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Research Article

Are we using excessive neuroleptics? An argument for systematic neuroleptic dose reduction in stable patients with schizophrenia with specific reference to clozapine

& , MBBS MPhil (Leeds), FRCPsych, FRANZCP, DPM
Pages 138-147 | Published online: 26 May 2010

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Gary Remington, Ofer Agid & George Foussias. (2011) Schizophrenia as a disorder of too little dopamine: implications for symptoms and treatment. Expert Review of Neurotherapeutics 11:4, pages 589-607.
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Articles from other publishers (9)

Jan P A M Bogers, George Hambarian, Maykel Michiels, Jentien Vermeulen & Lieuwe de Haan. (2020) Risk Factors for Psychotic Relapse After Dose Reduction or Discontinuation of Antipsychotics in Patients With Chronic Schizophrenia: A Systematic Review and Meta-analysis. Schizophrenia Bulletin Open 1:1.
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Jan P.A.M. Bogers, Peter F.J. Schulte, Theo G. Broekman, Peter Moleman & Lieuwe de Haan. (2018) Dose reduction of high-dose first-generation antipsychotics or switch to ziprasidone in long-stay patients with schizophrenia: A 1-year double-blind randomized clinical trial. European Neuropsychopharmacology 28:9, pages 1024-1034.
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Ahmed Naguy & Mohamed Abu-Zeid. (2017) The oft-times overlooked “pharmacologic” relapse in schizophrenia. Australasian Psychiatry 25:2, pages 201-202.
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Konstantinos N. Fountoulakis, Xenia Gonda, Melina Siamouli, Katerina Moutou, Zoe Nitsa, Brian E. Leonard & Siegfried Kasper. (2017) Higher than recommended dosages of antipsychotics in male patients with schizophrenia are associated with increased depression but no major neurocognitive side effects: Results of a cross-sectional pilot naturalistic study. Progress in Neuro-Psychopharmacology and Biological Psychiatry 75, pages 113-119.
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Lourdes Rodriguez del Barrio, Céline Cyr, Lisa Benisty & Pierrette Richard. (2013) Gaining Autonomy & Medication Management (GAM): new perspectives on well-being, quality of life and psychiatric medication. Ciência & Saúde Coletiva 18:10, pages 2879-2887.
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Herbert Y. Meltzer. (2013) Update on Typical and Atypical Antipsychotic Drugs. Annual Review of Medicine 64:1, pages 393-406.
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Ann M. Mortimer. (2018) Using clozapine in clinical practice. Advances in Psychiatric Treatment 17:4, pages 256-265.
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Matthias J. Müller. (2011) Clinical Practice Associated with a Switch from and to Ziprasidone during Routine Inpatient Treatment of Patients with Schizophrenia. Schizophrenia Research and Treatment 2011, pages 1-7.
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G. Remington & S. Kapur. (2010) Antipsychotic Dosing: How Much but also How Often?. Schizophrenia Bulletin 36:5, pages 900-903.
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