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Gynecological Endocrinology Volume 30, 2014 - Issue 1
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Progesterone Antagonist

Progesterone antagonist, RU486, represses LHCGR expression and LH/hCG signaling in cultured luteinized human mural granulosa cells

Yuval YungHuman Reproduction LabCorrespondence[email protected]
,
Ettie MamanIVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Centre, Tel-Hashomer Ramat GanIsrael (affiliated to the Sackler School of MedicineTel-Aviv UniversityTel-Aviv, Israel)
,
Libby OphirHuman Reproduction Lab
,
Nirit RubinsteinHuman Reproduction Lab
,
Eran BarzilayIVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Centre, Tel-Hashomer Ramat GanIsrael (affiliated to the Sackler School of MedicineTel-Aviv UniversityTel-Aviv, Israel)
,
Gil M. YerushalmiIVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Centre, Tel-Hashomer Ramat GanIsrael (affiliated to the Sackler School of MedicineTel-Aviv UniversityTel-Aviv, Israel)
&
Ariel HourvitzIVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Centre, Tel-Hashomer Ramat GanIsrael (affiliated to the Sackler School of MedicineTel-Aviv UniversityTel-Aviv, Israel)
 show all
Pages 42-47 | Received 11 Apr 2013, Accepted 13 Sep 2013, Published online: 22 Oct 2013

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Eran Barzilay, Yuval Yung, Lev Shapira, Jigal Haas, Libby Ophir, Gil M. Yerushalmi, Ettie Maman & Ariel Hourvitz. (2014) Differential expression of poliovirus receptor, regulator of G-protein signaling 11 and erythrocyte protein band 4.1-like 3 in human granulosa cells during follicular growth and maturation. Gynecological Endocrinology 30:9, pages 660-663.
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Articles from other publishers (16)

Kira V. Derkach, Ivan A. Lebedev, Irina Yu. Morina, Andrey A. Bakhtyukov, Alena S. Pechalnova, Viktor N. Sorokoumov, Veronica S. Kuznetsova, Irina V. Romanova & Alexander O. Shpakov. (2023) Comparison of Steroidogenic and Ovulation-Inducing Effects of Orthosteric and Allosteric Agonists of Luteinizing Hormone/Chorionic Gonadotropin Receptor in Immature Female Rats. International Journal of Molecular Sciences 24:23, pages 16618.
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H Jeon, Y Choi, M Brännström, J W Akin, T E Curry & M Jo. (2023) Cortisol/glucocorticoid receptor: a critical mediator of the ovulatory process and luteinization in human periovulatory follicles. Human Reproduction 38:4, pages 671-685.
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Blanche C Ip, Elizabeth Leary, Benjamin Knorlein, David Reich, Vivian Van, Joshua Manning & Jeffrey R Morgan. (2022) 3D Microtissues Mimic the Architecture, Estradiol Synthesis, and Gap Junction Intercellular Communication of the Avascular Granulosa. Toxicological Sciences 186:1, pages 29-42.
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Camille Fraichard, Fidéline Bonnet-Serrano, Christelle Laguillier-Morizot, Marylise Hebert-Schuster, René Lai-Kuen, Jeanne Sibiude, Thierry Fournier, Marie Cohen & Jean Guibourdenche. (2021) Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine Function. International Journal of Molecular Sciences 22:2, pages 683.
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S. Divyashree, P. Janhavi, P.V. Ravindra & S.P. Muthukumar. (2019) Experimental models of polycystic ovary syndrome: An update. Life Sciences 237, pages 116911.
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Richard J. Kordus, Akhtar Hossain, Michael C. Corso, Hrishikesh Chakraborty, Gail F. Whitman-Elia & Holly A. LaVoie. (2019) Cumulus cell pappalysin-1, luteinizing hormone/choriogonadotropin receptor, amphiregulin and hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 mRNA levels associate with oocyte developmental competence and embryo outcomes. Journal of Assisted Reproduction and Genetics 36:7, pages 1457-1469.
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Scott Convissar, Nicola J. Winston, Michelle A. Fierro, Humberto Scoccia, Alberuni M. Zamah & Carlos Stocco. (2019) Sp1 regulates steroidogenic genes and LHCGR expression in primary human luteinized granulosa cells. The Journal of Steroid Biochemistry and Molecular Biology 190, pages 183-192.
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Silke M. Haen, Mari Heinonen, Johannes Kauffold, Markku Heikinheimo, Lia L. Hoving, Nicoline M. Soede & Olli A. T. Peltoniemi. (2019) GnRH‐agonist deslorelin implant alters the progesterone release pattern during early pregnancy in gilts. Reproduction in Domestic Animals 54:3, pages 464-472.
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Libby Ophir, Yuval Yung, Gil Mordechai Yerushalmi, Micha Baum, Ronit Machtinger, Ettie Maman & Ariel Hourvitz. (2019) An optimized model for hCG stimulation of human mural granulosa cell culture. Reproductive Biology 19:1, pages 67-74.
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Patrick R Hannon, Diane M Duffy, Katherine L Rosewell, Mats Brännström, James W Akin & Thomas E CurryJr.Jr.. (2018) Ovulatory Induction of SCG2 in Human, Nonhuman Primate, and Rodent Granulosa Cells Stimulates Ovarian Angiogenesis. Endocrinology 159:6, pages 2447-2458.
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Hiroshi Kishi, Yoshikazu Kitahara, Fumiharu Imai, Kohshiro Nakao & Hiroto Suwa. (2018) Expression of the gonadotropin receptors during follicular development. Reproductive Medicine and Biology 17:1, pages 11-19.
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Cécile Choux, Julie Barberet, Perrine Ginod, Jonathan Cottenet, Céline Bruno, Eric Benzénine, Paul Sagot & Patricia Fauque. (2017) Severe ovarian hyperstimulation syndrome modifies early maternal serum beta-human chorionic gonadotropin kinetics, but obstetrical and neonatal outcomes are not impacted. Fertility and Sterility 108:4, pages 650-658.e2.
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Yohan Choi, Kalin Wilson, Patrick R. Hannon, Katherine L. Rosewell, Mats Brännström, James W. Akin, Thomas E. CurryJr.Jr. & Misung Jo. (2017) Coordinated Regulation Among Progesterone, Prostaglandins, and EGF-Like Factors in Human Ovulatory Follicles. The Journal of Clinical Endocrinology & Metabolism 102:6, pages 1971-1982.
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Alexandra C. Kölbl, Amelie E. Birk, Christina Kuhn, Udo Jeschke & Ulrich Andergassen. (2016) Influence of VEGFR and LHCGR on endometrial adenocarcinoma. Oncology Letters 12:3, pages 2092-2098.
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Ya-Qin Wang, Jin Luo, Wang-Min Xu, Qin-Zhen Xie, Wen-Jie Yan, Geng-Xiang Wu & Jin Yang. (2015) Can steroidal ovarian suppression during the luteal phase after oocyte retrieval reduce the risk of severe OHSS?. Journal of Ovarian Research 8:1.
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Y. Yung, S. Aviel-Ronen, E. Maman, N. Rubinstein, C. Avivi, R. Orvieto & A. Hourvitz. (2014) Localization of luteinizing hormone receptor protein in the human ovary. Molecular Human Reproduction 20:9, pages 844-849.
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