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Pedro Mondejar-Lopez, Maria Dolores Pastor-Vivero, Manuel Sanchez-Solis & Amparo Escribano. (2017) Cystic fibrosis treatment: targeting the basic defect. Expert Opinion on Orphan Drugs 5:2, pages 181-192.
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Irene Brusa, Elvira Sondo, Emanuela Pesce, Valeria Tomati, Dario Gioia, Federico Falchi, Beatrice Balboni, Jose Antonio Ortega Martínez, Marina Veronesi, Elisa Romeo, Natasha Margaroli, Maurizio Recanatini, Stefania Girotto, Nicoletta Pedemonte, Marinella Roberti & Andrea Cavalli. (2023) Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5. Journal of Medicinal Chemistry 66:14, pages 9797-9822.
Crossref
Crossref
Gerald Litwack. 2022. Human Biochemistry. Human Biochemistry
607
645
.
Indiwari Gopallawa & Robert J Lee. (2020) Targeting the phosphoinositide-3-kinase/protein kinase B pathway in airway innate immunity. World Journal of Biological Chemistry 11:2, pages 30-51.
Crossref
Crossref
Catherine Rang, Tom Kotsimbos & John Wilson. 2020. Cystic Fibrosis - Heterogeneity and Personalized Treatment. Cystic Fibrosis - Heterogeneity and Personalized Treatment.
Ioanna Loukou, Maria Moustaki, Marina Plyta & Konstantinos Douros. (2020) Longitudinal changes in lung function following initiation of lumacaftor/ivacaftor combination. Journal of Cystic Fibrosis 19:4, pages 534-539.
Crossref
Crossref
Dumin Yuan, Zhiyuan Ma, Biguang Tuo, Taolang Li & Xuemei Liu. (2020) Physiological Significance of Ion Transporters and Channels in the Stomach and Pathophysiological Relevance in Gastric Cancer. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-10.
Crossref
Crossref
Bianka Farkas, Hedvig Tordai, Rita Padányi, Attila Tordai, János Gera, Gábor Paragi & Tamás Hegedűs. (2019) Discovering the chloride pathway in the CFTR channel. Cellular and Molecular Life Sciences 77:4, pages 765-778.
Crossref
Crossref
Xiaoli Xu, Huimin Huang, Xiangyi Yin, Hongmei Fang & Xiaoyue Shen. (2020) Effect of lentivirus-mediated CFTR overexpression on oxidative stress injury and inflammatory response in the lung tissue of COPD mouse model. Bioscience Reports 40:1.
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Crossref
Zhiyuan Ma, Dumin Yuan, Xiaoming Cheng, Biguang Tuo, Xuemei Liu & Taolang Li. (2020) Function of ion transporters in maintaining acid-base homeostasis of the mammary gland and the pathophysiological role in breast cancer. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318:1, pages R98-R111.
Crossref
Crossref
Iwona Pranke, Anita Golec, Alexandre Hinzpeter, Aleksander Edelman & Isabelle Sermet-Gaudelus. (2019) Emerging Therapeutic Approaches for Cystic Fibrosis. From Gene Editing to Personalized Medicine. Frontiers in Pharmacology 10.
Crossref
Crossref
Brice Hoffmann, Ahmad Elbahnsi, Pierre Lehn, Jean-Luc Décout, Fabio Pietrucci, Jean-Paul Mornon & Isabelle Callebaut. (2018) Combining theoretical and experimental data to decipher CFTR 3D structures and functions. Cellular and Molecular Life Sciences 75:20, pages 3829-3855.
Crossref
Crossref
Valentina Corradi, Ruo-Xu Gu, Paola Vergani & D. Peter Tieleman. (2018) Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR. Biophysical Journal 114:8, pages 1751-1754.
Crossref
Crossref
Richmond Muimo, Hani MM Alothaid & Anil Mehta. (2018) NM23 proteins: innocent bystanders or local energy boosters for CFTR?. Laboratory Investigation 98:3, pages 272-282.
Crossref
Crossref
Cindy L. Vnencak-Jones & D. Hunter Best. 2018. Principles and Applications of Molecular Diagnostics. Principles and Applications of Molecular Diagnostics
125
189
.
Gerald Litwack. 2018. Human Biochemistry. Human Biochemistry
553
589
.
Jhuma Das, Andrei A. Aleksandrov, Liying Cui, Lihua He, John R. Riordan & Nikolay V. Dokholyan. (2017) Transmembrane helical interactions in the CFTR channel pore. PLOS Computational Biology 13:6, pages e1005594.
Crossref
Crossref
Alexander Negoda, Yassine El Hiani, Elizabeth A. Cowley & Paul Linsdell. (2017) Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel. Biochimica et Biophysica Acta (BBA) - Biomembranes 1859:5, pages 1049-1058.
Crossref
Crossref
Paul Linsdell. (2016) Architecture and functional properties of the CFTR channel pore. Cellular and Molecular Life Sciences 74:1, pages 67-83.
Crossref
Crossref
Isabelle Callebaut, Brice Hoffmann, Pierre Lehn & Jean-Paul Mornon. (2016) Molecular modelling and molecular dynamics of CFTR. Cellular and Molecular Life Sciences 74:1, pages 3-22.
Crossref
Crossref
Thida Ong & Bonnie W. Ramsey. (2016) New Therapeutic Approaches to Modulate and Correct Cystic Fibrosis Transmembrane Conductance Regulator. Pediatric Clinics of North America 63:4, pages 751-764.
Crossref
Crossref
F. QIAN, L. LIU, Z. LIU & C. LU. (2016) The Pore Architecture of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Revealed by Co-Mutation in Pore-Forming Transmembrane Regions. Physiological Research, pages 505-515.
Crossref
Crossref
Xiaolong Gao & Tzyh-Chang Hwang. (2016) Spatial positioning of CFTR’s pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway. Journal of General Physiology 147:5, pages 407-422.
Crossref
Crossref
Yassine El Hiani, Alexander Negoda & Paul Linsdell. (2015) Cytoplasmic pathway followed by chloride ions to enter the CFTR channel pore. Cellular and Molecular Life Sciences 73:9, pages 1917-1925.
Crossref
Crossref
Paul Linsdell. (2016) Anion conductance selectivity mechanism of the CFTR chloride channel. Biochimica et Biophysica Acta (BBA) - Biomembranes 1858:4, pages 740-747.
Crossref
Crossref
Markus A. Seeger, Enrica Bordignon & Michael Hohl. 2016. ABC Transporters - 40 Years on. ABC Transporters - 40 Years on
65
84
.
Paul Linsdell. 2017. Protein Reviews. Protein Reviews
13
32
.
Khaled Khoufache. (2015) The vectorial transport of salts and water is crucial for respiratory epithelial cell lines. Respiratory Research 16:1.
Crossref
Crossref
George M. Solomon, Susan G. Marshall, Bonnie W. Ramsey & Steven M. Rowe. (2015) Breakthrough therapies: Cystic fibrosis (CF) potentiators and correctors. Pediatric Pulmonology 50:S40, pages S3-S13.
Crossref
Crossref
Valentina Corradi, Paola Vergani & D. Peter Tieleman. (2015) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Journal of Biological Chemistry 290:38, pages 22891-22906.
Crossref
Crossref
Paul Linsdell. (2015) Interactions between permeant and blocking anions inside the CFTR chloride channel pore. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:7, pages 1573-1590.
Crossref
Crossref
Yassine El Hiani & Paul Linsdell. (2015) Functional Architecture of the Cytoplasmic Entrance to the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore. Journal of Biological Chemistry 290:25, pages 15855-15865.
Crossref
Crossref
Hussein N. Rubaiy & Paul Linsdell. (2015) Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore. The Journal of Physiological Sciences 65:3, pages 233-241.
Crossref
Crossref
Jean-Paul Mornon, Brice Hoffmann, Slavica Jonic, Pierre Lehn & Isabelle Callebaut. (2014) Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics. Cellular and Molecular Life Sciences 72:7, pages 1377-1403.
Crossref
Crossref
Xiaolong Gao & Tzyh-Chang Hwang. (2015) Localizing a gate in CFTR. Proceedings of the National Academy of Sciences 112:8, pages 2461-2466.
Crossref
Crossref
Peying Fong. 2015. Hormones and Transport Systems. Hormones and Transport Systems
33
62
.
Yassine El HianiPaul Linsdell. (2014) Conformational changes opening and closing the CFTR chloride channel: Insights from cysteine scanning mutagenesis. Biochemistry and Cell Biology 92:6, pages 481-488.
Crossref
Crossref
Feng Qian, Tao Li, Fei Yang & Lian Liu. (2014) Stoichiometry and novel gating mechanism within the cystic fibrosis transmembrane conductance regulator channel. Experimental Physiology 99:12, pages 1611-1623.
Crossref
Crossref
Paul Linsdell. (2014) State-dependent blocker interactions with the CFTR chloride channel: implications for gating the pore. Pflügers Archiv - European Journal of Physiology 466:12, pages 2243-2255.
Crossref
Crossref
Steven D. BroadbentWuyang WangPaul Linsdell. (2014) Interaction between 2 extracellular loops influences the activity of the cystic fibrosis transmembrane conductance regulator chloride channel. Biochemistry and Cell Biology 92:5, pages 390-396.
Crossref
Crossref
Yassine El Hiani & Paul Linsdell. (2014) Metal Bridges Illuminate Transmembrane Domain Movements during Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel. Journal of Biological Chemistry 289:41, pages 28149-28159.
Crossref
Crossref
Yiting Wang, Joe A. Wrennall, Zhiwei Cai, Hongyu Li & David N. Sheppard. (2014) Understanding how cystic fibrosis mutations disrupt CFTR function: From single molecules to animal models. The International Journal of Biochemistry & Cell Biology 52, pages 47-57.
Crossref
Crossref