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Journal of Investigative Surgery Volume 26, 2013 - Issue 1
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ORIGINAL RESEARCH

Delayed Fracture Healing in Aged Senescence-Accelerated P6 Mice

Tina HistingDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,Correspondence[email protected]
,
Swantje KuntzDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
,
David StengerDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
,
Claudia ScheuerInstitute for Clinical and Experimental Surgery, University of Saarland, Homburg/Saar, Germany
,
Patric GarciaDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
,
Joerg H. HolsteinDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
,
Moritz KleinDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
,
Tim PohlemannDepartment of Trauma, Hand and Reconstructive Surgery, University of Saarland, Homburg/Saar, Germany,
&
Michael D. MengerInstitute for Clinical and Experimental Surgery, University of Saarland, Homburg/Saar, Germany
 show all
Pages 30-35 | Received 05 Feb 2012, Accepted 18 Apr 2012, Published online: 28 Dec 2012

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Xiuquan Guo, Jialiang Zhang, Xuemei Han & Ganggang Wang. (2022) LncRNA SNHG1 Delayed Fracture Healing via Modulating miR-181a-5p/PTEN Axis. Journal of Investigative Surgery 35:6, pages 1304-1312.
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T. Histing, K. Heerschop, M. Klein, C. Scheuer, D. Stenger, S.C. Herath, T. Pohlemann & M.D. Menger. (2016) Effect of Stabilization on the Healing Process of Femur Fractures in Aged Mice. Journal of Investigative Surgery 29:4, pages 202-208.
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Johannes Dominik Bastian, Mathias Bergmann, Ronald Schwyn, Marius Johann Baptist Keel & Lorin Michael Benneker. (2015) Assessment of the Breakaway Torque at the Posterior Pelvic Ring in Human Cadavers. Journal of Investigative Surgery 28:6, pages 328-333.
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Articles from other publishers (20)

Maximilian M. Menger, Ruben Manuschewski, Sabrina Ehnert, Mika F. Rollmann, Tanja C. Maisenbacher, Anne L. Tobias, Michael D. Menger, Matthias W. Laschke & Tina Histing. (2023) Radiographic, Biomechanical and Histological Characterization of Femoral Fracture Healing in Aged CD-1 Mice. Bioengineering 10:2, pages 275.
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Katrin Bundkirchen, Weikang Ye, Aleksander J. Nowak, Stefan Lienenklaus, Bastian Welke, Borna Relja & Claudia Neunaber. (2023) Fracture Healing in Elderly Mice and the Effect of an Additional Severe Blood Loss: A Radiographic and Biomechanical Murine Study. Bioengineering 10:1, pages 70.
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Dominik Saul & Sundeep Khosla. (2022) Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence. Endocrine Reviews 43:6, pages 984-1002.
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E.A. Gorter, C.R. Reinders, P. Krijnen, N.M. Appelman-Dijkstra & I.B. Schipper. (2021) The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies. Bone Reports 15, pages 101117.
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Gareth Ryan, Richard Magony, Hilary Gortler, Charles Godbout, Emil H. Schemitsch & Aaron Nauth. (2021) Systemically impaired fracture healing in small animal research: A review of fracture repair models. Journal of Orthopaedic Research 39:7, pages 1359-1367.
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Arash Khojasteh, Farshid Bastami & Marzieh Alikhasi. 2021. Integrated Procedures in Facial Cosmetic Surgery. Integrated Procedures in Facial Cosmetic Surgery 687 702 .
Robert G. Stigler, Kathrin Becker, Elvin Hasanov, Romed Hörmann, Robert Gassner & Günter Lepperdinger. (2019) Osteocyte numbers decrease only in postcranial but not in cranial bones in humans of advanced age. Annals of Anatomy - Anatomischer Anzeiger 226, pages 57-63.
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Melanie Haffner-Luntzer, Astrid Liedert & Anita Ignatius. (2016) Mechanobiology of bone remodeling and fracture healing in the aged organism. Innovative Surgical Sciences 1:2, pages 57-63.
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Emmanuel Gibon, Laura Lu & Stuart B. Goodman. (2016) Aging, inflammation, stem cells, and bone healing. Stem Cell Research & Therapy 7:1.
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Melanie Haffner-Luntzer, Julia Kemmler, Verena Heidler, Katja Prystaz, Thorsten Schinke, Michael Amling, Anna Kovtun, Anna E. Rapp, Anita Ignatius & Astrid Liedert. (2016) Inhibition of Midkine Augments Osteoporotic Fracture Healing. PLOS ONE 11:7, pages e0159278.
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T. Histing, A. Andonyan, M. Klein, C. Scheuer, D. Stenger, J.H. Holstein, N.T. Veith, T. Pohlemann & M.D. Menger. (2016) Obesity does not affect the healing of femur fractures in mice. Injury 47:7, pages 1435-1444.
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Melanie Haffner-Luntzer, Anna Kovtun, Anna E. Rapp & Anita Ignatius. (2016) Mouse Models in Bone Fracture Healing Research. Current Molecular Biology Reports 2:2, pages 101-111.
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A. Hamish Simpson & Iain R. Murray. (2016) Main differences in osteoporotic fracture models: which should I use?. Injury 47, pages S15-S20.
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Yufeng Zhang, Lu Wang, Feng Deng, Hongmei Qiu & Xiaohong Wu. (2015) Determination of a critical size calvarial defect in senile osteoporotic mice model based on in vivo micro-computed tomography and histological evaluation. Archives of Gerontology and Geriatrics 61:1, pages 44-55.
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Moritz Klein, Andrea Stieger, David Stenger, Claudia Scheuer, Jörg H. Holstein, Tim Pohlemann, Michael D. Menger & Tina Histing. (2015) Comparison of healing process in open osteotomy model and open fracture model: Delayed healing of osteotomies after intramedullary screw fixation. Journal of Orthopaedic Research 33:7, pages 971-978.
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Malte Steiner, David Volkheimer, Nicholaus Meyers, Tim Wehner, Hans-Joachim Wilke, Lutz Claes & Anita Ignatius. (2015) Comparison between Different Methods for Biomechanical Assessment of Ex Vivo Fracture Callus Stiffness in Small Animal Bone Healing Studies. PLOS ONE 10:3, pages e0119603.
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A. Hamish Simpson & Iain R. Murray. (2014) Osteoporotic Fracture Models. Current Osteoporosis Reports 13:1, pages 9-15.
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Luke A. Lopas, Nicole S. Belkin, Patricia L. Mutyaba, Chancellor F. Gray, Kurt D. Hankenson & Jaimo Ahn. (2014) Fractures in Geriatric Mice Show Decreased Callus Expansion and Bone Volume. Clinical Orthopaedics and Related Research® 472:11, pages 3523-3532.
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R. Michael Ackerson, Laura C. Shum, Andrew R. Berry, Allan L. Bucknell & Karen B. King. (2014) In Vivo Model to Measure Bone Repair Efficacy of Nanoparticle-based Drug Delivery. Orthopedics 37:8.
Crossref
Brigitte von Rechenberg. (2014) Animal models in bone repair. Drug Discovery Today: Disease Models 13, pages 23-27.
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