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Leukemia & Lymphoma Volume 40, 2000 - Issue 1-2
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Original Article

Telomere Dynamics and Genetic Instability in Disease Progression of Chronic Myeloid Leukemia

Kazuma Ohyashiki First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, JapanCorrespondence[email protected]
,
Hiroshi Iwama First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
,
Tetsuzo Tauchi First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
,
Takashi Shimamoto First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
,
Shigefumi Hayashi First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
,
Keiko Ando First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
,
Ken Kawakubo First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
&
Junko H. Ohyashiki1 First Department of Internal Medicine, Tokyo Medical University, Tokyo, 160-0023, Japan
 show all
Pages 49-56 | Received 10 Mar 2000, Published online: 01 Jul 2009

Citations (23)

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Stephan M. Feller, Gabriele Tuchscherer & Jan Voss. (2003) High Affinity Molecules Disrupting GRB2 Protein Complexes as a Therapeutic Strategy for Chronic Myelogenous Leukaemia. Leukemia & Lymphoma 44:3, pages 411-427.
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Kazuma Ohyashiki, Hiroshi Iwama, Naoyuki Yahata, Tetsuzou Tauchi, Ken Kawakubo, Takashi Shimamoto & Junko H. Ohyashiki. (2001) Telomere Dynamics in Myelodysplastic Syndromes and Acute Leukemic Transformation. Leukemia & Lymphoma 42:3, pages 291-299.
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Articles from other publishers (21)

Erfan Zaker, Negar Nouri, Sepehr Sorkhizadeh, Hamidreza Ghasemirad, Amir Hossein Hajijafari & Fateme Zare. (2023) The importance of personalized medicine in chronic myeloid leukemia management: a narrative review. Egyptian Journal of Medical Human Genetics 24:1.
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Bilal Abdulmawjood, Beatriz Costa, Catarina Roma-Rodrigues, Pedro V. Baptista & Alexandra R. Fernandes. (2021) Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?. International Journal of Molecular Sciences 22:22, pages 12516.
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Anna Deregowska, Monika Pepek, Katarzyna Pruszczyk, Marcin M. Machnicki, Maciej Wnuk & Tomasz Stoklosa. (2020) Differential Regulation of Telomeric Complex by BCR-ABL1 Kinase in Human Cellular Models of Chronic Myeloid Leukemia—From Single Cell Analysis to Next-Generation Sequencing. Genes 11:10, pages 1145.
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Anne-Sophie BouillonMonica S. Ventura FerreiraShady Adnan AwadJohan RichterAndreas HochhausVolker KunzmannJolanta DenglerJeroen JanssenGert OssenkoppelePeter E. WesterweelPeter A. W. te BoekhorstFrancois-Xavier MahonHenrik Hjorth-HansenSusanne IsfortThoas Fioretos, Sebastian HummelMirle SchemionekStefan WilopSteffen KoschmiederSusanne Saußele, Satu MustjokiFabian BeierTim H. Brümmendorf. (2018) Telomere shortening correlates with leukemic stem cell burden at diagnosis of chronic myeloid leukemia. Blood Advances 2:13, pages 1572-1579.
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Cagatay Gunes, Alush Irene Avila & K. Lenhard Rudolph. (2018) Telomeres in cancer. Differentiation 99, pages 41-50.
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Ali Amini, Seyed Hamidollah Ghaffari, Yousef Mortazai, Karim Daliri, Shahrouz Taranejoo, Kamran Alimoghadam & Ardeshir Ghavamzadeh. (2014) Expression pattern of hTERT telomerase subunit gene in different stages of chronic myeloid leukemia. Molecular Biology Reports 41:9, pages 5557-5561.
Crossref
Oumar Samassekou. (2013) Dynamic Length Changes of Telomeres and Their Nuclear Organization in Chronic Myeloid Leukemia. Cancers 5:4, pages 1086-1102.
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Marco Ruella, Silvia Salmoiraghi, Alessandra Risso, Alessandra Carobbio, Stefano Buttiglieri, Tiziana Spatola, Piera Sivera, Irene Ricca, Tiziano Barbui, Corrado Tarella & Alessandro Rambaldi. (2013) Telomere shortening in Ph-negative chronic myeloproliferative neoplasms: A biological marker of polycythemia vera and myelofibrosis, regardless of hydroxycarbamide therapy. Experimental Hematology 41:7, pages 627-634.
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Shahinaz M. Gadalla & Sharon A. Savage. (2011) Telomere biology in hematopoiesis and stem cell transplantation. Blood Reviews 25:6, pages 261-269.
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Rie Sano, Tamiko Nakajima, Keiko Takahashi, Rieko Kubo, Shin Yazawa & Yoshihiko Kominato. (2011) The 3′ flanking region of the human ABO histo-blood group gene is involved in negative regulation of gene expression. Legal Medicine 13:1, pages 22-29.
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Gunhild Keller, Ute Brassat, Melanie Braig, Denise Heim, Henning Wege & Tim H. Brümmendorf. (2009) Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy. Hematological Oncology 27:3, pages 123-129.
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Murielle Mimeault & Surinder K. Batra. (2009) Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications. Ageing Research Reviews 8:2, pages 94-112.
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H. Ohyashiki Junko & Ohyashiki Kazuma. 2009. Telomeres and Telomerase in Cancer. Telomeres and Telomerase in Cancer 211 224 .
Ulrike Hartmann, Stefan Balabanov, Patrick Ziegler, Jörg Fellenberg, Heiko van der Kuip, Justus Duyster, Hans-Peter Lipp, Carsten Bokemeyer, Lothar Kanz & Tim H. Brümmendorf. (2005) Telomere length and telomerase activity in the BCR-ABL-transformed murine Pro-B cell line BaF3 is unaffected by treatment with imatinib. Experimental Hematology 33:5, pages 542-549.
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Ande Satyanarayana & K. Lenhard Rudolph. 2005. Signaling Pathways in Liver Diseases. Signaling Pathways in Liver Diseases 333 339 .
Ngaire J. Elwood. (2017) Telomere Biology of Human Hematopoietic Stem Cells. Cancer Control 11:2, pages 77-85.
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Ulrike Hartmann, Fabian Beier & Tim H. Brümmendorf. (2004) Telomere length analysis by fluorescence in situ hybridization and flow cytometry (Flow-FISH)/Telomerlängen-Messung mittels Fluoreszenz-in-situ-Hybridisierung und Durchflusszytometrie (Flow-FISH). LaboratoriumsMedizin 28:4, pages 307-316.
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N von Bubnoff, C Peschel & J Duyster. (2003) Resistance of Philadelphia-chromosome positive leukemia towards the kinase inhibitor imatinib (STI571, Glivec): a targeted oncoprotein strikes back. Leukemia 17:5, pages 829-838.
Crossref
Srdan Verstovsek, Hagop Kantarjian, Taghi Manshouri, Jorge Cortes, Stefan Faderl, Francis J. Giles, Michael Keating & Maher Albitar. (2003) Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia. Cancer 97:5, pages 1248-1252.
Crossref
Duncan L. Smith, Caroline A. Evans, Andrew Pierce, Simon J. Gaskell & Anthony D. Whetton. (2002) Changes in the Proteome Associated with the Action of Bcr-Abl Tyrosine Kinase Are Not Related to Transcriptional Regulation. Molecular & Cellular Proteomics 1:11, pages 876-884.
Crossref
MV Blagosklonny. (2002) STI-571 must select for drug-resistant cells but ‘no cell breathes fire out of its nostrils like a dragon’. Leukemia 16:4, pages 570-572.
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