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Research Article

Astragalosides IV inhibits high glucose-induced cell apoptosis through HGF activation in cultured human tubular epithelial cells

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Pages 400-406 | Received 11 Aug 2013, Accepted 10 Nov 2013, Published online: 07 Jan 2014

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Lin Li, Yuwei Zhang, Yudan Luo, Xianghui Meng, Guixiang Pan, Han Zhang, Yuhong Li & Boli Zhang. (2023) The Molecular Basis of the Anti-Inflammatory Property of Astragaloside IV for the Treatment of Diabetes and Its Complications. Drug Design, Development and Therapy 17, pages 771-790.
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Dong Han. (2021) Treatment with astragaloside IV reduced blood glucose, regulated blood lipids, and protected liver function in diabetic rats. Journal of International Medical Research 49:3, pages 030006051984116.
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Qingqing Chen, Yong Su, Yinghui Ju, Keke Ma, Weizu Li & Weiping Li. (2018) Astragalosides IV protected the renal tubular epithelial cells from free fatty acids-induced injury by reducing oxidative stress and apoptosis. Biomedicine & Pharmacotherapy 108, pages 679-686.
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Sha Di, Lin Han, Qing Wang, Xinkui Liu, Yingying Yang, Fan Li, Linhua Zhao & Xiaolin Tong. (2018) A Network Pharmacology Approach to Uncover the Mechanisms of Shen-Qi-Di-Huang Decoction against Diabetic Nephropathy. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-14.
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Gaofeng Song, Pengxun Han, Huili Sun, Mumin Shao, Xuewen Yu, Wenjing Wang, Dongtao Wang, Wuyong Yi, Na Ge, Shunmin Li & Tiegang Yi. (2018) Astragaloside IV ameliorates early diabetic nephropathy by inhibition of MEK1/2-ERK1/2-RSK2 signaling in streptozotocin-induced diabetic mice. Journal of International Medical Research 46:7, pages 2883-2897.
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Jun Li, Yuka Harata-Lee, Matthew D Denton, Qianjin Feng, Judith R Rathjen, Zhipeng Qu & David L Adelson. (2017) Long read reference genome-free reconstruction of a full-length transcriptome from Astragalus membranaceus reveals transcript variants involved in bioactive compound biosynthesis. Cell Discovery 3:1.
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Lei Li, Xiaojiao Hou, Rongfang Xu, Chang Liu & Menbayaer Tu. (2017) Research review on the pharmacological effects of astragaloside IV. Fundamental & Clinical Pharmacology 31:1, pages 17-36.
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Guang-dong Sun, Chao-yuan Li, Wen-peng Cui, Qiao-yan Guo, Chang-qing Dong, Hong-bin Zou, Shu-jun Liu, Wen-peng Dong & Li-ning Miao. (2016) Review of Herbal Traditional Chinese Medicine for the Treatment of Diabetic Nephropathy. Journal of Diabetes Research 2016, pages 1-18.
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Yumin Wen, Yongli Zhan, Huijie Liu, Tingting Zhao, Liping Yang, Haojun Zhang, Xi Dong & Ping Li. (2015) Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis. BMC Complementary and Alternative Medicine 15:1.
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MINGJUN LI, WENGANG WANG, LI GENG, YANRU QIN, WENJIE DONG, XUDONG ZHANG, AN QIN & MINGZHI ZHANG. (2015) Inhibition of RANKL-induced osteoclastogenesis through the suppression of the ERK signaling pathway by astragaloside IV and attenuation of titanium-particle-induced osteolysis. International Journal of Molecular Medicine 36:5, pages 1335-1344.
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Yifei Zhong, Madhav C. Menon, Yueyi Deng, Yiping Chen & John Cijiang He. (2015) Recent Advances in Traditional Chinese Medicine for Kidney Disease. American Journal of Kidney Diseases 66:3, pages 513-522.
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Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou & Zhaohui Ni. (2014) Astragaloside IV Ameliorates Renal Fibrosis via the Inhibition of Mitogen-Activated Protein Kinases and Antiapoptosis In Vivo and In Vitro. Journal of Pharmacology and Experimental Therapeutics 350:3, pages 552-562.
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