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Pediatric Hematology and Oncology Volume 8, 1991 - Issue 4
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Original Article

Central Nervous System Disease in Childhood Acute Lymphoblastic Leukemia: Prognostic Factors and Results of Treatment

A. Kreuger Department of Pediatrics, University Hospital, S-751 85, Uppsala, Sweden
,
S. Garwicz Department of Pediatrics, University of Lund, S-221 85, Lund, Sweden
,
H. Hertz Department of Pediatrics, Rigshospitalet, DK-2100, Copenhagen, Denmark
,
C. Jonmundsson Department of Pediatrics, Landspitalinn, Reykjavik, Iceland
,
M. Latining Department of Pediatrics and Diagnostic Radiology, University of Oulu, 90220, Oulu, Finland
,
S. O. Lie Pediatric Research Institute, National Hospital of Norway, Oslo, Norway
,
P. J. Moe Department of Paediatrics, University of Trondheim, N-7000, Trondheim, Norway
,
T. T. Salmi Department of Pediatrics, ravi, Århus C, Denmark
,
H. Schröder Department of Pediatrics, ravi, SF-20520, Turku, Finland
,
M. A. Siimes Children's Hospital, University of Helsinki, Helsinki, Finland, and Children's Hospital, University of Kuopio, SF-70201, Kuopio, Finland
,
F. Wesenberg Department of Pediatrics, Haukeland University Clinic, N-5016, Bergen, Norway
,
M. Yssing Department of Pediatrics, Rigshospitalet, Copenhagen, Denmark
,
L. Åhström Department of Pediatrics, Karolinska Hospital, S-104 101, Stockholm, Sweden
&
G. Gustafsson Department of Pediatrics, Central Hospital, S-831 85, Östersund, Sweden
 show all
Pages 291-299 | Received 25 Jan 1991, Accepted 02 May 1991, Published online: 09 Jul 2009

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Fatih M. Uckun, Paul S. Gaynon, Daniel O. Stram, Martha G. Sensel, Mireille B. Sarquis & Michael Willoughby. (2001) Bone Marrow Leukemic Progenitor Cell Content in Pediatric T-Lineage Acute Lymphoblastic Leukemia Patients with an Isolated Extramedullar First Relapse. Leukemia & Lymphoma 40:3-4, pages 279-285.
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A. Kreuger. (1993) Central Nervous System Disease in Childhood All. Pediatric Hematology and Oncology 10:3, pages 297-297.
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Soeren J. Bakke, Aud Fossen, Ingebjoerg Storm-Mathiesen & Sverre O. Lie. (1993) Long-Term Cerebral Effects of CNS Chemotherapy in Children with Acute Lymphoblastic Leukemia. Pediatric Hematology and Oncology 10:3, pages 267-270.
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Giulio J. D'angio. (1993) Central Nervous System Disease in Acute Lymphoblastic Leukemia. Pediatric Hematology and Oncology 10:1, pages 109-110.
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Sverre O. Lie & Goran Gustafsson. (1992) Progress in the Treatment of Childhood Leukaemias. Annals of Medicine 24:5, pages 319-323.
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Judith M. Chessells. (1991) Central Nervous System-Directed Treatment in Acute Lymphoblastic Leukemia: Less Effective in Boys?. Pediatric Hematology and Oncology 8:4, pages v-vii.
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Articles from other publishers (14)

Shilpa Paul & Nicholas J. Short. (2022) Central Nervous System Involvement in Adults with Acute Leukemia: Diagnosis, Prevention, and Management. Current Oncology Reports 24:4, pages 427-436.
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R Parameswaran, M Yu, M-A Lyu, M Lim, M G Rosenblum, J Groffen & N Heisterkamp. (2012) Treatment of acute lymphoblastic leukemia with an rGel/BLyS fusion toxin. Leukemia 26:8, pages 1786-1796.
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Julius G. Juarez, Marilyn Thien, Aileen Dela Pena, Rana Baraz, Kenneth F. Bradstock & Linda J. Bendall. (2009) CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK. British Journal of Haematology 145:4, pages 491-499.
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T Yoshihara, A Morimoto, H Kuroda, T Imamura, H Ishida, K Tsunamoto, M Naya, S Hibi, S Todo & S Imashuku. (2005) Allogeneic stem cell transplantation in children with acute lymphoblastic leukemia after isolated central nervous system relapse: our experiences and review of the literature. Bone Marrow Transplantation 37:1, pages 25-31.
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Frank G. H. Hill, Sue Richards, Brenda Gibson, Ian Hann, John Lilleyman, Sally Kinsey, Christopher Mitchell, Christine J. Harrison & Osborn B. Eden. (2003) Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk‐stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172). British Journal of Haematology 124:1, pages 33-46.
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Oscar Ramirez, Adriana Linares, Marta Liliana Trujillo & Jorge Eduardo Caminos. (2003) WT1 mRNA in Cerebrospinal Fluid Associated With Relapse in Pediatric Lymphoblastic Leukemia. Journal of Pediatric Hematology/Oncology 25:6, pages 453-458.
Crossref
Roman Crazzolara, Alfons Kreczy, Georg Mann, Andreas Heitger, Günther Eibl, Franz-Martin Fink, Robert Möhle & Bernhard Meister. (2001) High expression of the chemokine receptor CXCR4 predicts extramedullary organ infiltration in childhood acute lymphoblastic leukaemia. British Journal of Haematology 115:3, pages 545-553.
Crossref
G Gustafsson, A Kreuger, N Clausen, S Garwicz, J Kristinsson, SO Lie, PJ Moe, M Perkkiö, M Yssing & UM Saarinen‐Pihkala. (2007) Intensified treatment of acute childhood lymphoblastic leukaemia has improved prognosis, especially in non‐high‐risk patients: the Nordic experience of 2648 patients diagnosed between 1981 and 1996. Acta Paediatrica 87:11, pages 1151-1161.
Crossref
Bjørg Klemetsdal, Trond Flægstad & Jarle Aarbakke. (2006) Is there a gender difference in red blood cell thiopurine methyltransferase activity in healthy children?. Medical and Pediatric Oncology 25:6, pages 445-449.
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H. Schroeder, S. Garwicz, J. Kristinsson, M. A. Siimes, F. Wesenberg & G. Gustafsson. (1995) Outcome after first relapse in children with acute lymphoblastic leukemia: A population-based study of 315 patients from the nordic society of pediatric hematology and oncology (NOPHO). Medical and Pediatric Oncology 25:5, pages 372-378.
Crossref
R. Aho, S. Vaittinen, K. Jahnukainen & H. Kalimo. (2008) Spread of malignant lymphoid cells into rat central nervous system with intact and disrupted blood–brain barrier. Neuropathology and Applied Neurobiology 20:6, pages 551-561.
Crossref
Judith M. Chessells. (1994) 8 Central nervous system directed therapy in acute lymphoblastic leukaemia. Baillière's Clinical Haematology 7:2, pages 349-363.
Crossref
L. Vainionpää. (1993) Clinical neurological findings of children with acute lymphoblastic leukaemia at diagnosis and during treatment. European Journal of Pediatrics 152:2, pages 115-119.
Crossref
Ian M. Hann. (2008) CNS‐DIRECTED THERAPY IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA. British Journal of Haematology 82:1, pages 2-5.
Crossref

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