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Inhalation Toxicology
International Forum for Respiratory Research
Volume 7, 1995 - Issue 6
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Research Article

Consideration of Temporal Toxicity Challenges Current Default Assumptions

Pages 927-946 | Published online: 27 Sep 2008

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Peter M. J. Bos, Lya G. Soeteman-Hernández & Reinskje Talhout. (2021) Risk assessment of components in tobacco smoke and e-cigarette aerosols: a pragmatic choice of dose metrics. Inhalation Toxicology 33:3, pages 81-95.
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Eileen D. Kuempel, Lisa M. Sweeney, John B. Morris & Annie M. Jarabek. (2015) Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation. Journal of Occupational and Environmental Hygiene 12:sup1, pages S18-S40.
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D. Gayle DeBord, Lyle Burgoon, Stephen W. Edwards, Lynne T. Haber, M. Helen Kanitz, Eileen Kuempel, Russell S. Thomas & Berran Yucesoy. (2015) Systems Biology and Biomarkers of Early Effects for Occupational Exposure Limit Setting. Journal of Occupational and Environmental Hygiene 12:sup1, pages S41-S54.
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Annie M. Jarabek, Bahman Asgharian & Frederick J. Miller. (2005) Dosimetric Adjustments for Interspecies Extrapolation of Inhaled Poorly Soluble Particles (PSP). Inhalation Toxicology 17:7-8, pages 317-334.
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AnnieM. Jarabek. (1995) Interspecies extrapolation based on mechanistic determinants of chemical disposition. Human and Ecological Risk Assessment: An International Journal 1:5, pages 641-662.
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H. Woodward, A. Schroeder, A. de Nazelle, C.C. Pain, M.E.J. Stettler, H. ApSimon, A. Robins & P.F. Linden. (2023) Do we need high temporal resolution modelling of exposure in urban areas? A test case. Science of The Total Environment 885, pages 163711.
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Amy J. Clippinger, David Allen, Holger Behrsing, Kelly A. BéruBé, Michael B. Bolger, Warren Casey, Michael DeLorme, Marianna Gaça, Sean C. Gehen, Kyle Glover, Patrick Hayden, Paul Hinderliter, Jon A. Hotchkiss, Anita Iskandar, Brian Keyser, Karsta Luettich, Lan Ma-Hock, Anna G. Maione, Patrudu Makena, Jodie Melbourne, Lawrence Milchak, Sheung P. Ng, Alicia Paini, Kathryn Page, Grace Patlewicz, Pilar Prieto, Hans Raabe, Emily N. Reinke, Clive Roper, Jane Rose, Monita Sharma, Wayne Spoo, Peter S. Thorne, Daniel M. Wilson & Annie M. Jarabek. (2018) Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity. Toxicology in Vitro 52, pages 131-145.
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Amy J. Clippinger, David Allen, Annie M. Jarabek, Marco Corvaro, Marianna Gaça, Sean Gehen, Jon A. Hotchkiss, Grace Patlewicz, Jodie Melbourne, Paul Hinderliter, Miyoung Yoon, Dongeun Huh, Anna Lowit, Barbara Buckley, Michael Bartels, Kelly BéruBé, Daniel M. Wilson, Ian Indans & Mathieu Vinken. (2018) Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report. Toxicology in Vitro 48, pages 53-70.
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Ji Young Hong, So Yeon Yu, Gi Won Kim, Jeong Jin Ahn, Youngjoo Kim, Seri Lim, Sang Wook Son & Seung Yong Hwang. (2016) Identification of time-dependent biomarkers and effects of exposure to volatile organic compounds using high-throughput analysis. Environmental Toxicology 31:11, pages 1563-1570.
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Harvey J. ClewellIIIIII. 2010. Quantitative Modeling in Toxicology. Quantitative Modeling in Toxicology 399 428 .
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William K. Boyes, Marina V. Evans, Christopher Eklund, Paul Janssen & Jane Ellen Simmons. (2005) Duration Adjustment of Acute Exposure Guideline Level Values for Trichloroethylene Using a Physiologically-Based Pharmacokinetic Model. Risk Analysis 25:3, pages 677-686.
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Juergen Pauluhn. 2003. Encyclopedia of Agrochemicals. Encyclopedia of Agrochemicals.
P.Robinan Gentry, Tammie R. Covington, Melvin E. Andersen & Harvey J. ClewellIIIIII. (2002) Application of a Physiologically Based Pharmacokinetic Model for Isopropanol in the Derivation of a Reference Dose and Reference Concentration. Regulatory Toxicology and Pharmacology 36:1, pages 51-68.
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M.V. Evans, W.K. Boyes, J.E. Simmons, D.K. Litton & M.R. Easterling. (2002) A comparison of Haber's rule at different ages using a physiologically based pharmacokinetic (PBPK) model for chloroform in rats. Toxicology 176:1-2, pages 11-23.
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Rene B.J. Remillard & Nigel J. Bunce. (2002) Use of Haber's Rule to estimate the risk of diabetes from background exposures to dioxin-like compounds. Toxicology Letters 131:3, pages 161-166.
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Harvey J Clewell3rd3rd, Melvin E Andersen & Hugh A Barton. (2002) A consistent approach for the application of pharmacokinetic modeling in cancer and noncancer risk assessment.. Environmental Health Perspectives 110:1, pages 85-93.
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GE HatchU Kodavanti, K Crissman, R Slade & D Costa. (2016) An ‘injury-time integral’ model for extrapolating from acute to chronic effects of phosgene. Toxicology and Industrial Health 17:5-10, pages 285-293.
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William K. Boyes. 2003. Patty's Toxicology. Patty's Toxicology.
Jurgen Pauluhn & Ulrich Mohr. (2016) Review Article: Inhalation Studies in Laboratory Animals—Current Concepts and Alternatives. Toxicologic Pathology 28:5, pages 734-753.
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Frederick J Miller, Paul M Schlosser & Derek B Janszen. (2000) Haber’s rule: a special case in a family of curves relating concentration and duration of exposure to a fixed level of response for a given endpoint. Toxicology 149:1, pages 21-34.
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W K Boyes, P J Bushnell, K M Crofton, M Evans & J E Simmons. (2000) Neurotoxic and pharmacokinetic responses to trichloroethylene as a function of exposure scenario.. Environmental Health Perspectives 108:suppl 2, pages 317-322.
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D.Alan Warren, Thomas G. Reigle, Srinivasa Muralidhara & Cham E. Dallas. (1998) Schedule-Controlled Operant Behavior of Rats During 1,1,1-Trichloroethane Inhalation: Relationship to Blood and Brain Solvent Concentrations1. Neurotoxicology and Teratology 20:2, pages 143-153.
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Minge Xie & Douglas Simpson. 1998. Case Studies in Environmental Statistics. Case Studies in Environmental Statistics 121 141 .
Thomas McCurdy. (1997) Human activities that may lead to high inhaled intake doses in children aged 6–13. Environmental Toxicology and Pharmacology 4:3-4, pages 251-260.
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Matthew S. Bogdanffy & Annie M. Jarabek. (1995) Understanding mechanisms of inhaled toxicants: implications for replacing default factors with chemical-specific data. Toxicology Letters 82-83, pages 919-932.
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