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Pediatric Hematology and Oncology Volume 32, 2015 - Issue 8
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Supportive care and acute toxicities

Serum Creatinine Versus Plasma Methotrexate Levels to Predict Toxicities in Children Receiving High-dose Methotrexate

Priya TiwariDepartment of Medical Oncology, DR. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
, MD,
M.K. ThomasDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
,
Subha PathaniaDepartment of Medical Oncology, DR. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
, MD,
Deepa DhawanDepartment of Medical Oncology, DR. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
, M.A.,
Y.K. GuptaDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
, MD,
Sreenivas VishnubhatlaDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
, PhD &
Sameer BakhshiDepartment of Medical Oncology, DR. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, IndiaCorrespondence[email protected]
, MD show all
Pages 576-584 | Received 22 Jul 2015, Accepted 24 Aug 2015, Published online: 11 Nov 2015

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Xiao Li, Zhongguo Sui, Fanbo Jing, Wen Xu, Xiangpeng Li, Qie Guo, Shuhong Sun & Xiaolin Bi. (2019) Identifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia. Cancer Management and Research 11, pages 6265-6274.
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Articles from other publishers (13)

Randal K. Buddington, Thomas Wong, Karyl K. Buddington, Torben S. Mikkelsen, Xueyuan Cao & Scott C. Howard. (2023) Early clinical indicators of acute kidney injury caused by administering high-dose methotrexate therapy to juvenile pigs. Frontiers in Nephrology 3.
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Jennifer Kendrick, Lisa Jacques, Björn Baadjes & Roxane Carr. (2022) Comparison of Sodium Bicarbonate and Lactated Ringers Hydration for High-dose Methotrexate Chemotherapy in Children. Journal of Pediatric Hematology/Oncology 44:8, pages 442-445.
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Ya-qing Shen, Zhu-jun Wang, Xiao-yan Wu, Kun Li, Zhong-jian Wang, Wen-fu Xu, Fen Zhou & Run-ming Jin. (2022) Dose-individualization Efficiently Maintains Sufficient Exposure to Methotrexate without Additional Toxicity in High-dose Methotrexate Regimens for Pediatric Acute Lymphoblastic Leukemia. Current Medical Science 42:4, pages 769-777.
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Sharada Mailankody, Venkatesan Sampath Kumar, Shah Alam Khan, Shripad D. Banavali & Jyoti Bajpai. (2021) Resource‐appropriate selection of osteosarcoma treatment protocols in low‐ and middle‐income countries. Pediatric Blood & Cancer 69:3.
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Özlem Terzi, Ali Aycicek, Ezgi Uysalol, Duygu Yildirgan, Fatma Sek & Cengiz Bayram. (2022) Utility of repeated drug level measurements after high dose methotrexate infusion for treatment planning in pediatric leukemia. Sanamed 17:3, pages 137-143.
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Himani Dhingra, Manas Kalra & Amita Mahajan. (2020) Safe administration of high‐dose methotrexate with minimal drug level monitoring: Experience from a center in north India. Pediatric Blood & Cancer 67:11.
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Manikandan Dhanushkodi. (2021) High-dose Methotrexate. Indian Journal of Medical and Paediatric Oncology 40:03, pages 424-426.
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Ryan J. Beechinor, Patrick A. Thompson, Michael F. Hwang, Ryan C. Vargo, Lisa R. Bomgaars, Jacqueline G. Gerhart, ZoAnn E. Dreyer & Daniel Gonzalez. (2019) The Population Pharmacokinetics of High-Dose Methotrexate in Infants with Acute Lymphoblastic Leukemia Highlight the Need for Bedside Individualized Dose Adjustment: A Report from the Children’s Oncology Group. Clinical Pharmacokinetics 58:7, pages 899-910.
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Hye Won Yoon, Yoon Sun Ree, Hyo Sook Song, Jae Song Kim & Eun Sun Son. (2019) Delayed Elimination After High-dose Methotrexate in Pediatric Patients with Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma. Korean Journal of Clinical Pharmacy 29:2, pages 101-108.
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Jagdish Prasad Meena, Aditya Kumar Gupta, Mansingh Parihar & Rachna Seth. (2021) Clinical profile and outcomes of Non-Hodgkin's lymphoma in children: A report from a tertiary care hospital from India. Indian Journal of Medical and Paediatric Oncology 40:01, pages 41-47.
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Alan Davidson & Scott C. Howard. (2018) Delivering modern anticancer therapies in low‐ and middle‐income settings: We can be evidence based. Pediatric Blood & Cancer 65:12.
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Kalthi Vaishnavi, Deepak Bansal, Amita Trehan, Richa Jain & Savita Verma Attri. (2018) Improving the safety of high‐dose methotrexate for children with hematologic cancers in settings without access to MTX levels using extended hydration and additional leucovorin. Pediatric Blood & Cancer 65:12.
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Prateek Tiwari, Prasanth Ganesan, Venkatraman Radhakrishnan, Rajamanickam Arivazhagan, Trivadi S. Ganesan, Manikandan Dhanushkodi, Sidharth Totadri & Tenali Gnana Sagar. (2018) Prospective evaluation of the toxicity profile, and predictors of toxicity of high dose methotrexate in patients of acute lymphoblastic leukemia/lymphoma. Pediatric Hematology Oncology Journal 3:1, pages 1-5.
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