. A. Oldstone. (1996) Virus-lymphoid cell interactions. Proceedings of the National Academy of Sciences 93:23, pages 12756-12758.
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