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Research Article

Mercapturic Acids, Protein Adducts, and DNA Adducts as Biomarkers of Electrophilic Chemicals

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Pages 271-306 | Published online: 25 Sep 2008

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G. Sabbioni, O. Sepai, H. Norppa, H. Yan, A. Hirvonen, Y. Zheng, H. Järventaus, B. Bäck, L. R. Brooks, S. H. Warren, D. M. Demarini & Y. Y. Liu. (2007) Comparison of biomarkers in workers exposed to 2,4,6-trinitrotoluene. Biomarkers 12:1, pages 21-37.
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Mustafa Erat, Halis Sakiroglu & Mehmet Ciftci. (2003) Purification and Characterization of Glutathione Reductase from Bovine Erythrocytes. Preparative Biochemistry & Biotechnology 33:4, pages 283-300.
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Lars W. Wormhoudt, Jan N. M. Commandeur & Nico P. E. Vermeulen. (1999) Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic Metabolism and Toxicity. Critical Reviews in Toxicology 29:1, pages 59-124.
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J. C. L. Erve, M.L. Deinzer & D.J. Reed. (1996) Reaction of Human Hemoglobin Toward the Alkylating Agent S-(2-Chloroethyl)Glutathione. Journal of Toxicology and Environmental Health 49:2, pages 127-143.
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L. L. De Zwart, R. C. A. Hermanns, J. H. N. Meerman, J. N. M. Commandeur & N. P. E. Vermeulen. (1996) Disposition in rat of [2-3H]-trans-4-hydroxy-2,3-nonenal, a product of lipid peroxidation. Xenobiotica 26:10, pages 1087-1100.
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Nancy B. Hopf & Silvia Fustinoni. 2001. Patty's Industrial Hygiene. Patty's Industrial Hygiene 1 62 .
Stacey L. Konkle, Kristina M. Zierold, Kira C. Taylor, Daniel W. Riggs & Aruni Bhatnagar. (2020) National secular trends in ambient air volatile organic compound levels and biomarkers of exposure in the United States. Environmental Research 182, pages 108991.
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Douglas E. Stack, John A. Conrad & Bejan Mahmud. (2018) Structural Identification and Kinetic Analysis of the in Vitro Products Formed by Reaction of Bisphenol A-3,4-quinone with N -Acetylcysteine and Glutathione . Chemical Research in Toxicology 31:2, pages 81-87.
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Mengyao Zhao, Pengpu Wang, Daotong Li, Jin Shang, Xiaosong Hu & Fang Chen. (2017) Protection against neo-formed contaminants (NFCs)-induced toxicity by phytochemicals. Food and Chemical Toxicology 108, pages 392-406.
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Gabriele Sabbioni & Robert J. Turesky. (2016) Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future. Chemical Research in Toxicology 30:1, pages 332-366.
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Fang Xie, Jaime D’Agostino, Xin Zhou & Xinxin Ding. (2013) Bioactivation of the Nasal Toxicant 2,6-Dichlorobenzonitrile: An Assessment of Metabolic Activity in Human Nasal Mucosa and Identification of Indicators of Exposure and Potential Toxicity. Chemical Research in Toxicology 26:3, pages 388-398.
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Peta A. Neale, Alice Antony, Michael E. Bartkow, Maria José Farré, Anna Heitz, Ina Kristiana, Janet Y. M. Tang & Beate I. Escher. (2012) Bioanalytical Assessment of the Formation of Disinfection Byproducts in a Drinking Water Treatment Plant. Environmental Science & Technology 46:18, pages 10317-10325.
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Thomas W. Kensler, Derek Ng, Steven G. Carmella, Menglan Chen, Lisa P. Jacobson, Alvaro Muñoz, Patricia A. Egner, Jian Guo Chen, Geng Sun Qian, Tao Yang Chen, Jed W. Fahey, Paul Talalay, John D. Groopman, Jian-Min Yuan & Stephen S. Hecht. (2012) Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis 33:1, pages 101-107.
Crossref
Ernest Hodgson. 2012. Pesticide Biotransformation and Disposition. Pesticide Biotransformation and Disposition 179 193 .
Wolfgang Dekant & Spiridon Vamvakas. 2000. Ullmann's Encyclopedia of Industrial Chemistry. Ullmann's Encyclopedia of Industrial Chemistry.
Wolfgang Dekant & Spiridon Vamvakas. 2003. Ullmann's Encyclopedia of Industrial Chemistry. Ullmann's Encyclopedia of Industrial Chemistry.
Elisabeth Eckert, Klaus Schmid, Barbara Schaller, Kerstin Hiddemann-Koca, Hans Drexler & Thomas Göen. (2011) Mercapturic acids as metabolites of alkylating substances in urine samples of German inhabitants. International Journal of Hygiene and Environmental Health 214:3, pages 196-204.
Crossref
Michèle Berode, Pierre‐Olivier Droz & Michel P. Guillemin. 2001. Patty's Industrial Hygiene. Patty's Industrial Hygiene 455 521 .
Mark P. Grillo. 2010. Biotransformation and Metabolite Elucidation of Xenobiotics. Biotransformation and Metabolite Elucidation of Xenobiotics 245 294 .
Gerhard Scherer, Michael Urban, Heinz-Werner Hagedorn, Richard Serafin, Shixia Feng, Sunil Kapur, Raheema Muhammad, Yan Jin, Mohamadi Sarkar & Hans-Juergen Roethig. (2010) Determination of methyl-, 2-hydroxyethyl- and 2-cyanoethylmercapturic acids as biomarkers of exposure to alkylating agents in cigarette smoke. Journal of Chromatography B 878:27, pages 2520-2528.
Crossref
Elisabeth Eckert, Hans Drexler & Thomas Göen. (2010) Determination of six hydroxyalkyl mercapturic acids in human urine using hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC–ESI-MS/MS). Journal of Chromatography B 878:27, pages 2506-2514.
Crossref
Jieyu Dai, Fan Zhang & Jiang Zheng. (2010) Detection of protein adduction derived from styrene oxide to cysteine residues by alkaline permethylation. Analytical Biochemistry 405:1, pages 73-81.
Crossref
Françoise Guéraud. 2010. Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications. Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications 117 135 .
Kevin William Hanley, Martin R. Petersen, Kenneth L. Cheever & Lian Luo. (2010) Bromide and N-acetyl-S-(n-propyl)-l-cysteine in urine from workers exposed to 1-bromopropane solvents from vapor degreasing or adhesive manufacturing. International Archives of Occupational and Environmental Health 83:5, pages 571-584.
Crossref
Robin M. Black. (2010) History and perspectives of bioanalytical methods for chemical warfare agent detection. Journal of Chromatography B 878:17-18, pages 1207-1215.
Crossref
Mark P. Grillo. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 42 .
Ernest Hodgson. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 961 968 .
Peter J. Boogaard. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
. (2009) <italic>N</italic>-Acetyl-<italic>S</italic>-(<italic>n</italic>-Propyl)-<sc>L</sc>-Cysteine in Urine from Workers Exposed to 1-Bromopropane in Foam Cushion Spray Adhesives. The Annals of Occupational Hygiene.
Crossref
Federico Maria Rubino, Marco Pitton, Daniela Di Fabio & Antonio Colombi. (2009) Toward an “ omic ” physiopathology of reactive chemicals: Thirty years of mass spectrometric study of the protein adducts with endogenous and xenobiotic compounds . Mass Spectrometry Reviews 28:5, pages 725-784.
Crossref
Mark P. Grillo. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook 655 696 .
Raymond Olsen, Steinar Øvrebø, Syvert Thorud, Elsa Lundanes, Yngvar Thomassen, Tyge Greibrokk & Paal Molander. (2008) Sensitive determination of a glyoxal–DNA adduct biomarker candidate by column switching capillary liquid chromatography electrospray ionization mass spectrometry. The Analyst 133:6, pages 802.
Crossref
Micaela C. Damsten, Jan N. M. Commandeur, Alex Fidder, Albert G. Hulst, Daan Touw, Daan Noort & Nico P. E. Vermeulen. (2007) Liquid Chromatography/Tandem Mass Spectrometry Detection of Covalent Binding of Acetaminophen to Human Serum Albumin. Drug Metabolism and Disposition 35:8, pages 1408-1417.
Crossref
J.P. Teixeira, J. Gaspar, J. Roma-Torres, S. Silva, C. Costa, J. Roach, O. Mayan, J. Rueff & P.B. Farmer. (2007) Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: Possible influence of genetic polymorphism of drug-metabolising enzymes. Toxicology 237:1-3, pages 58-64.
Crossref
A.P. Freidig, S. Dekkers, M. Verwei, E. Zvinavashe, J.G.M. Bessems & J.J.M. van de Sandt. (2007) Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds. Toxicology Letters 170:3, pages 214-222.
Crossref
James D. Daly, Colleen M. O’Hehir & George M. Frame. (2007) A sensitive method for quantitation of β-lyase metabolites of sulfur mustard as 1,1′-sulfonylbis[2-(methylthio)ethane] (SBMTE) in human urine by isotope dilution liquid chromatography–positive ion-electrospray-tandem mass spectrometry. Journal of Chromatography B 850:1-2, pages 120-127.
Crossref
Gerhard Scherer, Johannes Engl, Michael Urban, Gerhard Gilch, Dinamis Janket & Kirsten Riedel. (2007) Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany. Regulatory Toxicology and Pharmacology 47:2, pages 171-183.
Crossref
Masanori Ogawa, Tsunehiro Oyama, Toyohi Isse, Tetsunosuke Yamaguchi, Tomoe Murakami, Yoko Endo & Toshihiro Kawamoto. (2006) Hemoglobin Adducts as a Marker of Exposure to Chemical Substances, Especially PRTR Class I Designated Chemical Substances. Journal of Occupational Health 48:5, pages 314-328.
Crossref
Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan & Shu-Feng Zhou. (2006) Monitoring drug–protein interaction. Clinica Chimica Acta 365:1-2, pages 9-29.
Crossref
Carrie L. Young, Adrian R. Woolfitt, Lisa G. McWilliams, Hercules Moura, Anne E. Boyer & John R. Barr. (2005) Survey of albumin purification methods for the analysis of albumin-organic toxicant adducts by liquid chromatography-electrospray ionization-tandem mass spectrometry. PROTEOMICS 5:18, pages 4973-4979.
Crossref
Gabriele Sabbioni, Yu-Ying Liu, Huifang Yan & Ovnair Sepai. (2005) Hemoglobin adducts, urinary metabolites and health effects in 2,4,6-trinitrotoluene exposed workers. Carcinogenesis 26:7, pages 1272-1279.
Crossref
John Timbrell. 2005. Metabonomics in Toxicity Assessment. Metabonomics in Toxicity Assessment 27 74 .
Wolfgang Dekant & Spiridon Vamvakas. 2000. Ullmann's Encyclopedia of Industrial Chemistry. Ullmann's Encyclopedia of Industrial Chemistry.
M.Carmen Nóvoa-Valiñas, Marcos Pérez-López & M.Julia Melgar-Riol. (2004) Hepatic glutathione S-transferases from lamprey (Petromyzom marinus): purification and characterization. Biochemical Systematics and Ecology 32:2, pages 169-178.
Crossref
Hilmi Orhan, Nico P.E Vermeulen, Cornelis Tump, Herman Zappey & John H.N Meerman. (2004) Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography–tandem mass spectrometry as non-invasive biomarkers for oxidative damage. Journal of Chromatography B 799:2, pages 245-254.
Crossref
Alexandra Lafaye, Christophe Junot, B�atrice Ramounet-Le Gall, Paul Fritsch, Jean-Claude Tabet & Eric Ezan. (2003) Metabolite profiling in rat urine by liquid chromatography/electrospray ion trap mass spectrometry. Application to the study of heavy metal toxicity. Rapid Communications in Mass Spectrometry 17:22, pages 2541-2549.
Crossref
Shufeng Zhou. (2003) Separation and detection methods for covalent drug–protein adducts. Journal of Chromatography B 797:1-2, pages 63-90.
Crossref
Jürgen Angerer, Albert W. Rettenmeier & Gabriele Sabbioni. 2002. Biological Monitoring. Biological Monitoring 5 34 .
M. Törnqvist, C. Fred, J. Haglund, H. Helleberg, B. Paulsson & P. Rydberg. (2002) Protein adducts: quantitative and qualitative aspects of their formation, analysis and applications. Journal of Chromatography B 778:1-2, pages 279-308.
Crossref
Peter J. Boogaard. (2002) Use of haemoglobin adducts in exposure monitoring and risk assessment. Journal of Chromatography B 778:1-2, pages 309-322.
Crossref
Vera Fiserova-Bergerova & Jaroslav Mraz. 2001. Patty's Industrial Hygiene. Patty's Industrial Hygiene.
Daniel G Mascher, Hermann J Mascher, Gerhard Scherer & E.R Schmid. (2001) High-performance liquid chromatographic–tandem mass spectrometric determination of 3-hydroxypropylmercapturic acid in human urine. Journal of Chromatography B: Biomedical Sciences and Applications 750:1, pages 163-169.
Crossref
Ernest Hodgson. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 583 587 .
Rachel I.M. van Haaften, Chris T.A. Evelo, Guido R.M.M. Haenen & Aalt Bast. (2001) α-Tocopherol Inhibits Human Glutathione S-Transferase π. Biochemical and Biophysical Research Communications 280:3, pages 631-633.
Crossref
Jürgen Angerer, Albert W. Rettenmeier & Gabriele Sabbioni. 2000. Biological Monitoring. Biological Monitoring 5 34 .
L H Lash, J C Parker & C S Scott. (2000) Modes of action of trichloroethylene for kidney tumorigenesis.. Environmental Health Perspectives 108:suppl 2, pages 225-240.
Crossref
Janeck J. Scott-Fordsmand & Jason M. Weeks. 2000. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology 117 159 .
Jan L. Vansteenhouse, Judith S. Prescott & Steven A. Barker. (2000) Identification of the 1-cyano-3,4-epithiobutane-derived urinary mercapturic acidn-acetyl-s-(4-cyano-2-thio-1-butyl)-cysteine in male fischer 344 rats. Journal of Applied Toxicology 20:1, pages 1-10.
Crossref
E Ardévol, C Minguillón, G Garcia, ME Serra, CA Gonzalez, L Alvarez, R Eritja & A Lafuente. (1999) Environmental tobacco smoke interference in the assessment of the health impact of a municipal waste incinerator on children through urinary thioether assay. Public Health 113:6, pages 295-298.
Crossref
Wolfgang Völkel, Axel Pähler & Wolfgang Dekant. (1999) Gas chromatography–negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins. Journal of Chromatography A 847:1-2, pages 35-46.
Crossref
Andreas P. Freidig, Henk J. M. Verhaar & Joop L. M. Hermens. (1999) Quantitative structure-property relationships for the chemical reactivity of acrylates and methacrylates. Environmental Toxicology and Chemistry 18:6, pages 1133-1139.
Crossref
Maarten F.C.M Knapen, Petra L.M Zusterzeel, Wilbert H.M Peters & Eric A.P Steegers. (1999) Glutathione and glutathione-related enzymes in reproduction. European Journal of Obstetrics & Gynecology and Reproductive Biology 82:2, pages 171-184.
Crossref
Loeckie L de Zwart, John H.N Meerman, Jan N.M Commandeur & Nico P.E Vermeulen. (1999) Biomarkers of free radical damage. Free Radical Biology and Medicine 26:1-2, pages 202-226.
Crossref
Christian H. Lindh & Bo A.G. Jönsson. (1998) Human Hemoglobin Adducts Following Exposure to Hexahydrophthalic Anhydride and Methylhexahydrophthalic Anhydride. Toxicology and Applied Pharmacology 153:2, pages 152-160.
Crossref
Wolfgang Völkel, Marion Friedewald, Elke Lederer, Axel Pähler, Jean Parker & Wolfgang Dekant. (1998) Biotransformation of Perchloroethene: Dose-Dependent Excretion of Trichloroacetic Acid, Dichloroacetic Acid, andN-acetyl-S-(trichlorovinyl)-l-Cysteine in Rats and Humans after Inhalation. Toxicology and Applied Pharmacology 153:1, pages 20-27.
Crossref
John A. Timbrell. (1998) Biomarkers in toxicology. Toxicology 129:1, pages 1-12.
Crossref
C.H Lindh & B.A.G Jönsson. (1998) Quantification method of human hemoglobin adducts from hexahydrophthalic anhydride and methylhexahydrophthalic anhydride. Journal of Chromatography B: Biomedical Sciences and Applications 710:1-2, pages 81-90.
Crossref
Siv M. Osterman-Golkar, Owen Moss, Arden James, Matthew S. Bryant, Max Turner & James A. Bond. (1998) Epoxybutene–Hemoglobin Adducts in Rats and Mice: Dose Response for Formation and Persistence During and Following Long-Term Low-Level Exposure to Butadiene. Toxicology and Applied Pharmacology 150:1, pages 166-173.
Crossref
Josef Gut. 1998. Diversification in Toxicology — Man and Environment. Diversification in Toxicology — Man and Environment 3 17 .
Marianne Möller, Dietrich Henschler & Gabriele Sabbioni. (2005) Synthesis and Spectroscopic Characterization of 4‐Chlorophenyl Isocyanate (= 1‐chloro‐4‐isocyanatobenzene) Adducts with Amino Acids as Potential Dosimeters for the Biomonitoring of Isocyanate Exposure. Helvetica Chimica Acta 81:5-8, pages 1254-1263.
Crossref
B M de Rooij, P J Boogaard, J N Commandeur, N J van Sittert & N P Vermeulen. (1997) Allylmercapturic acid as urinary biomarker of human exposure to allyl chloride.. Occupational and Environmental Medicine 54:9, pages 653-661.
Crossref
G. Scherer & E. Richter. (2016) Biomonitoring exposure to environmental tobacco smoke (ETS): A critical reappraisal. Human & Experimental Toxicology 16:8, pages 449-459.
Crossref
Ben M de Rooij, Pieter J Boogaard, Jan N.M Commandeur & Nico P.E Vermeulen. (1997) 3-Chloro-2-hydroxypropylmercapturic acid and α-chlorohydrin as biomarkers of occupational exposure to epichlorohydrin. Environmental Toxicology and Pharmacology 3:3, pages 175-185.
Crossref
Christa H. Oberth & A. Daniel Jonescor. (1997) Fragmentation of protonated thioether conjugates of acrolein using low collision energies. Journal of the American Society for Mass Spectrometry 8:7, pages 727-736.
Crossref
Ron van der Oost, Eric Vindimian, Paul J. van den Brink, Karel Satumalay, Henk Heida & Nico P.E. Vermeulen. (1997) Biomonitoring aquatic pollution with feral eel (Anguilla anguilla). III. Statistical analyses of relationships between contaminant exposure and biomarkers. Aquatic Toxicology 39:1, pages 45-75.
Crossref
Ron van der Oost, Anders Goksøyr, Malin Celander, Henk Heida & Nico P.E. Vermeulen. (1996) Biomonitoring of aquatic pollution with feral eel (Anguilla anguilla) II. Biomarkers: pollution-induced biochemical responses. Aquatic Toxicology 36:3-4, pages 189-222.
Crossref
Luigi Perbellini. (2006) From “Occupational Medicine” to “Occupational Health”. Journal of Occupational Health 38:4, pages 201-204.
Crossref
Alan R. Boobis. (1996) Interindividual variability in metabolic activation in humans in vivo. Environmental Toxicology and Pharmacology 2:2-3, pages 161-163.
Crossref
Ben M. De Rooij, Jan N.M. Commandeur, Jane R. Ramcharan, Hilda C.P. Schuilenburg, Ben L.M. Van Baar & Nico P.E. Vermeulen. (1996) Identification and quantitative determination of 3-chloro-2-hydroxypropylmercapturic acid and α-chlorohydrin in urine of rats treated with epichlorohydrin. Journal of Chromatography B: Biomedical Sciences and Applications 685:2, pages 241-250.
Crossref
Ulrich Ewers & Roland Suchenwirth. (1996) Expositionsabschätzung: Human-Biomonitoring vs. ModellrechnungenExposure and risk assessment — Health risks associated with human exposure to toxic substances: Human biomonitoring vs. model calculations. Umweltwissenschaften und Schadstoff-Forschung 8:4, pages 213-220.
Crossref
Gabriele Sabbioni, Jinfeng Wei & Yu-Ying Liu. (1996) Determination of hemoglobin adducts in workers exposed to 2,4,6-trinitrotoluene. Journal of Chromatography B: Biomedical Sciences and Applications 682:2, pages 243-248.
Crossref
D.G. Lindsay. (1996) Dietary contribution to genotoxic risk and its control. Food and Chemical Toxicology 34:4, pages 423-431.
Crossref
Pier Giuseppe Ciattini, Enrico Morera & Giorgio Ortar. (1995) A new, palladium-catalyzed synthesis of aromatic mercapturic acid derivatives. Tetrahedron Letters 36:23, pages 4133-4136.
Crossref
Jan H.T.M. Ploemen, Lars W. Wormhoudt, Ben van Ommen, Jan N.M. Commandeur, Nico P.E. Vermeulen & Peter J. van Bladeren. (1995) Polymorphism in the glutathione conjugation activity of human erythrocytes towards ethylene dibromide and 1,2-epoxy-3-(p-nitrophenoxy)-propane. Biochimica et Biophysica Acta (BBA) - General Subjects 1243:3, pages 469-476.
Crossref
Josef Gut, Urs Christen, Nora Frey, Valeria Koch & Daniel Stoffler. (1995) Molecular mimicry in halothane hepatitis: Biochemical and structural characterization of lipoylated autoantigens. Toxicology 97:1-3, pages 199-224.
Crossref
M F Ferreira Junior, S Tas, M dell'Omo, G Goormans, J P Buchet & R Lauwerys. (1994) Determinants of benzo(a)pyrenediol epoxide adducts to haemoglobin in workers exposed to polycyclic aromatic hydrocarbons.. Occupational and Environmental Medicine 51:7, pages 451-455.
Crossref
S. Fadlallah, M. Lachapelle, K. Krzystyniak, S. Cooper, F. Denizeau, F. Guertin & M. Fournier. (1994) O6-methylguanine-DNA adducts in rat lymphocytes after in vivo exposure to N-nitrosodimethylamine (NDMA). International Journal of Immunopharmacology 16:7, pages 583-591.
Crossref
Ronnie M Lawrence. (1994) Synthesis of pentafluorophenylthiohydantoin derivatives of adducts formed with dl-valine by acrylonitrile and cyanoethylene oxide. Tetrahedron Letters 35:22, pages 3767-3770.
Crossref
C. Viau, M. Mercier & O. Blondin. (1993) Measurement of hemoglobin and albumin adducts of benzo(a)pyrenediolepoxide and their rate of elimination in the female Sprague-Dawley rat. Archives of Toxicology 67:7, pages 468-472.
Crossref

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