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Research Article

Effects of Ajoene on Lymphocyte and Macrophage Membrane-Dependent Functions

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Pages 15-36 | Published online: 27 Sep 2008

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Read on this site (4)

Yuki WASHIYA, Tomoaki NISHIKAWA & Tsuchiyoshi FUJINO. (2013) Enhancement of Intestinal IgA Production by Ajoene in Mice. Bioscience, Biotechnology, and Biochemistry 77:11, pages 2298-2301.
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Alireza Zamani, Mohammad Hoseinipanah, Hasan Madadi & Mehdi Arjipour. (2011) Effect of garlic consumption on the argyrophilic nucleolar organiser regions (AgNORs) in splenocytes and thymocytes of rats. Food and Agricultural Immunology 22:4, pages 345-353.
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David J. Frantz, Bronwyn G. Hughes, D. Reid Nelson, Byron K. Murray & Merrill J. Christensen. (2000) Cell Cycle Arrest and Differential Gene Expression inHT-29 Cells Exposed to an Aqueous Garlic Extract. Nutrition and Cancer 38:2, pages 255-264.
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Miodrag Čolić & Mirjana Savić. (2000) Garlic Extracts Stimulate Proliferation of Rat Lymphocytes in Vitro by Increasing IL-2 and IL-4 Production. Immunopharmacology and Immunotoxicology 22:1, pages 163-181.
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Articles from other publishers (29)

O. S. Yaremkevych & V. I. Lubenets. (2023) Тhe influence of thiosulfic acid derivatives on the morphological properties of loach embryos at the initial stages of development. Chemistry, Technology and Application of Substances 6:1, pages 99-109.
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Manjunath B. Joshi, Archana Kamath, Aswathy S. Nair, Pooja Yedehali Thimmappa, Sitaram J. Sriranjini, G.G. Gangadharan & Kapaettu Satyamoorthy. (2022) Modulation of neutrophil (dys)function by Ayurvedic herbs and its potential influence on SARS-CoV-2 infection. Journal of Ayurveda and Integrative Medicine 13:1, pages 100424.
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Mouna Moutia, Norddine Habti & Abdallah Badou. (2018) In Vitro and In Vivo Immunomodulator Activities of Allium sativum L. . Evidence-Based Complementary and Alternative Medicine 2018, pages 1-10.
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Mouna Moutia, Fouad Seghrouchni, Omar Abouelazz, Anass Elouaddari, Abdellah Al Jahid, Abdelhalim Elhou, Sellama Nadifi, Jamal Jamal Eddine, Norddine Habti & Abdallah Badou. (2016) Allium sativum L. regulates in vitro IL-17 gene expression in human peripheral blood mononuclear cells. BMC Complementary and Alternative Medicine 16:1.
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Daniel Perez-Witzke, María Auxiliadora Miranda-García, Nuris Suárez, Raquel Becerra, Kharelys Duque, Verónica Porras, Jaheli Fuenmayor & Ramon Fernando Montano. (2016) CTLA4Fc ε , a novel soluble fusion protein that binds B7 molecules and the IgE receptors, and reduces human in vitro soluble CD23 production and lymphocyte proliferation . Immunology 148:1, pages 40-55.
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Jessica Sung, Youssef Harfouche, Melissa De La Cruz, Martha P. Zamora, Yan Liu, James A. Rego & Nancy E. Buckley. (2014) Garlic ( Allium sativum ) Stimulates Lipopolysaccharide‐induced Tumor Necrosis Factor‐alpha Production from J774A.1 Murine Macrophages . Phytotherapy Research 29:2, pages 288-294.
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Miyoung Yoo, Sanghee Lee, Sunyoung Kim & Dongbin Shin. (2012) Validation of HPLC method for determination of E- and Z-Ajoene in oil-macerated garlic juice. Food Science and Biotechnology 21:1, pages 107-111.
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Hamza HANIEH, Kiyoaki NARABARA, Yuji TANAKA, Zhigang GU, Asaki ABE & Yasuhiro KONDO. (2011) Immunomodulatory effects of Allium s and Ipomoea batata extracts on lymphocytes and macrophages functions in White Leghorn chickens: In vitro study . Animal Science Journal 83:1, pages 68-76.
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Hamza HANIEH, Kiyoaki NARABARA, Mingzi PIAO, Chaogetu GERILE, Asaki ABE & Yasuhiro KONDO. (2010) Modulatory effects of two levels of dietary Alliums on immune response and certain immunological variables, following immunization, in White Leghorn chickens. Animal Science Journal 81:6, pages 673-680.
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Alireza Zamani, Aliasghar Vahidinia & Masoud Sabouri Ghannad. (2008) The effect of garlic consumption on Th1/Th2 cytokines in phytohemagglutinin (PHA) activated rat spleen lymphocytes. Phytotherapy Research 23:4, pages 579-581.
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Peter Taylor, Raquel Noriega, Carla Farah, María-Jesús Abad, Miriam Arsenak & Rafael Apitz. (2006) Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Letters 239:2, pages 298-304.
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Elena Tomás-Guillén, Anna Farriols-Danés, Carmen Cantarell-Aixendri & Juan Carlos Juárez-Giménez. (2006) Interacciones entre plantas medicinales y fármacos inmunodepresores. Medicina Clínica 127:5, pages 177-184.
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A. Dorhoi, V. Dobrean, M. Zăhan & P. Virag. (2006) Modulatory effects of several herbal extracts on avian peripheral blood cell immune responses. Phytotherapy Research 20:5, pages 352-358.
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John A Milner. (2006) Preclinical Perspectives on Garlic and Cancer. The Journal of Nutrition 136:3, pages 827S-831S.
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John A. Milner. (2006) Preclinical Perspectives on Garlic and Cancer. The Journal of Nutrition 136:3, pages 827S-831S.
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JOHN MILNER. 2006. Nutritional Oncology. Nutritional Oncology 607 614 .
Valéria Pereira Nacife, Maria de Nazaré Correia Soeiro, Rachel Novaes Gomes, Heloísa D’Avila, Hugo Caire Castro-Faria Neto & Maria de Nazareth Leal Meirelles. (2004) Morphological and Biochemical Characterization of Macrophages Activated by Carrageenan and Lipopolysaccharide In Vivo. Cell Structure and Function 29:2, pages 27-34.
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Şakir Erkoç, Sibel Sümer & Figen Erkoç. (2003) Structural and electronic properties of ajoene molecule. Journal of Molecular Structure: THEOCHEM 631:1-3, pages 271-276.
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Lorenzo Benatuil, Rafael Apitz-Castro & Egidio Romano. (2003) Ajoene inhibits the activation of human endothelial cells induced by porcine cells: implications for xenotransplantation. Xenotransplantation 10:4, pages 368-373.
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Nicola Ferri, Kohei Yokoyama, Martin Sadilek, Rodolfo Paoletti, Rafael Apitz-Castro, Michael H Gelb & Alberto Corsini. (2003) Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation. British Journal of Pharmacology 138:5, pages 811-818.
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Greg Hodge, Sandy Hodge & Ping Han. (2002) Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: Potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry 48:4, pages 209-215.
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Zhi-jun Fang, Wen-xiu Huang, Ming-hui Huang, Run-song Liang, Jing-rong Cui, Kui Wang & Meng-su Yang. (2002) Gene expression profiling of human promyelocytic leukemia HL-60 cell treated by ajoene. Chinese Journal of Cancer Research 14:1, pages 11-17.
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M. Čolić, D. Vučević, V. Kilibarda, N. Radičević & M. Savić. (2002) Modulatory effects of garlic extracts on proliferation of T-lymphocytes in vitro stimulated with concanavalin A. Phytomedicine 9:2, pages 117-124.
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Joseph R. Cronin. (2001) The Complexities of Garlic: Part 2—Research and Applications. Alternative and Complementary Therapies 7:4, pages 240-243.
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John Milner. 2000. Handbook of Nutraceuticals and Functional Foods. Handbook of Nutraceuticals and Functional Foods.
L.M. Knowles & J. A. Milner. (2000) Allyl Sulfides Modify Cell Growth. Drug Metabolism and Drug Interactions 17:1-4.
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A. Kamel & M. Saleh. 2000. Bioactive natural Products (Part D). Bioactive natural Products (Part D) 455 485 .
Hertzel Salman, Michael Bergman, Hanna Bessler, Igor Punsky & Meir Djaldetti. (1999) Effect of a garlic derivative (alliin) on peripheral blood cell immune responses. International Journal of Immunopharmacology 21:9, pages 589-597.
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JA Esté & E De Clercq. (1998) Ajoene [(e,z)-4,5,9-trithiadodeca-1, 6, 11-triene 9 oxide] does not exhibit antiviral activity at subtoxic concentrations. Biomedicine & Pharmacotherapy 52:5, pages 236-238.
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