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Inhalation Toxicology
International Forum for Respiratory Research
Volume 3, 1991 - Issue 1
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Research Article

Effects of Phosgene Exposure on Lung Arachidonic Acid Metabolism

Michael C. Madden Center for Environmental Medicine and Lung Biology and the Department of Medicine, University of North Carolina, Chapel Hill, North Carolina
,
Mitchell Friedrnan Center for Environmental Medicine and Lung Biology and the Department of Medicine, University of North Carolina, Chapel Hill, North Carolina
,
Lynette L. Keyes NSI-Environmental Sciences, Research Triangle Park, North Carolina
,
Hillel S. Koren Cell and Molecular Biology Section and Immunotoxicology Section, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina
&
Gary R. Burleson Cell and Molecular Biology Section and Immunotoxicology Section, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina
Pages 73-90 | Published online: 27 Sep 2008

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Stephen T. Hobson, Richard A. Richieri & Missag H. Parseghian. (2021) Phosgene: toxicology, animal models, and medical countermeasures. Toxicology Mechanisms and Methods 31:4, pages 293-307.
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Dorian S. Olivera, Heidi Hoard-Fruchey & Alfred M. Sciuto. (2017) Evaluation of an in vitro screening model to assess phosgene inhalation injury. Toxicology Mechanisms and Methods 27:1, pages 45-51.
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J. Pauluhn, A. Carson, D. L. Costa, T. Gordon, U. Kodavanti, J. A. Last, M. A. Matthay, K. E. Pinkerton & A. M. Sciuto. (2007) Workshop Summary: Phosgene-Induced Pulmonary Toxicity Revisited: Appraisal of Early and Late Markers of Pulmonary Injury From Animal Models With Emphasis on Human Significance. Inhalation Toxicology 19:10, pages 789-810.
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Alfred M. Sciuto & Richard R. Stotts. (1998) Posttreatment with Eicosatetraynoic Acid Decreases Lung Edema in Guinea Pigs Exposed to Phosgene: The Role of Leukotrienes. Experimental Lung Research 24:3, pages 273-292.
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Dorien Wijte, Marcel J. Alblas, Daan Noort, Jan P. Langenberg & Herman P.M. van Helden. (2011) Toxic effects following phosgene exposure of human epithelial lung cells in vitro using a CULTEX® system. Toxicology in Vitro 25:8, pages 2080-2087.
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George M. Woodall, Jeffrey S. Gift & Gary L. Foureman. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Alfred Sciuto. 2005. Inhalation Toxicology, Second Edition. Inhalation Toxicology, Second Edition 457 483 .
Jonathan Borak & Werner F. Diller. (2001) Phosgene Exposure: Mechanisms of Injury and Treatment Strategies. Journal of Occupational and Environmental Medicine 43:2, pages 110-119.
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Gary R Burleson. (2000) Models of respiratory immunotoxicology and host resistance. Immunopharmacology 48:3, pages 315-318.
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Terry L. Noah, Anthony M. Paradiso, Michael C. Madden, Karen P. McKinnon & Robert B. Devlin. (1991) The Response of a Human Bronchial Epithelial Cell Line to Histamine: Intracellular Calcium Changes and Extracellular Release of Inflammatory Mediators. American Journal of Respiratory Cell and Molecular Biology 5:5, pages 484-492.
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