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Research Article

Pure anti-dsDNA mAbs need chromatin structures to promote glomerular mesangial deposits in BALB/c mice

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Pages 179-188 | Received 19 Jun 2009, Accepted 02 Sep 2009, Published online: 19 Oct 2009

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Masumi Saito, Yumi Makino, Kumi Inoue, Yoshino Watanabe, Osamu Hoshi & Tetsuo Kubota. (2021) Anti-DNA antibodies cross-reactive with β2-glycoprotein I induce monocyte tissue factor through the TLR9 pathway. Immunological Medicine 44:2, pages 124-135.
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Marko Radic, Martin Herrmann, Johan van der Vlag & Ole Petter Rekvig. (2011) Regulatory and pathogenetic mechanisms of autoantibodies in SLE. Autoimmunity 44:5, pages 349-356.
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Tetsuo Kubota. (2023) An Emerging Role for Anti-DNA Antibodies in Systemic Lupus Erythematosus. International Journal of Molecular Sciences 24:22, pages 16499.
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Hantao Lou, Guang Sheng Ling & Xuetao Cao. (2022) Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target. Journal of Autoimmunity 132, pages 102861.
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Divya Singh, Omar Oudit, Sabastian Hajtovic, Dylan Sarbaugh, Rafatu Salis, Temitayo Adebowale, Justin James & Linda A. Spatz. (2021) Antibodies to an Epstein Barr Virus protein that cross-react with dsDNA have pathogenic potential. Molecular Immunology 132, pages 41-52.
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Anthony Chang, Marcus R. Clark & Kichul Ko. (2021) Cellular aspects of the pathogenesis of lupus nephritis. Current Opinion in Rheumatology 33:2, pages 197-204.
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Iris Jung-Won Lee & Michael P. Madaio. 2021. Lahita's Systemic Lupus Erythematosus. Lahita's Systemic Lupus Erythematosus 201 216 .
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K Inoue, M Ishizawa & T Kubota. (2020) Monoclonal anti-dsDNA antibody 2C10 escorts DNA to intracellular DNA sensors in normal mononuclear cells and stimulates secretion of multiple cytokines implicated in lupus pathogenesis. Clinical and Experimental Immunology 199:2, pages 150-162.
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Ole Petter Rekvig. (2019) The dsDNA, Anti-dsDNA Antibody, and Lupus Nephritis: What We Agree on, What Must Be Done, and What the Best Strategy Forward Could Be. Frontiers in Immunology 10.
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Young KimSeung Cheol Shim. (2018) Wolves Trapped in the NETs–The Pathogenesis of Lupus Nephritis. Journal of Rheumatic Diseases 25:2, pages 81.
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Susan Yung & Tak Mao Chan. (2017) Anti-dsDNA antibodies and resident renal cells — Their putative roles in pathogenesis of renal lesions in lupus nephritis. Clinical Immunology 185, pages 40-50.
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Ole P. Rekvig, Dhivya Thiyagarajan, Hege L. Pedersen, Kjersti D. Horvei & Natalya Seredkina. (2016) Future Perspectives on Pathogenesis of Lupus Nephritis. The American Journal of Pathology 186:11, pages 2772-2782.
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Dawn J. Caster, Liliane Hobeika, Jon B. Klein, David W. Powell & Kenneth R. McLeish. (2015) Changing the concepts of immune-mediated glomerular diseases through proteomics. PROTEOMICS - Clinical Applications 9:11-12, pages 967-971.
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Ole P. Rekvig. (2015) The anti-DNA antibody: origin and impact, dogmas and controversies. Nature Reviews Rheumatology 11:9, pages 530-540.
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Beatrice Goilav & Chaim Putterman. (2015) The Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?. Seminars in Nephrology 35:5, pages 439-443.
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Hege Lynum Pedersen, Kjersti Daae Horvei, Dhivya Thiyagarajan, Natalya Seredkina & Ole Petter Rekvig. (2015) Murine and Human Lupus Nephritis: Pathogenic Mechanisms and Theoretical Strategies for Therapy. Seminars in Nephrology 35:5, pages 427-438.
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Desmond Yap & Kar Lai. (2015) Pathogenesis of Renal Disease in Systemic Lupus Erythematosus—The Role of Autoantibodies and Lymphocytes Subset Abnormalities. International Journal of Molecular Sciences 16:12, pages 7917-7931.
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Tony N. Marion & Arnold E. Postlethwaite. (2014) Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus. Seminars in Immunopathology 36:5, pages 495-517.
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Hans-Joachim Anders & Liliana Schaefer. (2014) Beyond Tissue Injury—Damage-Associated Molecular Patterns, Toll-Like Receptors, and Inflammasomes Also Drive Regeneration and Fibrosis. Journal of the American Society of Nephrology 25:7, pages 1387-1400.
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Hans-Joachim Anders & Agnes B. Fogo. (2014) Immunopathology of lupus nephritis. Seminars in Immunopathology 36:4, pages 443-459.
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Ole Petter Rekvig & Johan Van der Vlag. (2014) The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved. Seminars in Immunopathology 36:3, pages 301-311.
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Maciej Lech & Hans-Joachim Anders. (2013) The Pathogenesis of Lupus Nephritis. Journal of the American Society of Nephrology 24:9, pages 1357-1366.
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Marko Radic & Tony N. Marion. (2013) Neutrophil extracellular chromatin traps connect innate immune response to autoimmunity. Seminars in Immunopathology 35:4, pages 465-480.
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Premasany Kanapathippillai, Annica Hedberg, Chris G. Fenton & Kristin A. Fenton. (2013) Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis. Cytokine 62:2, pages 244-252.
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A Doria & M Gatto. (2012) Nephritogenic-antinephritogenic antibody network in lupus glomerulonephritis. Lupus 21:14, pages 1492-1496.
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Yumin Xia, Rahul D. Pawar, Antonio S. Nakouzi, Leal Herlitz, Anna Broder, Kui Liu, Beatrice Goilav, Manxia Fan, Ling Wang, Quan-Zhen Li, Arturo Casadevall & Chaim Putterman. (2012) The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies. Journal of Autoimmunity 39:4, pages 398-411.
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Onkar P. Kulkarni & Hans-Joachim Anders. (2012) Lupus nephritis. How latest insights into its pathogenesis promote novel therapies. Current Opinion in Rheumatology 24:5, pages 457-465.
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Meera R. Krishnan, Congmiao Wang & Tony N. Marion. (2012) Anti-DNA autoantibodies initiate experimental lupus nephritis by binding directly to the glomerular basement membrane in mice. Kidney International 82:2, pages 184-192.
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Susan Yung & Tak Mao Chan. (2012) Autoantibodies and Resident Renal Cells in the Pathogenesis of Lupus Nephritis: Getting to Know the Unknown. Clinical and Developmental Immunology 2012, pages 1-13.
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Mariann H. Jørgensen, Ole Petter Rekvig, Rasmus S. Jacobsen, Søren Jacobsen & Kristin A. Fenton. (2011) Circulating levels of chromatin fragments are inversely correlated with anti-dsDNA antibody levels in human and murine systemic lupus erythematosus. Immunology Letters 138:2, pages 179-186.
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Johanna Atamaniuk, Yu-Yang Hsiao, Monika Mustak, Duhm Bernhard, Ludwig Erlacher, Manuela Fodinger, Beate Tiran & Karl M. Stuhlmeier. (2011) Analysing cell-free plasma DNA and SLE disease activity. European Journal of Clinical Investigation 41:6, pages 579-583.
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Tamara K Nowling & Gary S Gilkeson. (2011) Mechanisms of tissue injury in lupus nephritis. Arthritis Research & Therapy 13:6, pages 250.
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Klara Martinsson, Thomas Skogh, Seyed Ali Mousavi, Trond Berg, Jan-Ingvar Jönsson & Per Hultman. (2010) Deficiency of Activating Fcγ-Receptors Reduces Hepatic Clearance and Deposition of IC and Increases CIC Levels in Mercury-Induced Autoimmunity. PLoS ONE 5:10, pages e13413.
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