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Critical Reviews in Biochemistry and Molecular Biology Volume 45, 2010 - Issue 3
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Review Article

Insights into the MCM functional mechanism: lessons learned from the archaeal MCM complex

Aaron S. BrewsterMolecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
&
Xiaojiang S. ChenMolecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USACorrespondence[email protected]
Pages 243-256 | Received 09 Dec 2009, Accepted 08 Apr 2010, Published online: 04 May 2010

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Matthew L Bochman. (2014) Roles of DNA helicases in the maintenance of genome integrity. Molecular & Cellular Oncology 1:3.
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Patricia Pérez-Arnaiz, Ambika Dattani, Victoria Smith & Thorsten Allers. (2020) Haloferax volcanii —a model archaeon for studying DNA replication and repair . Open Biology 10:12.
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Lori M. Kelman, William B. O’Dell & Zvi Kelman. (2020) Unwinding 20 Years of the Archaeal Minichromosome Maintenance Helicase. Journal of Bacteriology 202:6.
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Sihwa Joo, Bong H Chung, Mina Lee & Tai H Ha. (2019) Ring-shaped replicative helicase encircles double-stranded DNA during unwinding. Nucleic Acids Research 47:21, pages 11344-11354.
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Qihong Huang, Sohail Ahmad, Binyuan Zhai & Yulong Shen. 2019. Helicases from All Domains of Life. Helicases from All Domains of Life 19 38 .
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Kelly M. Schermerhorn, Nathan Tanner, Zvi Kelman & Andrew F. Gardner. (2016) High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases. Nucleic Acids Research 44:18, pages 8764-8771.
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Luca Pellegrini & Alessandro Costa. (2016) New Insights into the Mechanism of DNA Duplication by the Eukaryotic Replisome. Trends in Biochemical Sciences 41:10, pages 859-871.
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Stephen P Bell & Karim Labib. (2016) Chromosome Duplication in Saccharomyces cerevisiae . Genetics 203:3, pages 1027-1067.
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Catarina A. Marques, Calvin Tiengwe, Leandro Lemgruber, Jeziel D. Damasceno, Alan Scott, Daniel Paape, Lucio Marcello & Richard McCulloch. (2016) Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation . Nucleic Acids Research 44:10, pages 4763-4784.
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Ferdos Abid Ali & Alessandro Costa. (2016) The MCM Helicase Motor of the Eukaryotic Replisome. Journal of Molecular Biology 428:9, pages 1822-1832.
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Gretchen Meinke, Paul J. Phelan, Jong Shin, David Gagnon, Jacques Archambault, Andrew Bohm & Peter A. Bullock. (2016) Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains. PLOS Pathogens 12:1, pages e1005362.
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Xian Jessica Yu, William B. Greenleaf, Yemin Stanley Shi & Xiaojiang S. Chen. (2015) Mechanism of Subunit Coordination of an AAA+ Hexameric Molecular Nanomachine. Nanomedicine: Nanotechnology, Biology and Medicine 11:3, pages 531-541.
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Kasturi Goswami, Jasmine Arora & Swati Saha. (2015) Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus. Scientific Reports 5:1.
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Lori M. KelmanZvi Kelman. (2014) Archaeal DNA Replication. Annual Review of Genetics 48:1, pages 71-97.
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Christoph Wiedemann, Oliver Ohlenschl?ger, Barbara Medagli, Silvia Onesti & Matthias G?rlach. (2013) 1H,?15N and 13C chemical shift assignments for the winged helix domains of two archeal MCM C-termini. Biomolecular NMR Assignments 8:2, pages 357-360.
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Susan Krueger, Jae-Ho Shin, Joseph E. Curtis, Kenneth A. Rubinson & Zvi Kelman. (2014) The solution structure of full-length dodecameric MCM by SANS and molecular modeling. Proteins: Structure, Function, and Bioinformatics 82:10, pages 2364-2374.
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Yang Fu, Ian M. Slaymaker, Junfeng Wang, Ganggang Wang & Xiaojiang S. Chen. (2014) The 1.8-? Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament. Journal of Molecular Biology 426:7, pages 1512-1523.
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Simon K. W. Lam, Xiaoli Ma, Tina L. Sing, Brian H. Shilton, Christopher J. Brandl & Megan J. Davey. (2013) The PS1 Hairpin of Mcm3 Is Essential for Viability and for DNA Unwinding In Vitro. PLoS ONE 8:12, pages e82177.
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Melania S. Strycharska, Ernesto Arias-Palomo, Artem Y. Lyubimov, Jan P. Erzberger, Valerie L. O’Shea, Carlos J. Bustamante & James M. Berger. (2013) Nucleotide and Partner-Protein Control of Bacterial Replicative Helicase Structure and Function. Molecular Cell 52:6, pages 844-854.
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Alessandro CostaIris V. HoodJames M. Berger. (2013) Mechanisms for Initiating Cellular DNA Replication. Annual Review of Biochemistry 82:1, pages 25-54.
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Gretchen Meinke, Paul J. Phelan, Celia J. Harrison & Peter A. Bullock. (2013) Analysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral Assembly. Journal of Virology 87:5, pages 2923-2934.
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Zhuo LiLori M. KelmanZvi Kelman. (2013) Thermococcus kodakarensis DNA replication . Biochemical Society Transactions 41:1, pages 332-338.
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Ivar Ilves, Nele Tamberg & Michael R. Botchan. (2012) Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex. Proceedings of the National Academy of Sciences 109:33, pages 13163-13170.
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Calvin Tiengwe, Lucio Marcello, Helen Farr, Catarina Gadelha, Richard Burchmore, J. David Barry, Stephen D. Bell & Richard McCulloch. (2012) Identification of ORC1/CDC6-Interacting Factors in Trypanosoma brucei Reveals Critical Features of Origin Recognition Complex Architecture. PLoS ONE 7:3, pages e32674.
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Kira S Makarova, Eugene V Koonin & Zvi Kelman. (2012) The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes. Biology Direct 7:1, pages 7.
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Ian M. Slaymaker & Xiaojiang S. Chen. 2012. The Eukaryotic Replisome: a Guide to Protein Structure and Function. The Eukaryotic Replisome: a Guide to Protein Structure and Function 89 111 .
Miao Pan, Thomas J. Santangelo, Zhuo Li, John N. Reeve & Zvi Kelman. (2011) Thermococcus kodakarensis encodes three MCM homologs but only one is essential. Nucleic Acids Research 39:22, pages 9671-9680.
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S. Krueger, J.-H. Shin, S. Raghunandan, J.E. Curtis & Z. Kelman. (2011) Atomistic Ensemble Modeling and Small-Angle Neutron Scattering of Intrinsically Disordered Protein Complexes: Applied to Minichromosome Maintenance Protein. Biophysical Journal 101:12, pages 2999-3007.
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Brian W. Graham, Grant D. Schauer, Sanford H. Leuba & Michael A. Trakselis. (2011) Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding. Nucleic Acids Research 39:15, pages 6585-6595.
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Li Phing LiewStephen D. Bell. (2011) The interplay of DNA binding, ATP hydrolysis and helicase activities of the archaeal MCM helicase. Biochemical Journal 436:2, pages 409-414.
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Nozomi Sakakibara, Rajesh Kasiviswanathan & Zvi Kelman. (2011) Mutational analysis of conserved aspartic acid residues in the Methanothermobacter thermautotrophicus MCM helicase. Extremophiles 15:2, pages 245-252.
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Zhuo Li, Thomas J. Santangelo, Ľubomíra Čuboňová, John N. Reeve & Zvi Kelman. (2010) Affinity Purification of an Archaeal DNA Replication Protein Network. mBio 1:5.
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Aaron S Brewster, Ian M Slaymaker, Samir A Afif & Xiaojiang S Chen. (2010) Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding. BMC Molecular Biology 11:1.
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Michael Botchan & James Berger. (2010) DNA Replication: Making Two Forks from One Prereplication Complex. Molecular Cell 40:6, pages 860-861.
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Nozomi Sakakibara, Rajesh Kasiviswanathan & Zvi Kelman. (2010) Different Residues on the Surface of the Methanothermobacter thermautotrophicus MCM Helicase Interact with Single- and Double-Stranded DNA . Archaea 2010, pages 1-8.
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