Citations (212)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Cagla Kayabasi, Sunde Yilmaz Susluer, Tugce Balci Okcanoglu, Besra Ozmen Yelken, Zeynep Mutlu, Bakiye Goker Bagca, Cansu Caliskan Kurt, Guray Saydam, Cenk Durmuskahya, Husniye Kayalar, Ahmet Ozbilgin, Cigir Biray Avci & Cumhur Gunduz. (2022) Origanum Sipyleum Methanol Extract in Combination with Ponatinib Shows Synergistic anti-Leukemic Activities on Chronic Myeloid Leukemia Cells. Nutrition and Cancer 74:10, pages 3679-3691.
Read now
Read now
Ana M. Rincón & Fernando Monje-Casas. (2020) A guiding torch at the poles: the multiple roles of spindle microtubule-organizing centers during cell division. Cell Cycle 19:12, pages 1405-1421.
Read now
Read now
Shin-Young Kim, Sun-Yi Hyun & Young-Joo Jang. (2019) Dephosphorylation of Plk1 occurs through PP2A-B55/ENSA/Greatwall pathway during mitotic DNA damage recovery. Cell Cycle 18:10, pages 1154-1167.
Read now
Read now
Ryan J. Davis, Jherek Swanger, Bridget T. Hughes & Bruce E. Clurman. (2017) The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation. Molecular and Cellular Biology 37:8.
Read now
Read now
Articles from other publishers (208)
Kevin Qin, Michael Yu, Jiaming Fan, Hongwei Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Connie Chen, Yonghui Wang, Annie Wang, Zander Schwartz, Jeffrey Hong, Lily Song, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin H. Ho, Jason Strelzow, Russell R. Reid, Tong-Chuan He & Lewis L. Shi. (2024) Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk. Genes & Diseases 11:1, pages 103-134.
Crossref
Crossref
Benjamin W. French, Rajat Kaul, Jerrin George, Steven T. Haller, David J. Kennedy & Deepa Mukundan. (2023) A Case Series of Potential Pediatric Cyanotoxin Exposures Associated with Harmful Algal Blooms in Northwest Ohio. Infectious Disease Reports 15:6, pages 726-734.
Crossref
Crossref
Matteo Mazzella, Keegan Walker, Christina Cormier, Michael Kapanowski, Albi Ishmakej, Azeem Saifee, Yashvardhan Govind & G. Rasul Chaudhry. (2023) Regulation of self-renewal and senescence in primitive mesenchymal stem cells by Wnt and TGFβ signaling. Stem Cell Research & Therapy 14:1.
Crossref
Crossref
Riya Thapa, Obaid Afzal, Asif Ahmad Bhat, Ahsas Goyal, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Sami I Alzarea, Imran Kazmi, Sachin Kumar Singh, Kamal Dua, Lakshmi Thangavelu & Gaurav Gupta. (2023) New horizons in lung cancer management through ATR/CHK1 pathway modulation. Future Medicinal Chemistry.
Crossref
Crossref
Xianming ZhouQian XuWangzi LiNianguo DongColin StomberskiGoutham NarlaZhiyong Lin. (2023) Protein Phosphatase 2A Activation Promotes Heart Transplant Acceptance in Mice. Transplantation.
Crossref
Crossref
Qizhi Geng, Yue‐Yu Kong, Weizhe Li, Jianhao Zhang, Haoli Ma, Yuhang Zhang, Lin‐Tai Da, Yan Zhao & Hai‐Ning Du. (2023) Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression. Advanced Science 10:30.
Crossref
Crossref
Yunqing Li, NingJing Liang, Tingting Tang, Zhijian Zheng, Muting Chen, Jiao Mo, Ning Zhang, Simi Liao, Yu Lei, Yijie Wu, Chunhua Lan, Huan Ding, Bingxin Du, Mei Feng, Xinhang Wang, Xiaoying Li, Yue Huang, Cailing Lu, Shen Tang & Xiyi Li. (2023) Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition. Food and Chemical Toxicology 179, pages 113986.
Crossref
Crossref
Ben Li, Shanglong Liu, Yuan Gao, Longbo Zheng & Yun Lu. (2023) Combined detection of SDC2/ADHFE1/PPP2R5C methylation in stool DNA for colorectal cancer screening. Journal of Cancer Research and Clinical Oncology 149:12, pages 10241-10253.
Crossref
Crossref
Faezeh Tolue Ghasaban, Amirhosein Maharati, Amir Sadra Zangouei, Alireza Zangooie & Meysam Moghbeli. (2023) MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers. Cancer Cell International 23:1.
Crossref
Crossref
Colette Dehay & Henry Kennedy. 2023. Neocortical Neurogenesis in Development and Evolution. Neocortical Neurogenesis in Development and Evolution
63
81
.
Behzad Heidari, Dugassa Nemie-Feyissa & Cathrine Lillo. (2023) Distinct Clades of Protein Phosphatase 2A Regulatory B’/B56 Subunits Engage in Different Physiological Processes. International Journal of Molecular Sciences 24:15, pages 12255.
Crossref
Crossref
Tian-Yi Jiang, Xiao-Wen Cui, Tian-Mei Zeng, Yu-Fei Pan, Yun-Kai LinXiao-fan Feng, Ye-Xiong Tan, Zhen-gang Yuan, Li-Wei Dong & Hong-Yang Wang. (2023) PTEN deficiency facilitates gemcitabine efficacy in cancer by modulating the phosphorylation of PP2Ac and DCK. Science Translational Medicine 15:704.
Crossref
Crossref
Philippe Pierre Robichaud, Nadia Bouhamdani, Eugénie Girouard, Emily Biden & Mouna Ben Amor. (2023) A pigmentary manifestation associated with PPP2R5D-related neurodevelopmental disorder: a case report and review of literature. Bulletin of the National Research Centre 47:1.
Crossref
Crossref
Alexander Yu. Vertyshev, Ilya R. Akberdin & Fedor A. Kolpakov. (2023) Numerous Trigger-like Interactions of Kinases/Protein Phosphatases in Human Skeletal Muscles Can Underlie Transient Processes in Activation of Signaling Pathways during Exercise. International Journal of Molecular Sciences 24:13, pages 11223.
Crossref
Crossref
Kirill A. Konovalov, Cheng-Guo Wu, Yunrui Qiu, Vijaya Kumar Balakrishnan, Pankaj Singh Parihar, Michael S. O’Connor, Yongna Xing & Xuhui Huang. (2023) Disease mutations and phosphorylation alter the allosteric pathways involved in autoinhibition of protein phosphatase 2A. The Journal of Chemical Physics 158:21.
Crossref
Crossref
Rahul S. Patil, Anita Kovacs-Kasa, Boris A. Gorshkov, David J. R. Fulton, Yunchao Su, Robert K. Batori & Alexander D. Verin. (2023) Serine/Threonine Protein Phosphatases 1 and 2A in Lung Endothelial Barrier Regulation. Biomedicines 11:6, pages 1638.
Crossref
Crossref
Yingzheng Wang, Pawat Pattarawat, Jiyang Zhang, Eunchong Kim, Delong Zhang, Mingzhu Fang, Elizabeth A. Jannaman, Ye Yuan, Saurabh Chatterjee, Ji-Yong Julie Kim, Geoffrey I. Scott, Qiang Zhang & Shuo Xiao. (2023) Effects of Cyanobacterial Harmful Algal Bloom Toxin Microcystin-LR on Gonadotropin-Dependent Ovarian Follicle Maturation and Ovulation in Mice. Environmental Health Perspectives 131:6.
Crossref
Crossref
Rita A. Avelar, Amy J. Armstrong, Gracie Carvette, Riya Gupta, Noah Puleo, Jose A. Colina, Peronne Joseph, Alexander M. Sobeck, Caitlin M. O'Connor, Brynne Raines, Agharnan Gandhi, Michele L. Dziubinski, Daniel S. Ma, Kimberly Resnick, Sareena Singh, Kristine Zanotti, Christa Nagel, Steven Waggoner, Daffyd G. Thomas, Stephanie L. Skala, Junran Zhang, Goutham Narla & Analisa DiFeo. (2023) Small-Molecule–Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death. Molecular Cancer Therapeutics 22:5, pages 599-615.
Crossref
Crossref
Nora Oyama, Pieter Vaneynde, Sara Reynhout, Emily M Pao, Andrew Timms, Xiao Fan, Kimberly Foss, Rita Derua, Veerle Janssens, Wendy Chung & Ghayda M Mirzaa. (2023)
Clinical, neuroimaging and molecular characteristics of
PPP2R5D
-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype–phenotype analysis
. Journal of Medical Genetics 60:5, pages 511-522.
Crossref
Crossref
Jerry Vriend & Thomas Klonisch. (2022) Genes of the Ubiquitin Proteasome System Qualify as Differential Markers in Malignant Glioma of Astrocytic and Oligodendroglial Origin. Cellular and Molecular Neurobiology 43:4, pages 1425-1452.
Crossref
Crossref
Christina Fevga, Christelle Tesson, Ana Carreras Mascaro, Thomas Courtin, Riaan van Coller, Salma Sakka, Federico Ferraro, Nouha Farhat, Soraya Bardien, Mariem Damak, Jonathan Carr, Mélanie Ferrien, Valerie Boumeester, Jasmijn Hundscheid, Nicola Grillenzoni, Irini A Kessissoglou, Demy J S Kuipers, Marialuisa Quadri, Yves Agid, Mathieu Anheim, Michel Borg, Alexis Brice, Emmanuel Broussolle, Jean-Christophe Corvol, Philippe Damier, Luc Defebvre, Alexandra Dürr, Franck Durif, Jean Luc Houeto, Paul Krack, Stephan Klebe, Suzanne Lesage, Ebba Lohmann, Maria Martinez, Graziella Mangone, Louise-Laure Mariani, Pierre Pollak, Olivier Rascol, François Tison, Christine Tranchant, Marc Vérin, François Viallet, Marie Vidailhet, Ebba Lohmann, Murat Emre, Hasmet Hanagasi, Basar Bilgic, Bedia Marangozog lu, Mustapha Benmahdjoub, Mohammed Arezki, Sofiane A Bouchetara, Traki Benhassine, Meriem Tazir, Mouna Ben Djebara, Riadh Gouider, Sawssan Ben Romdhan, Chokri Mhiri, Ahmed Bouhouche, Vincenzo Bonifati, Wim Mandemakers, Anneke J A Kievit, Agnita J W Boon, Joaquim J Ferreira, Leonor Correia Guedes, Murat Emre, Hasmet A Hanagasi, Basar Bilgic, Zeynep Tufekcioglu, Bulent Elibol, Okan Dog.u, Murat Gultekin, Hsin F Chien, Egberto Barbosa, Laura Bannach Jardim, Carlos R M Rieder, Hsiu-Chen Chang, Chin-Song Lu, Yah-Huei Wu-Chou, Tu-Hsueh Yeh, Leonardo Lopiano, Cristina Tassorelli, Claudio Pacchetti, Cristoforo Comi, Francesco Raudino, Laura Bertolasi, Michele Tinazzi, Alberto Bonizzato, Carlo Ferracci, Roberto Marconi, Marco Guidi, Marco Onofrj, Astrid Thomas, Nicola Vanacore, Giuseppe Meco, Edito Fabrizio, Giovanni Fabbrini, Alfredo Berardelli, Fabrizio Stocchi, Laura Vacca, Paolo Barone, Marina Picillo, Giuseppe De Michele, Chiara Criscuolo, Michele De Mari, Claudia Dell’Aquila, Giovanni Iliceto, Vincenzo Toni, Giorgio Trianni, Valeria Saddi, Gianni Cossu, Maurizio Melis, Jean-Christophe Corvol, Chokri Mhiri, Bassem A Hassan, Guido J Breedveld, Suzanne Lesage, Wim Mandemakers, Alexis Brice & Vincenzo Bonifati. (2023)
PTPA
variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability
. Brain 146:4, pages 1496-1510.
Crossref
Crossref
Gustavo H. Marin, Samuel Murail, Laura Andrini, Marcela Garcia, Severine Loisel, Pierre Tuffery & Angelita Rebollo. (2023) In Silico and In Vivo Studies of a Tumor-Penetrating and Interfering Peptide with Antitumoral Effect on Xenograft Models of Breast Cancer. Pharmaceutics 15:4, pages 1180.
Crossref
Crossref
Melissa Roths, Alyssa D. Freestone, Tori E. Rudolph, Alyona Michael, Lance H. Baumgard & Joshua T. Selsby. (2023) Environment-induced heat stress causes structural and biochemical changes in the heart. Journal of Thermal Biology 113, pages 103492.
Crossref
Crossref
Zhen Zhang, William E Samsa, Yanyan De, Fan Zhang, Ofer Reizes, Alexandru Almasan & Zihua Gong. (2023) HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair. Nucleic Acids Research 51:5, pages 2238-2256.
Crossref
Crossref
Heather C. Murray, Kasey Miller, Joshua S. Brzozowski, Richard G.S. Kahl, Nathan D. Smith, Sean J. Humphrey, Matthew D. Dun & Nicole M. Verrills. (2023) Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia. Molecular & Cellular Proteomics 22:3, pages 100503.
Crossref
Crossref
Yuan Fu, Xiaofan Jia, Jinwei Yuan, Yuting Yang, Teng Zhang, Qiujing Yu, Jun Zhou & Ting Wang. (2023) Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates. Developmental Cell 58:5, pages 398-415.e7.
Crossref
Crossref
Shuai Zhao, Ziqi Fan, Xinyi Zhang, Zheyu Li, Ting Shen, Kaicheng Li, Yaping Yan, Yunfeng Yuan, Jiali Pu, Jun Tian, Zhirong Liu, Yanxing Chen & Baorong Zhang. (2022) Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice. Neurotherapeutics 20:2, pages 452-463.
Crossref
Crossref
María José López-Grueso, Carmen Alicia Padilla, José Antonio Bárcena & Raquel Requejo-Aguilar. (2022) Deficiency of Parkinson’s Related Protein DJ-1 Alters Cdk5 Signalling and Induces Neuronal Death by Aberrant Cell Cycle Re-entry. Cellular and Molecular Neurobiology 43:2, pages 757-769.
Crossref
Crossref
Luo-Luo Xu, Hui-Xiang Su, Pang-Bo Li & Hui-Hua Li. (2023) Ursolic Acid Ameliorates Myocardial Ischaemia/Reperfusion Injury by Improving Mitochondrial Function via Immunoproteasome-PP2A-AMPK Signalling. Nutrients 15:4, pages 1049.
Crossref
Crossref
Kuriko Doi, Hiroto Takeuchi & Hiroshi Sakurai. (2022)
PP2A‐B55
and its adapter proteins
IER2
and
IER5
regulate the activity of
RB
family proteins and the expression of cell cycle‐related genes
. The FEBS Journal 290:3, pages 745-762.
Crossref
Crossref
Wen-Hsuan Chang, Yinzhe Liu, Emma A. Hammes, Kirsten L. Bryant, Richard A. Cerione & Marc A. Antonyak. (2023) Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin. Journal of Biological Chemistry 299:2, pages 102842.
Crossref
Crossref
Heriati Sitosari, Ikkei Morimoto, Yao Weng, Yilin Zheng, Yoko Fukuhara, Mika Ikegame & Hirohiko Okamura. (2023) Inhibition of protein phosphatase 2A by okadaic acid induces translocation of nucleocytoplasmic O-GlcNAc transferase. Biochemical and Biophysical Research Communications 646, pages 50-55.
Crossref
Crossref
HONGMEI WU, DI LI, YUANYUAN HUANG, RUYUAN LIU & XIAONIAN ZHU. (2023) Research progress of protein phosphatase 2A in cellular autophagy. BIOCELL 47:3, pages 485-491.
Crossref
Crossref
Jacques Robert. 2023. Ciblage Thérapeutique en Oncologie. Ciblage Thérapeutique en Oncologie
81
86
.
Laura Cucinotta, Alessia Filippone, Giovanna Casili, Marika Lanza, Valentina Bova, Anna Paola Capra, Raffaella Giuffrida, Cristina Colarossi, Dorotea Sciacca, Irene Paterniti, Salvatore Cuzzocrea, Michela Campolo & Emanuela Esposito. (2022) The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors. International Journal of Molecular Sciences 23:24, pages 15717.
Crossref
Crossref
Ahmad Abu Qubo, Jamil Numan, Juan Snijder, Maria Padilla, John H.M. Austin, Kathleen M. Capaccione, Monica Pernia, Jean Bustamante, Timothy O'Connor & Mary M. Salvatore. (2023) Idiopathic pulmonary fibrosis and lung cancer: future directions and challenges. Breathe 18:4, pages 220147.
Crossref
Crossref
Tingting Gan, Xing Liu, Xia Chen, Yichao Shi & Wenbin Wang. (2023) Okadaic Acid Inhibits Protein Phosphatases to Suppress Spermatogonial Cell Proliferation. Biology Bulletin 49:S2, pages S12-S19.
Crossref
Crossref
Terrance J. HaanenIIIIII, Caitlin M. O'Connor & Goutham Narla. (2022) Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules. Journal of Biological Chemistry 298:12, pages 102656.
Crossref
Crossref
Cheng Cheng, Yuanxia Cai, Xiaowei Liu, Yangkun Wu, Qianqian Cheng, Yeming Wu & Zhixiang Wu. (2022) KHSRP modulated cell proliferation and cell cycle via regulating PPP2CA and p27 expression in Wilms tumor. Cellular Signalling 100, pages 110447.
Crossref
Crossref
Amrita Sule, Sarah E. Golding, Syed F. Ahmad, James Watson, Mostafa H. Ahmed, Glen E. Kellogg, Tytus Bernas, Sean Koebley, Jason C. Reed, Lawrence F. Povirk & Kristoffer Valerie. (2022) ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response. Cellular and Molecular Life Sciences 79:12.
Crossref
Crossref
Jiaxu Wang, Meng Li, Jing Zhang, Qing Gao, Zhaoxi Ding & Jinhao Sun. (2022) Paliperidone alleviates MK-801-induced damage to prefrontal cortical neurons via the PP2A/PTEN pathway. Journal of Affective Disorders 317, pages 265-277.
Crossref
Crossref
Zijing Zong, Yao Dang, Yang Zhang, Liqin Yu, Chunsheng Liu & Jianghua Wang. (2022) Promotion effect on liver tumor progression of microcystin-LR at environmentally relevant levels in female krasV12 transgenic zebrafish. Aquatic Toxicology 252, pages 106313.
Crossref
Crossref
Bence Hajdú, Marianna Holczer, Gergely Horváth, Gábor Szederkényi & Orsolya Kapuy. (2022) Fine-Tuning of mTORC1-ULK1-PP2A Regulatory Triangle Is Crucial for Robust Autophagic Response upon Cellular Stress. Biomolecules 12:11, pages 1587.
Crossref
Crossref
Peng Wang, Wentao Li, Ziyi Liu, Xiaoyun He, Rong Lan, Yufang Liu & Mingxing Chu. (2022) Analysis of the Association of Two SNPs in the Promoter Regions of the PPP2R5C and SLC39A5 Genes with Litter Size in Yunshang Black Goats. Animals 12:20, pages 2801.
Crossref
Crossref
Thomas Kokot & Maja Köhn. (2022) Emerging insights into serine/threonine-specific phosphoprotein phosphatase function and selectivity. Journal of Cell Science 135:19.
Crossref
Crossref
Yu Zhang, Xingchen Wang, Anqi Li, Yanhui Guan, Peibo Shen, Yingqian Ni & Xiuzhen Han. (2022) PP2A regulates metastasis and vasculogenic mimicry formation via PI3K/AKT/ZEB1 axis in non-small cell lung cancers. Journal of Pharmacological Sciences 150:2, pages 56-66.
Crossref
Crossref
Song Gao, Liping Shan, Mo Zhang, Yan Wang, Xi Zhan, Yalei Yin, Zhonghao Jiang, Xinyi Tao, Xinyu Li, Mingliang Ye & Yang Liu. (2022) Inhibition of PP2A by LB100 sensitizes bladder cancer cells to chemotherapy by inducing p21 degradation. Cellular Oncology.
Crossref
Crossref
Boyi Hu, Shuyu Hao, Yazhou Miao, Yuxuan Deng, Jing Wang, Hong Wan, Shaodong Zhang, Nan Ji & Jie Feng. (2022) Inhibiting PP2A Upregulates B7-H3 Expression and Potentially Increases the Sensitivity of Malignant Meningiomas to Immunotherapy by Proteomics. Pathology and Oncology Research 28.
Crossref
Crossref
Kathrin Jäger, Juliane Mensch, Maria Elisabeth Grimmig, Bruno NeunerKerstin GorzelniakSeval Türkmen, Ilja Demuth, Alexander Hartmann, Christiane Hartmann, Felix Wittig, Anje SporbertAndreas Hermann, Georg Fuellen, Steffen Möller & Michael Walter. (2022) A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts. Science Advances 8:33.
Crossref
Crossref
Dasheng Cai, Yue Zhao & Fang Yu. (2022) Puerarin ameliorates acute lung injury by modulating NLRP3 inflammasome-induced pyroptosis. Cell Death Discovery 8:1.
Crossref
Crossref
Massimiliano Secchi, Camilla Lodola, Anna Garbelli, Silvia Bione & Giovanni Maga. (2022) DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective. Cancers 14:15, pages 3820.
Crossref
Crossref
Xiaoni Shi, Jing Wang, Xinxin Zhang, Shaoqi Yang, Wei Luo, Sha Wang, Jie Huang, Mengling Chen, Yusi Cheng & Jie Chao. (2022) GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis. Cell & Bioscience 12:1.
Crossref
Crossref
Yitong Li, Vijaya Kumar Balakrishnan, Michael Rowse, Cheng-Guo Wu, Anastasia Phoebe Bravos, Vikash K Yadav, Ylva Ivarsson, Stefan Strack, Irina V Novikova & Yongna Xing. (2022) Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition. eLife 11.
Crossref
Crossref
Nicole S. York, Juan C. Sanchez-Arias, Alexa C. H. McAdam, Joel E. Rivera, Laura T. Arbour & Leigh Anne Swayne. (2022) Mechanisms underlying the role of ankyrin-B in cardiac and neurological health and disease. Frontiers in Cardiovascular Medicine 9.
Crossref
Crossref
Jean-Marie Sontag, Diana Schuhmacher, Goce Taleski, Anthony Jordan, Sarah Khan, Alexander Hoffman, Rey J. Gomez, Matthew D. Mazalouskas, Steven K. Hanks, Benjamin W. Spiller, Estelle Sontag & Brian E. Wadzinski. (2022) A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation. Journal of Biological Chemistry 298:8, pages 102248.
Crossref
Crossref
Daniel Moreno-Andrés, Anuk Bhattacharyya, Anja Scheufen & Johannes Stegmaier. (2022) LiveCellMiner: A new tool to analyze mitotic progression. PLOS ONE 17:7, pages e0270923.
Crossref
Crossref
Xinxing Pan, Zhe Geng, Jingyun Li, Xingxing Li, Mi Zhang, Xusu Wang, Yu Cong, Ke Huang, Juan Xu & Xuemei Jia. (2022) Peptide PDHPS1 Inhibits Ovarian Cancer Growth through Disrupting YAP Signaling. Molecular Cancer Therapeutics 21:7, pages 1160-1170.
Crossref
Crossref
Jitender Monga, Sharad Kumar Suthar, Deepak Rohila, Alex Joseph, Chetan Singh Chauhan & Manu Sharma. (2022) (+)-Cyanidan-3-ol inhibits epidermoid squamous cell carcinoma growth via inhibiting AKT/mTOR signaling through modulating CIP2A-PP2A axis. Phytomedicine 101, pages 154116.
Crossref
Crossref
Lilit Antonyan & Carl Ernst. (2022) Putative Roles of SETBP1 Dosage on the SET Oncogene to Affect Brain Development. Frontiers in Neuroscience 16.
Crossref
Crossref
Hyeon-Ah Do & Kwang-Hyun Baek. (2022) Protein phosphatase 2A regulated by USP7 is polyubiquitinated and polyneddylated. Oncology Reports 48:1.
Crossref
Crossref
David A. Cruz Walma, Zhuoyao Chen, Alex N. Bullock & Kenneth M. Yamada. (2022) Ubiquitin ligases: guardians of mammalian development. Nature Reviews Molecular Cell Biology 23:5, pages 350-367.
Crossref
Crossref
Laura Bownes, Raoud Marayati, Colin Quinn, Andee Beierle, Sara Hutchins, Janet Julson, Michael Erwin, Jerry Stewart, Elizabeth Mroczek-Musulman, Michael Ohlmeyer, Jamie Aye, Karina Yoon & Elizabeth Beierle. (2022) Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma. Cancers 14:8, pages 1952.
Crossref
Crossref
Paramesh Jangili, Na Kong, Ji Hyeon Kim, Jun Zhou, Haijun Liu, Xingcai Zhang, Wei Tao & Jong Seung Kim. (2022) DNA‐Damage‐Response‐Targeting Mitochondria‐Activated Multifunctional Prodrug Strategy for Self‐Defensive Tumor Therapy. Angewandte Chemie International Edition 61:16.
Crossref
Crossref
Paramesh Jangili, Na Kong, Ji Hyeon Kim, Jun Zhou, Haijun Liu, Xingcai Zhang, Wei Tao & Jong Seung Kim. (2022) DNA‐Damage‐Response‐Targeting Mitochondria‐Activated Multifunctional Prodrug Strategy for Self‐Defensive Tumor Therapy. Angewandte Chemie 134:16.
Crossref
Crossref
Chao Mei, Ze‐En Sun, Li‐Ming Tan, Jian‐Ping Gong, Xi Li & Zhao‐Qian Liu. (2022) eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response. Cell Proliferation 55:4.
Crossref
Crossref
Song Wu, Linlin Xie, Shaofei Cheng, Zhengyang Fan, Hongyang Sang & QianPing Li. (2022) UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling. Pathology - Research and Practice 232, pages 153762.
Crossref
Crossref
Osiris Germán Idelfonso-García, Brisa Rodope Alarcón-Sánchez, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Saúl Villa-Treviño, Pablo Muriel, Héctor Serrano, Julio Isael Pérez-Carreón & Jaime Arellanes-Robledo. (2022) Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies. Antioxidants 11:4, pages 670.
Crossref
Crossref
Xinhang Jiang, Wenxue Li, Mingxue Tan, Ping Guo, Xiaoling Liu, Xinhong Pan, Dianke Yu, Yaqin Pang, Daochuan Li, Qing Wang, Wen Chen & Liping Chen. (2022) Identification of miRNAs involved in liver injury induced by chronic exposure to cadmium. Toxicology 469, pages 153133.
Crossref
Crossref
Huai-Yu Qiao, Qi Zhang, Jia-Mei Wang, Jing-Yi Jiang, Ling-Yue Huyan, Jing Yan, Chao Li & Hua-Qin Wang. (2022) TRIM29 regulates the SETBP1/SET/PP2A axis via transcription factor VEZF1 to promote progression of ovarian cancer. Cancer Letters 529, pages 85-99.
Crossref
Crossref
Ugo Moens, Carla Prezioso & Valeria Pietropaolo. (2022) Functional Domains of the Early Proteins and Experimental and Epidemiological Studies Suggest a Role for the Novel Human Polyomaviruses in Cancer. Frontiers in Microbiology 13.
Crossref
Crossref
Kittisak Suanpan, Potjanee Srimanote, Pongsri Tongtawe, Onruedee Khantisitthiporn, Oratai Supasorn, Patthaya Rattanakomol & Jeeraphong Thanongsaksrikul. (2022) Transcriptome of human neuroblastoma SH-SY5Y cells in response to 2B protein of enterovirus-A71. Scientific Reports 12:1.
Crossref
Crossref
Shen Chen, Liping Chen, Lizhu Ye, Yue Jiang, Qiong Li, Haiyan Zhang, Rui Zhang, Huiyao Li, Dianke Yu, Rong Zhang, Yujie Niu, Qun Zhao, Jianhui Liu, Gangfeng Ouyang, Michael Aschner, Yuxin Zheng, Lihua Zhang, Wen Chen & Daochuan Li. (2022) PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury. Journal of Hazardous Materials 424, pages 127624.
Crossref
Crossref
Siriphorn Chimplee, Sittiruk Roytrakul, Suchada Sukrong, Theera Srisawat, Potchanapond Graidist & Kanyanatt Kanokwiroon. (2022) Anticancer Effects and Molecular Action of 7-α-Hydroxyfrullanolide in G2/M-Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cells. Molecules 27:2, pages 407.
Crossref
Crossref
Gema Lordén, Avery J. Lam, Megan K. Levings & Alexandra C. Newton. 2022. PI3K and AKT Isoforms in Immunity. PI3K and AKT Isoforms in Immunity
117
143
.
Eric Savier, Pierre Tuffery, Heriberto Bruzzoni-Giovanelli & Angelita Rebollo. 2022. Cell Penetrating Peptides. Cell Penetrating Peptides
413
427
.
Kyeong‐Min Kim & Won‐Gu Jang. (2021) NXNL1 negatively regulates osteoblast differentiation via GDF15‐induced PP2A Cα dependent manner in MC3T3‐E1 cells. BioFactors 48:1, pages 239-248.
Crossref
Crossref
Adrien Krug, Adriana Martinez-Turtos & Els Verhoeyen. (2021) Importance of T, NK, CAR T and CAR NK Cell Metabolic Fitness for Effective Anti-Cancer Therapy: A Continuous Learning Process Allowing the Optimization of T, NK and CAR-Based Anti-Cancer Therapies. Cancers 14:1, pages 183.
Crossref
Crossref
David Maria Hollenstein, Gabriela Gérecová, Natalie Romanov, Jessica Ferrari, Jiri Veis, Marion Janschitz, Reinhard Beyer, Christoph Schüller, Egon Ogris, Markus Hartl, Gustav Ammerer & Wolfgang Reiter. (2021) A phosphatase‐centric mechanism drives stress signaling response. EMBO reports 22:11.
Crossref
Crossref
Qian Zuo, Long Liao, Zi-Ting Yao, Ya-Ping Liu, Ding-Kang Wang, Shu-Jun Li, Xing-Feng Yin, Qing-Yu He & Wen-Wen Xu. (2021) Targeting PP2A with lomitapide suppresses colorectal tumorigenesis through the activation of AMPK/Beclin1-mediated autophagy. Cancer Letters 521, pages 281-293.
Crossref
Crossref
Timo T. Myöhänen, Freke Mertens, Susanna Norrbacka & Hengjing Cui. (2021) Deletion or inhibition of prolyl oligopeptidase blocks lithium‐induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A. Basic & Clinical Pharmacology & Toxicology 129:4, pages 287-296.
Crossref
Crossref
Kelly M. Girskis, Andrew B. Stergachis, Ellen M. DeGennaro, Ryan N. Doan, Xuyu Qian, Matthew B. Johnson, Peter P. Wang, Gabrielle M. Sejourne, M. Aurel Nagy, Elizabeth A. Pollina, André M.M. Sousa, Taehwan Shin, Connor J. Kenny, Julia L. Scotellaro, Brian M. Debo, Dilenny M. Gonzalez, Lariza M. Rento, Rebecca C. Yeh, Janet H.T. Song, Marc Beaudin, Jean Fan, Peter V. Kharchenko, Nenad Sestan, Michael E. Greenberg & Christopher A. Walsh. (2021) Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions. Neuron 109:20, pages 3239-3251.e7.
Crossref
Crossref
Yilu Xu, Lancheng Wei, Shen Tang, Qianqian Shi, Bin Wu, Xiaobo Yang, Yunfeng Zou, Xinhang Wang, Qingqing Ao, Ling Meng, Xuejing Wei, Ning Zhang, Yunqing Li, Chunhua Lan, Muting Chen, Xiyi Li & Cailing Lu. (2021) Regulation PP2Ac methylation ameliorating autophagy dysfunction caused by Mn is associated with mTORC1/ULK1 pathway. Food and Chemical Toxicology 156, pages 112441.
Crossref
Crossref
Michael P. Wilczek, Francesca J. Armstrong, Remi P. Geohegan, Colleen L. Mayberry, Jeanne K. DuShane, Benjamin L. King & Melissa S. Maginnis. (2021) The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes. Viruses 13:9, pages 1834.
Crossref
Crossref
Bo Sun, Fang-Jing Zhong, Cong Xu, Yi-Ming Li, Yan-Rong Zhao, Mo-Mo Cao & Lian-Yue Yang. (2021) Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation. Cell Death & Disease 12:9.
Crossref
Crossref
Seung-Hyeon Seok. (2021) Structural Insights into Protein Regulation by Phosphorylation and Substrate Recognition of Protein Kinases/Phosphatases. Life 11:9, pages 957.
Crossref
Crossref
Satyamaanasa Polubothu, Davide Zecchin, Lara Al-Olabi, Daniël A. Lionarons, Mark Harland, Stuart Horswell, Anna C. Thomas, Lilian Hunt, Nathan Wlodarchak, Paula Aguilera, Sarah Brand, Dale Bryant, Cristina Carrera, Hui Chen, Greg Elgar, Catherine A. Harwood, Michael Howell, Lionel Larue, Sam Loughlin, Jeff MacDonald, Josep Malvehy, Sara Martin Barberan, Vanessa Martins da Silva, Miriam Molina, Deborah Morrogh, Dale Moulding, Jérémie Nsengimana, Alan Pittman, Joan-Anton Puig-Butillé, Kiran Parmar, Neil J. Sebire, Stephen Scherer, Paulina Stadnik, Philip Stanier, Gemma Tell, Regula Waelchli, Mehdi Zarrei, Susana Puig, Véronique Bataille, Yongna Xing, Eugene Healy, Gudrun E. Moore, Wei-Li Di, Julia Newton-Bishop, Julian Downward & Veronica A. Kinsler. (2021) Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype. Genetics in Medicine 23:9, pages 1636-1647.
Crossref
Crossref
A. Khayachi, L. Schorova, M. Alda, G.A. Rouleau & A.J. Milnerwood. (2021) Posttranslational modifications & lithium’s therapeutic effect—Potential biomarkers for clinical responses in psychiatric & neurodegenerative disorders. Neuroscience & Biobehavioral Reviews 127, pages 424-445.
Crossref
Crossref
Zhixing Xu, Xi Chen, Ahmed M. Hegazy, Shudong Zhang, Xujie Liu, Jintao Tian, Jin Wu, Fengcai Shi, Lihua Li, Xiaoqun Niu & Jun Pu. (2021) Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells. Brain Research Bulletin 173, pages 14-21.
Crossref
Crossref
Yangjie Jia, Xia Wang, Yanyu Chen, Wenying Qiu, Wei Ge & Chao Ma. (2021) Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer’s Disease. Molecular Neurobiology 58:8, pages 4007-4027.
Crossref
Crossref
Roberta Squecco, Federica Pierucci, Eglantina Idrizaj, Alessia Frati, Elena Lenci, Catia Vicenti, Maria Chiara Iachini, Maria Martinesi, Rachele Garella, Maria Caterina Baccari, Fabio Francini & Elisabetta Meacci. (2021) Ceramide/protein phosphatase 2A axis is engaged in gap junction impairment elicited by PCB153 in liver stem-like progenitor cells. Molecular and Cellular Biochemistry 476:8, pages 3111-3126.
Crossref
Crossref
Majid Momeny, Tiina Arsiola & Jukka Westermarck. (2021) Cancer stem cell phosphatases. Biochemical Journal 478:14, pages 2899-2920.
Crossref
Crossref
Minsung Kang, Chijung Kim, Jiyeon Leem, Ye-hyun Kim, Young-ju Kwon, Yi Na Yoon, Chong Hak Chae, Jiyeon Ahn, Kwan-Young Jung, Jeong Su Oh & Jae-Sung Kim. (2021) Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and Oocytes. Pharmaceuticals 14:7, pages 647.
Crossref
Crossref
Priyanka Sandal, Chian Ju Jong, Ronald A. Merrill, Jianing Song & Stefan Strack. (2021) Protein phosphatase 2A – structure, function and role in neurodevelopmental disorders. Journal of Cell Science 134:13.
Crossref
Crossref
Jean-Paul Bryant, Adam Levy, John Heiss & Yeshavanth Kumar Banasavadi-Siddegowda. (2021) Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System. Cancers 13:12, pages 3087.
Crossref
Crossref
Marilynn Chow‐Castro, Shandee D Dixon & Joshua C Saldivar. (2021) Restraining CDK1–cyclin B activation: PP2A on the cUSP(7). The EMBO Journal 40:11.
Crossref
Crossref
Pragati & Surajit Sarkar. (2021)
Shaggy functions downstream of
dMyc
and their concurrent downregulation confers additive rescue against tau toxicity in
Drosophila
. BioFactors 47:3, pages 461-477.
Crossref
Crossref
Friederike Cuello, Friedrich W. Herberg, Konstantina Stathopoulou, Philipp Henning & Simon Diering. (2021) Regulation of Cardiac PKA Signaling by cAMP and Oxidants. Antioxidants 10:5, pages 663.
Crossref
Crossref
Tiziano Lottini, Jessica Iorio, Elena Lastraioli, Laura Carraresi, Claudia Duranti, Cesare Sala, Miriam Armenio, Ivo Noci, Serena Pillozzi & Annarosa Arcangeli. (2021) Transgenic mice overexpressing the LH receptor in the female reproductive system spontaneously develop endometrial tumour masses. Scientific Reports 11:1.
Crossref
Crossref
Jiahui Du, Junjun Jing, Shuo Chen, Yuan Yuan, Jifan Feng, Thach-Vu Ho, Prerna Sehgal, Jian Xu, Xinquan Jiang & Yang Chai. (2021) Arid1a regulates cell cycle exit of transit-amplifying cells by inhibiting the Aurka-Cdk1 axis in mouse incisor. Development 148:8.
Crossref
Crossref
Soeun Hwang, Min-Hee Kim & Chang-Woo Lee. (2021) Ssu72 Dual-Specific Protein Phosphatase: From Gene to Diseases. International Journal of Molecular Sciences 22:7, pages 3791.
Crossref
Crossref
Chit Tam, Shitao Rao, Mary Miu Yee Waye, Tzi Bun Ng & Chi Chiu Wang. (2021) Autophagy signals orchestrate chemoresistance of gynecological cancers. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:2, pages 188525.
Crossref
Crossref
Zhuolin Li, Yao Lin, Bizhen Cheng, Qiaoxin Zhang & Yingmu Cai. (2021) Identification and Analysis of Potential Key Genes Associated With Hepatocellular Carcinoma Based on Integrated Bioinformatics Methods. Frontiers in Genetics 12.
Crossref
Crossref
Michelle L. Swift, Kate Beishline, Samuel Flashner & Jane Azizkhan-Clifford. (2021) DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1. Cell Reports 34:11, pages 108840.
Crossref
Crossref
Alek S. Torres & Marina K. Holz. (2021) Unraveling the multifaceted nature of the nuclear function of mTOR. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:2, pages 118907.
Crossref
Crossref
Jun Hao, Xinpei Ci, Yong Wang, Stephen Yiu Chuen Choi, Sarah E. Sullivan, Hui Xue, Rebecca Wu, Xin Dong, Anne M. Haegert, Colin C. Collins, Dong Lin & Yuzhuo Wang. (2020)
GRB10
sustains
AR
activity by interacting with
PP2A
in prostate cancer cells
. International Journal of Cancer 148:2, pages 469-480.
Crossref
Crossref
Keira E. Mahoney, Jeffrey Shabanowitz & Donald F. Hunt. (2021) MHC Phosphopeptides: Promising Targets for Immunotherapy of Cancer and Other Chronic Diseases. Molecular & Cellular Proteomics 20, pages 100112.
Crossref
Crossref
Shima Shahbaz, Juan Jovel & Shokrollah Elahi. (2021) Differential transcriptional and functional properties of regulatory T cells in HIV‐infected individuals on antiretroviral therapy and long‐term non‐progressors. Clinical & Translational Immunology 10:5.
Crossref
Crossref
Rebecca S. Rivard, Julia M. Morris & Matthew J. Youngman. (2020) The PP2A/4/6 subfamily of phosphoprotein phosphatases regulates DAF-16 and confers resistance to environmental stress in postreproductive adult C. elegans. PLOS ONE 15:12, pages e0229812.
Crossref
Crossref
Xue Zhang, Wenmei Du, Junjie Zhang, Zhen Zou & Changchun Ruan. (2020) High-throughput profiling of diapause regulated genes from Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae). BMC Genomics 21:1.
Crossref
Crossref
Mohd Moin Khan, Tommi Välikangas, Meraj Hasan Khan, Robert Moulder, Ubaid Ullah, Santosh Dilip Bhosale, Elina Komsi, Umar Butt, Xi Qiao, Jukka Westermarck, Laura L. Elo & Riitta Lahesmaa. (2020) Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells. Current Research in Immunology 1, pages 10-22.
Crossref
Crossref
Hai Zheng, Yilun Qi, Shibin Hu, Xuan Cao, Congling Xu, Zhinang Yin, Xizi Chen, Yan Li, Weida Liu, Jie LiJiawei Wang, Gang Wei, Kaiwei Liang, Fei Xavier Chen & Yanhui Xu. (2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science 370:6520.
Crossref
Crossref
Maria Masnata, Shireen Salem, Aurelie de Rus Jacquet, Mehwish Anwer & Francesca Cicchetti. (2020) Targeting Tau to Treat Clinical Features of Huntington's Disease. Frontiers in Neurology 11.
Crossref
Crossref
Feng Li, David Kozono, Peter Deraska, Timothy Branigan, Connor Dunn, Xiao-Feng Zheng, Kalindi Parmar, Huy Nguyen, James DeCaprio, Geoffrey I. Shapiro, Dipanjan Chowdhury & Alan D. D’Andrea. (2020) CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress. Molecular Cell 80:3, pages 410-422.e6.
Crossref
Crossref
Li Zhang & Handong Wang. (2020) FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential. Brain Research Bulletin 164, pages 75-82.
Crossref
Crossref
Michael Plank, Marina Berti & Robbie Loewith. (2020) Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55. PROTEOMICS, pages 2000166.
Crossref
Crossref
Noé Rodríguez-Rodríguez, Iris K. Madera-Salcedo, J. Alejandro Cisneros-Segura, H. Benjamín García-González, Sokratis A. Apostolidis, Abril Saint-Martin, Marcela Esquivel-Velázquez, Tran Nguyen, Dámaris P. Romero-Rodríguez, George C. Tsokos, Jorge Alcocer-Varela, Florencia Rosetti & José C. Crispín. (2020) Protein phosphatase 2A B55β limits CD8+ T cell lifespan following cytokine withdrawal. Journal of Clinical Investigation 130:11, pages 5989-6004.
Crossref
Crossref
Jing Ding, Min Yu, Juncai Jiang, Yanbei Luo, Qian Zhang, Shengnan Wang, Fei Yang, Alei Wang, Lingxiao Wang, Mei Zhuang, Shan Wu, Qifang Zhang, Yong Xia & Deqin Lu. (2020) Angiotensin II Decreases Endothelial Nitric Oxide Synthase Phosphorylation via AT1R Nox/ROS/PP2A Pathway. Frontiers in Physiology 11.
Crossref
Crossref
Isha Nasa, Lauren E. Cressey, Thomas KruseEmil P. T. Hertz, Jiang GuiLee M. GravesJakob NilssonArminja N. Kettenbach. (2020) Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry. Science Signaling 13:648.
Crossref
Crossref
Fei Xie, Fei Li, Rui Li, Zongtao Liu, Jiawei Shi, Chao Zhang & Nianguo Dong. (2020) Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways. Life Sciences 257, pages 118086.
Crossref
Crossref
Iram Fatima, Amar B. Singh & Punita Dhawan. (2020) MASTL: A novel therapeutic target for Cancer Malignancy. Cancer Medicine 9:17, pages 6322-6329.
Crossref
Crossref
Yetunde Makinwa, Brian M. Cartwright, Phillip R. Musich, Zhengke Li, Himadri Biswas & Yue Zou. (2020) PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses. Frontiers in Cell and Developmental Biology 8.
Crossref
Crossref
Sahar Sarmasti Emami, Derek Zhang & Xiaolong Yang. (2020) Interaction of the Hippo Pathway and Phosphatases in Tumorigenesis. Cancers 12:9, pages 2438.
Crossref
Crossref
Iñigo Ayestaran, Ana Galhoz, Elmar Spiegel, Ben Sidders, Jonathan R. Dry, Frank Dondelinger, Andreas Bender, Ultan McDermott, Francesco Iorio & Michael P. Menden. (2020) Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens. Patterns 1:5, pages 100065.
Crossref
Crossref
Thomas Kruse, Sebastian Peter Gnosa, Isha Nasa, Dimitriya Hristoforova Garvanska, Jamin B Hein, Hieu Nguyen, Jacob Samsøe‐Petersen, Blanca Lopez‐Mendez, Emil Peter Thrane Hertz, Jeanette Schwarz, Hanna Sofia Pena, Denise Nikodemus, Marie Kveiborg, Arminja N Kettenbach & Jakob Nilsson. (2020) Mechanisms of site‐specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits. The EMBO Journal 39:13.
Crossref
Crossref
Jiyeon Seo & Mikyoung Park. (2019) Molecular crosstalk between cancer and neurodegenerative diseases. Cellular and Molecular Life Sciences 77:14, pages 2659-2680.
Crossref
Crossref
Veer Bhatt, Ke Shi, Daniel J. Salamango, Nicholas H. Moeller, Krishan K. Pandey, Sibes Bera, Heather O. Bohl, Fredy Kurniawan, Kayo Orellana, Wei Zhang, Duane P. Grandgenett, Reuben S. Harris, Anna C. Sundborger-Lunna & Hideki Aihara. (2020) Structural basis of host protein hijacking in human T-cell leukemia virus integration. Nature Communications 11:1.
Crossref
Crossref
Hiroki Akiyama, Yumi Iwasaki, Seiya Yamada, Hiroyuki Kamiguchi & Shin-ichi Sakakibara. (2020) Control of cell migration by the novel protein phosphatase-2A interacting protein inka2. Cell and Tissue Research 380:3, pages 527-537.
Crossref
Crossref
Raffaella Pippa, Silvia Boffo, Maria D. Odero & Antonio Giordano. (2019) Data mining analysis of the PP2A cell cycle axis in mesothelioma patients. Journal of Cellular Physiology 235:6, pages 5284-5292.
Crossref
Crossref
Chase H. Melick & Jenna L. Jewell. (2020) Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors. Biochemical Journal 477:10, pages 1847-1863.
Crossref
Crossref
Laura Saieva, Maria Magdalena Barreca, Chiara Zichittella, Maria Giulia Prado, Marco Tripodi, Riccardo Alessandro & Alice Conigliaro. (2020) Hypoxia-Induced miR-675-5p Supports β-Catenin Nuclear Localization by Regulating GSK3-β Activity in Colorectal Cancer Cell Lines. International Journal of Molecular Sciences 21:11, pages 3832.
Crossref
Crossref
Mi-Sun Lee, Jin Wan & Daniel Goldman. (2020) Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration. eLife 9.
Crossref
Crossref
Guan-Rong Lai, Yi-Fen Lee, Shian-Jang Yan & Huei-Ju Ting. (2020) Active vitamin D induces gene-specific hypomethylation in prostate cancer cells developing vitamin D resistance. American Journal of Physiology-Cell Physiology 318:5, pages C836-C847.
Crossref
Crossref
Bor Luen Tang. (2020) Could metformin be therapeutically useful in Huntington’s disease?. Reviews in the Neurosciences 31:3, pages 297-317.
Crossref
Crossref
Sara Marelli, James C Williamson, Anna V Protasio, Adi Naamati, Edward JD Greenwood, Janet E Deane, Paul J Lehner & Nicholas J Matheson. (2020) Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest. eLife 9.
Crossref
Crossref
Matthäus Mittasch, Vanna M. Tran, Manolo U. Rios, Anatol W. Fritsch, Stephen J. Enos, Beatriz Ferreira Gomes, Alec Bond, Moritz Kreysing & Jeffrey B. Woodruff. (2020) Regulated changes in material properties underlie centrosome disassembly during mitotic exit. Journal of Cell Biology 219:4.
Crossref
Crossref
Chian Ju Jong, Ronald A. Merrill, Emily M. Wilkerson, Laura E. Herring, Lee M. Graves & Stefan Strack. (2020) Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B′δ holoenzyme. Journal of Biological Chemistry 295:17, pages 5654-5668.
Crossref
Crossref
Xinru Wang, Dimitriya H Garvanska, Isha Nasa, Yumi Ueki, Gang Zhang, Arminja N Kettenbach, Wolfgang Peti, Jakob Nilsson & Rebecca Page. (2020) A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment. eLife 9.
Crossref
Crossref
Tianfeng Ma, Naifang Cao, Kele Chen, Hao Wang, Lihong Xu, Chun Xu & Pu Huang. (2019) Microcystin‐LR exposure disrupts the insulin signaling pathway in C2C12 mice muscle cell line. Environmental Toxicology 35:2, pages 194-202.
Crossref
Crossref
Reinis Svarcbahs, Maria Jäntti, Tommi Kilpeläinen, Ulrika H. Julku, Lauri Urvas, Saara Kivioja, Susanna Norrbacka & Timo T. Myöhänen. (2020) Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A. Pharmacological Research 151, pages 104558.
Crossref
Crossref
Maha El Taweel, Rania M. Gawdat & Rafaat Abdelfattah. (2019) Prognostic Impact of PPP2R5C Gene Expression in Adult Acute Myeloid Leukemia Patients with Normal Cytogenetics. Indian Journal of Hematology and Blood Transfusion 36:1, pages 37-46.
Crossref
Crossref
Harshita B. Saksena, Dhriti Singh, Manvi Sharma, Muhammed Jamsheer K.Sunita Jindal, Mohan Sharma, Archna Tiwari, Prakhar, Sanjay Singh Rawat & Ashverya Laxmi. 2020. Protein Phosphatases and Stress Management in Plants. Protein Phosphatases and Stress Management in Plants
103
123
.
Yolanda Moyano-Rodriguez & Ethel Queralt. (2019) PP2A Functions during Mitosis and Cytokinesis in Yeasts. International Journal of Molecular Sciences 21:1, pages 264.
Crossref
Crossref
Szu-Yuan Wu, Yu-Ching Wen, Chia-Chi Ku, Yi-Chieh Yang, Jyh-Ming Chow, Shun-Fa Yang, Wei-Jiunn Lee & Ming-Hsien Chien. (2019) Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses. Journal of Biomedical Science 26:1.
Crossref
Crossref
Kalina Wiatr, Piotr Piasecki, Łukasz Marczak, Paweł Wojciechowski, Małgorzata Kurkowiak, Rafał Płoski, Małgorzata Rydzanicz, Luiza Handschuh, Johannes Jungverdorben, Oliver Brüstle, Marek Figlerowicz & Maciej Figiel. (2019) Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional Changes, Shape the Molecular Pathogenesis in the Brain of Young Presymptomatic Ki91 SCA3/MJD Mouse. Molecular Neurobiology 56:12, pages 8168-8202.
Crossref
Crossref
Yan Xiong, Jianan Lan, Kaixin Huang, Yaruo Zhang, Lewei Zheng, Yanfeng Wang & Qifa Ye. (2019) PP2Ac upregulates PI3K-Akt signaling and induces hepatocyte apoptosis in liver donor after brain death. Apoptosis 24:11-12, pages 921-933.
Crossref
Crossref
Huijuan Chen, Jing Xu, Peixiao Wang, Qingming Shu, Lihong Huang, Jing Guo, Xuyi Zhang, Hongying Zhang, Ying Wang, Zhongyang Shen, Xinguo Chen & Qing Zhang. (2019) Protein phosphatase 2 regulatory subunit B''Alpha silencing inhibits tumor cell proliferation in liver cancer. Cancer Medicine 8:18, pages 7741-7753.
Crossref
Crossref
Soo Young Jun, Su-Jin Jeon, Ji-Yong Yoon, Jeong-Ju Lee, Hyang Ran Yoon, Min-Hyuk Choi, Debasish Halder, Kwangho Lee & Nam-Soon Kim. (2019) The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer. Scientific Reports 9:1.
Crossref
Crossref
Abbey L. Perl, Caitlin M. O’Connor, Pengyan Fa, Franklin Mayca Pozo, Junran Zhang, Youwei Zhang & Goutham Narla. (2019) Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45). Journal of Biological Chemistry 294:45, pages 17043-17059.
Crossref
Crossref
Cristina Sánchez-de-Diego, José Antonio Valer, Carolina Pimenta-Lopes, José Luis Rosa & Francesc Ventura. (2019) Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology. Biomolecules 9:10, pages 534.
Crossref
Crossref
Yan Tang, JungWoo Yang, Wang Zheng, Jingfeng Tang, Xing-Zhen Chen, Jianzheng Yang & Zuocheng Wang. (2019)
Polycystin-1 Inhibits Cell Proliferation through Phosphatase PP2A/B56
α
. BioMed Research International 2019, pages 1-8.
Crossref
Crossref
Soraya Játiva, Ines Calabria, Yolanda Moyano-Rodriguez, Patricia Garcia & Ethel Queralt. (2019) Cdc14 activation requires coordinated Cdk1-dependent phosphorylation of Net1 and PP2A–Cdc55 at anaphase onset. Cellular and Molecular Life Sciences 76:18, pages 3601-3620.
Crossref
Crossref
Wen-chao Yu, Hui-hao Chen, Yan-yan Qu, Chun-wei Xu, Chen Yang & Yan Liu. (2019) MicroRNA-221 promotes cisplatin resistance in osteosarcoma cells by targeting PPP2R2A. Bioscience Reports 39:7.
Crossref
Crossref
Jeanne K. DuShane & Melissa S. Maginnis. (2019) Human DNA Virus Exploitation of the MAPK-ERK Cascade. International Journal of Molecular Sciences 20:14, pages 3427.
Crossref
Crossref
Sonja Schötterl, Jennifer T. Miemietz, Elena I. Ilina, Naita M. Wirsik, Ingrid Ehrlich, Andrea Gall, Stephan M. Huber, Hans Lentzen, Michel Mittelbronn & Ulrike Naumann. (2019)
Mistletoe-Based Drugs Work in Synergy with Radio-Chemotherapy in the Treatment of Glioma
In Vitro
and
In Vivo
in Glioblastoma Bearing Mice
. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-17.
Crossref
Crossref
Da-Wei Lin, Benjamin P. Chung, Jia-Wei Huang, Xiaorong Wang, Lan Huang & Peter Kaiser. (2019) Microhomology-based CRISPR tagging tools for protein tracking, purification, and depletion. Journal of Biological Chemistry 294:28, pages 10877-10885.
Crossref
Crossref
Michiel Remmerie & Veerle Janssens. (2019) PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer. Frontiers in Oncology 9.
Crossref
Crossref
Karen I Lange, Aly Suleman & Martin Srayko. (2019)
Kinetochore Recruitment of the Spindle and Kinetochore-Associated (Ska) Complex Is Regulated by Centrosomal PP2A in
Caenorhabditis elegans
. Genetics 212:2, pages 509-522.
Crossref
Crossref
Ismail Suliman Elgenaidi & James Paul Spiers. (2019) Hypoxia modulates protein phosphatase 2A through HIF‐1α dependent and independent mechanisms in human aortic smooth muscle cells and ventricular cardiomyocytes. British Journal of Pharmacology 176:11, pages 1745-1763.
Crossref
Crossref
I.S. Elgenaidi & J.P. Spiers. (2019) Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target?. Pharmacology & Therapeutics 198, pages 68-89.
Crossref
Crossref
Jerry Vriend & Robert B. Tate. (2019) Differential Expression of Genes for Ubiquitin Ligases in Medulloblastoma Subtypes. The Cerebellum 18:3, pages 469-488.
Crossref
Crossref
Matthias Beyens, Timon Vandamme, Marc Peeters, Guy Van Camp & Ken Op de Beeck. (2019) Resistance to targeted treatment of gastroenteropancreatic neuroendocrine tumors. Endocrine-Related Cancer 26:3, pages R109-R130.
Crossref
Crossref
Peter Kubiniok, Brendan T. Finicle, Fanny Piffaretti, Alison N. McCracken, Michael Perryman, Stephen Hanessian, Aimee L. Edinger & Pierre Thibault. (2019) Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs. Molecular & Cellular Proteomics 18:3, pages 408-422.
Crossref
Crossref
Pushpendra Kumar Sahu & Raghuvir Singh Tomar. (2019) The natural anticancer agent cantharidin alters GPI-anchored protein sorting by targeting Cdc1-mediated remodeling in endoplasmic reticulum. Journal of Biological Chemistry 294:11, pages 3837-3852.
Crossref
Crossref
Ali Naderi. (2019) Molecular functions of brain expressed X-linked 2 (BEX2) in malignancies. Experimental Cell Research 376:2, pages 221-226.
Crossref
Crossref
Takumi Ueda, Yuri Kohama & Hiroshi Sakurai. (2019) IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. Cellular Signalling 55, pages 81-89.
Crossref
Crossref
Yuri Kohama, Megumi Saito, Mizue Yada & Hiroshi Sakurai. (2019) Regulation of the stability and activity of CDC25A and CDC25B by protein phosphatase PP2A and 14-3-3 binding. Cellular Signalling 54, pages 10-16.
Crossref
Crossref
Tim Sonntag, Jelena Ostojić, Joan M. Vaughan, James J. Moresco, Young-Sil Yoon, John R. YatesIIIIII & Marc Montminy. (2019) Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment. iScience 11, pages 134-145.
Crossref
Crossref
Yunfei Li, Yajuan Xiao, Hsuan-Pei Lin, Derek Reichel, Younsoo Bae, Eun Y. Lee, Yiguo Jiang, Xuefei Huang, Chengfeng Yang & Zhishan Wang. (2019) In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis. Biomaterials 188, pages 160-172.
Crossref
Crossref
Holly Fowle, Ziran Zhao & Xavier Graña. 2019.
55
93
.
Yang Mi, Rajendra Kumar Gurumurthy, Piotr K. Zadora, Thomas F. Meyer & Cindrilla Chumduri. (2018)
Chlamydia trachomatis
Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling
. mBio 9:6.
Crossref
Crossref
Anne Bertolotti. (2018) The split protein phosphatase system. Biochemical Journal 475:23, pages 3707-3723.
Crossref
Crossref
Haytham Mehsen, Vincent Boudreau, Damien Garrido, Mohammed Bourouh, Myreille Larouche, Paul S. Maddox, Andrew Swan & Vincent Archambault. (2018)
PP2A-B55 promotes nuclear envelope reformation after mitosis in
Drosophila
. Journal of Cell Biology 217:12, pages 4106-4123.
Crossref
Crossref
Ling Liu, Zile Huang, Jingjing Chen, Jiangang Wang & Shuying Wang. (2018) Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Crossref
Kamila Marzec & Andrew Burgess. (2018) The Oncogenic Functions of MASTL Kinase. Frontiers in Cell and Developmental Biology 6.
Crossref
Crossref
Rolf Müller, Maria Stumpf, Regina Wehrstedt, Salil K. Sukumaran, Malte A. Karow, Marija Marko, Angelika A. Noegel & Ludwig Eichinger. (2018)
The regulatory subunit phr2AB of
Dictyostelium discoideum
phosphatase PP2A interacts with the centrosomal protein CEP161, a CDK5RAP2 ortholog
. Genes to Cells 23:10, pages 923-931.
Crossref
Crossref
Sun-Wei Guo. (2018) Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis. Reproductive Medicine and Biology 17:4, pages 369-397.
Crossref
Crossref
Yanrui HuangShuang YuSiting CaoYali YinShubin HongHongyu GuanYanbing LiHaipeng Xiao. (2018) MicroRNA-222 Promotes Invasion and Metastasis of Papillary Thyroid Cancer Through Targeting Protein Phosphatase 2 Regulatory Subunit B Alpha Expression. Thyroid 28:9, pages 1162-1173.
Crossref
Crossref
Shen Tang, Fu Qin, Xinhang Wang, Ziwei Liang, Haiqing Cai, Laiming Mo, Yue Huang, Boyin Liang, Xuejing Wei, Qingqing Ao, Yilu Xu, Yuyang Liu, Deqiang Xiao, Songchao Guo, Cailing Lu & Xiyi Li. (2018)
H
2
O
2
induces PP2A demethylation to downregulate mTORC1 signaling in HEK293 cells
. Cell Biology International 42:9, pages 1182-1191.
Crossref
Crossref
Michiel Remmerie & Veerle Janssens. (2018) Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late. International Journal of Molecular Sciences 19:8, pages 2380.
Crossref
Crossref
Ji Hye Shin, Chang Wook Park, Gyesoon Yoon, Sun Mi Hong & Kwan Yong Choi. (2018) NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation. Oncogenesis 7:8.
Crossref
Crossref
Alvaro Nuno-Perez, Anna Tchenio, Manuel Mameli & Salvatore Lecca. (2018) Lateral Habenula Gone Awry in Depression: Bridging Cellular Adaptations With Therapeutics. Frontiers in Neuroscience 12.
Crossref
Crossref
Magali Trayssac, Yusuf A. Hannun & Lina M. Obeid. (2018) Role of sphingolipids in senescence: implication in aging and age-related diseases. Journal of Clinical Investigation 128:7, pages 2702-2712.
Crossref
Crossref
David L. BrautiganShirish Shenolikar. (2018) Protein Serine/Threonine Phosphatases: Keys to Unlocking Regulators and Substrates. Annual Review of Biochemistry 87:1, pages 921-964.
Crossref
Crossref
Evelien M. Bunnik, Kate B. Cook, Nelle Varoquaux, Gayani Batugedara, Jacques Prudhomme, Anthony Cort, Lirong Shi, Chiara Andolina, Leila S. Ross, Declan Brady, David A. Fidock, Francois Nosten, Rita Tewari, Photini Sinnis, Ferhat Ay, Jean-Philippe Vert, William Stafford Noble & Karine G. Le Roch. (2018) Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages. Nature Communications 9:1.
Crossref
Crossref
Barbara Baro, Soraya Játiva, Inés Calabria, Judith Vinaixa, Joan-Josep Bech-Serra, Carolina de LaTorre, João Rodrigues, María Luisa Hernáez, Concha Gil, Silvia Barceló-Batllori, Martin R Larsen & Ethel Queralt. (2018) SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast. GigaScience 7:5.
Crossref
Crossref
Daniela S. Thommen & Ton N. Schumacher. (2018) T Cell Dysfunction in Cancer. Cancer Cell 33:4, pages 547-562.
Crossref
Crossref
Krzysztof Wrzesinski & Stephen Fey. (2018) Metabolic Reprogramming and the Recovery of Physiological Functionality in 3D Cultures in Micro-Bioreactors. Bioengineering 5:1, pages 22.
Crossref
Crossref
Bob Meeusen & Veerle Janssens. (2018) Tumor suppressive protein phosphatases in human cancer: Emerging targets for therapeutic intervention and tumor stratification. The International Journal of Biochemistry & Cell Biology 96, pages 98-134.
Crossref
Crossref
Joshua Thompson & Christopher Williams. (2018) Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and Cancer. Genes 9:3, pages 121.
Crossref
Crossref
Feifei Wang, Songli Zhu, Laura A. Fisher, Weidong Wang, Gregory G. Oakley, Chunling Li & Aimin Peng. (2018) Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Scientific Reports 8:1.
Crossref
Crossref
Ziming Mao, Chunying Liu, Xuejing Lin, Bin Sun & Changqing Su. (2018) PPP2R5A: A multirole protein phosphatase subunit in regulating cancer development. Cancer Letters 414, pages 222-229.
Crossref
Crossref
Bo Liu, Li-Hua Sun, Yan-Fei Huang, Li-Jun Guo & Li-Shu Luo. (2018) Protein phosphatase 2ACα gene knock-out results in cortical atrophy through activating hippo cascade in neuronal progenitor cells. The International Journal of Biochemistry & Cell Biology 95, pages 53-62.
Crossref
Crossref
Nando Cervone, Rosa Della Monica, Angela Flavia Serpico, Cinzia Vetrei, Mario Scaraglio, Roberta Visconti & Domenico Grieco. (2017) Evidence that PP2A activity is dispensable for spindle assembly checkpoint-dependent control of Cdk1. Oncotarget 9:7, pages 7312-7321.
Crossref
Crossref
Kristoffer Unterbruner, Frank Matthes, Judith Schilling, Rohit Nalavade, Stephanie Weber, Jennifer Winter & Sybille Krauß. (2018) MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression. PLOS ONE 13:1, pages e0190437.
Crossref
Crossref
Veerle Janssens. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules
4893
4902
.
Edward Alain B. Pajarillo, Sang Hoon Kim, Valerie Diane Valeriano, Ji Yoon Lee & Dae-Kyung Kang. (2017) Proteomic View of the Crosstalk between Lactobacillus mucosae and Intestinal Epithelial Cells in Co-culture Revealed by Q Exactive-Based Quantitative Proteomics. Frontiers in Microbiology 8.
Crossref
Crossref
Displaying 200 of 212 citing articles. Use the download link below to view the full list of citing articles.
Download full citations list