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Laboratory Studies

Protective Effect of Docosahexaenoic Acid Against Cyclosporine A-Induced Nephrotoxicity in Rats: A Possible Mechanism of Action

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Pages 66-71 | Received 02 Jul 2010, Accepted 28 Oct 2010, Published online: 10 Jan 2011

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Qiao Lai, Jiabao Wei, Mohammed Mahmoodurrahman, Chenxue Zhang, Shijian Quan, Tongming Li & Yang Yu. (2015) Pharmacokinetic and nephroprotective benefits of using Schisandra chinensis extracts in a cyclosporine A-based immune-suppressive regime. Drug Design, Development and Therapy 9, pages 4997-5018.
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Suat Kamisli, Osman Ciftci, Asli Cetin, Kursat Kaya, Ozden Kamisli & Hamit Celik. (2014) Fish oil protects the peripheral and central nervous systems against cisplatin-induced neurotoxicity. Nutritional Neuroscience 17:3, pages 116-126.
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Azize Yasemin Goksu Erol, Gulcan Avcı, Alper Sevimli, Elmas Ulutas & Mehmet Ozdemir. (2013) The protective effects of omega 3 fatty acids and sesame oil against cyclosporine A-induced nephrotoxicity. Drug and Chemical Toxicology 36:2, pages 241-248.
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Articles from other publishers (9)

Basma Marghani, Mohamed El-Adl, Ahmed Ateya, Basma Othman, Heba Ghamry, Mustafa Shukry, Mohamed Soliman & Mohamed Rizk. (2022) The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease. Metabolites 12:10, pages 999.
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Hiroki Muramatsu, Naoe Akimoto, Michio Hashimoto, Kenji Sugibayashi & Masanori Katakura. (2021) Influence of Polyunsaturated Fatty Acid Intake on Kidney Functions of Rats with Chronic Renal Failure. Marine Drugs 19:12, pages 692.
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Stefano Turolo, Alberto Edefonti, Alessandra Mazzocchi, Marie Louise Syren, William Morello, Carlo Agostoni & Giovanni Montini. (2021) Role of Arachidonic Acid and Its Metabolites in the Biological and Clinical Manifestations of Idiopathic Nephrotic Syndrome. International Journal of Molecular Sciences 22:11, pages 5452.
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Qinghua Wu, Xu Wang, Eugenie Nepovimova, Yun Wang, Hualin Yang & Kamil Kuca. (2018) Mechanism of cyclosporine A nephrotoxicity: Oxidative stress, autophagy, and signalings. Food and Chemical Toxicology 118, pages 889-907.
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Zhe Ma, Xuexiao Cao, Xiao Guo, Meng Wang, Xiaoliang Ren, Ranran Dong, Rui Shao & Yan Zhu. (2018) Establishment and Validation of an In Vitro Screening Method for Traditional Chinese Medicine-Induced Nephrotoxicity. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-15.
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Nahla E. El-Ashmawy, Naglaa F. Khedr, Hoda A. El-Bahrawy & Sara A. Helal. (2018) Upregulation of PPAR-γ mediates the renoprotective effect of omega-3 PUFA and ferulic acid in gentamicin-intoxicated rats. Biomedicine & Pharmacotherapy 99, pages 504-510.
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Jianjun Huang, Xuping Yao, Guobin Weng, Honggang Qi & Xiaolei Ye. (2018) Protective effect of curcumin against cyclosporine A‑induced rat nephrotoxicity. Molecular Medicine Reports.
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Masanori Katakura, Michio Hashimoto, Takayuki Inoue, Abdullah Mamun, Yoko Tanabe, Ryo Iwamoto, Makoto Arita, Satoru Tsuchikura & Osamu Shido. (2014) Omega-3 Fatty Acids Protect Renal Functions by Increasing Docosahexaenoic Acid-Derived Metabolite Levels in SHR.Cg-Leprcp/NDmcr Rats, a Metabolic Syndrome Model. Molecules 19:3, pages 3247-3263.
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Zheng Xiao, Juan Shan, Chengwen Li, Lei Luo, Jun Lu, Shengfu Li, Dan Long & Youping Li. (2013) Mechanisms of Cyclosporine-Induced Renal Cell Apoptosis: A Systematic Review. American Journal of Nephrology 37:1, pages 30-40.
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