48
Views
33
CrossRef citations to date
0
Altmetric
Research Article

Effects of Ajoene on Lymphocyte and Macrophage Membrane-Dependent Functions

, , , , , , & show all
Pages 15-36 | Published online: 27 Sep 2008

References

  • Apitz-Castro R., Cabrera S., Cruz M. R., Ledezma E., Jain M. K. Effects of garlic extract and of three pure components isolated from it in human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure. Thrombosis Res. 1983; 32: 155
  • Block E., Ahmad S., Jain M. K., Crecely R. W., Apitz-Castro R., Cruz M. R. (E, Z)-Ajoene: a potent antithrombotic agent from garlic. J. Am. Chem. Soc. 1984; 106: 8295
  • Apitz-Castro R., Jain M. K., Bartoli F., Ledezma E., Ruiz M.C., Salas R. Evidence for direct coupling of primary agonist-receptor interaction to the exposure of functional Ilb-IIIa complexes in human blood platelets. Results from studies with the antiplatelet compound ajoene. Biochem. Biophys. Acta 1094; 269: 1991
  • Tatarintsev A. V., Vrzhets P. V., Ershow D. E., Shchegolev A. A., Turgiev A. S., Karamov E. V., Kormilaeva G. V., Makarova T. V., Fedorov N. A., Varfolomer S. D. The ajoene, blockade of integrin-dependent processes in an HIV-infected cell system. VSTM-Ross Akad Med Nauk 1992; 6: 11–12
  • Urbina J. A., Marchan E., Lazardi K., Visbal G., Apitz-Castro R., Gil F., Aguirre T., Piras M. M., Piras R. Inhibition of phosphatidylcholine biosynthesis and cell proliferation in Trypanosoma cruzi by ajoene. Biochem. Pharmacol. 1993; 45: 2381
  • San-Bias G., Marino L., San-Bias F., Apitz-Castro R. Effect of ajoene, on dimorphism of Paracoccidioides brasiliensis. J. Med. Vet. Mycol. 1993; 31: 133
  • Scharfenberg K., Wagner R., Wagner K. G. The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines. Cancer lett. 1990; 53: 103
  • Sendl A., Schliack M., Loser R., Stanislaus F., Wagner H. Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic. Atherosclerosis 1992; 94: 79
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth. 1983; 65: 55
  • Hudson L., Hay F. C. Practical Immunology., Third Edition. Blackwell Scientific Publications, London 1989
  • Gebran S. J., Romano E. L., Pons H. A., Cariani L., Soyano A. N. A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene. J. Immunol. Meth. 1992; 151: 255
  • Espevik T., Nissen-Meyer J. A highly sensitive cell line: WEHI-164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Meth. 1986; 95: 99
  • Romano E., Layrisse M., Romano M., Soyano A., Layrisse Z. Electron microscopic demonstration of IgG antibodies directed to erythroblasts in Primary Acquired Pure Red Cell Aplasia. Clin. Immunopath. 1980; 17: 330
  • Gelb M. H., Jain M. K., Manel A. M., Berg O. G. Interfacial enzymology glycerolipid hydrolases. Annu. Rev. Biochem. 1995; 64: 653
  • Bott C. M., Doshi J. B., Li L. L., Mc Murtry S. A., Sanders J. L., Fox D. A. Transcriptional regulation of CD6 expression on human T-lymphocytes by phorbol ester. J. Immunol. 1994; 153: 1
  • Strahler J. R., Hailat N., Lamb B. J., Rogers K. P., Underhill J. A., Melhem R. F., Kein D. R., Zhu X., Knick R. D., Fox D. A., Hanash S. M. Activation of resting peripheral blood lymphocytes through the T-cell receptor induces rapid phosphorilation of OP 18. J. Immunol. 1992; 149: 1191
  • Kohno M., Nishizawwa N., Tsujimoto M., Nomoto H. Mitogenic signaling pathway of tumor necrosis factor involves the rapid tyrosine phosphorilation of 41.000 Mr and 43.000 Mr cytosol proteins. Biochem. J. 1990; 267: 91
  • Evans J. P.M., Mire-Sluis A. R., Hoffbrand A. V., Wickremasinghe R. G. Binding of G-CSF, GM-CSF, tumor necrosis-α and γ-interferon to cell surface receptors on human myeloid leukemia cells triggers rapid tyrosine and serine phosphorilation of a 75 kd protein. Blood. 1990; 75: 88
  • Vietor I., Schwenger P., Li W., Schlessinger J., Vilcek J. Tumor necrosis factor-induced activation and increased tyrosine phosphorilation of mitogen-activated protein (MAP) kinase in human fibroblasts. J. Biol. Chem. 1994; 268: 1993
  • Larrick J. W., Wright S. C. Cytotoxic mechanism of tumor necrosis factor-α. FASEB J. 1990; 4: 3215
  • Novogrodsky A., Vanichkin A., Patya M., Gazit A., Osherow N., Levitzki A. Prevention of lipopolysaccaride-induced lethal toxicity by tyrosine kinase inhibitors. Science. 1994; 264: 1319

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.