636
Views
58
CrossRef citations to date
0
Altmetric
Research Article

Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells

, , , , , , , , , & show all
Pages 315-322 | Received 19 Apr 2011, Accepted 18 Aug 2011, Published online: 15 Nov 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Shaoyang Zhang, Xiufeng Liu, Saleh Abdulmomen Ali Mohammed, Hui Li, Wanhua Cai, Wen Guan, Daiyun Liu, Yanli Wei, Dade Rong, Ying Fang, Farhan Haider, Haimei Lv, Ziwei Jin, Xiaomin Chen, Zhuomao Mo, Lujie Li, Shulan Yang & Haihe Wang. (2022) Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers. Autophagy 18:8, pages 1822-1840.
Read now
Liangchun Yang, Fanghua Ye, Li Zeng, Yanling Li & Wenwen Chai. (2020) Knockdown of HMGB1 Suppresses Hypoxia-Induced Mitochondrial Biogenesis in Pancreatic Cancer Cells. OncoTargets and Therapy 13, pages 1187-1198.
Read now
Tianwei Xu, Lihua Jiang & Zhaoxia Wang. (2019) The progression of HMGB1-induced autophagy in cancer biology. OncoTargets and Therapy 12, pages 365-377.
Read now
Qiwen Wang, Bingyu Ye, Ping Wang, Fenjie Yao, Chunyan Zhang & Guoying Yu. (2019) Overview of microRNA-199a Regulation in Cancer. Cancer Management and Research 11, pages 10327-10335.
Read now
Xiaofang Sun & Daolin Tang. (2014) HMGB1-dependent and -independent autophagy. Autophagy 10:10, pages 1873-1876.
Read now
Ke Liu, Jun Huang, Min Xie, Yan Yu, Shan Zhu, Rui Kang, Lizhi Cao, Daolin Tang & Xuanchu Duan. (2014) MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell. Autophagy 10:3, pages 442-452.
Read now

Articles from other publishers (52)

Young Yun Jung, Kwang Seok Ahn & Mingzhi Shen. (2024) Unveiling autophagy complexity in leukemia: The molecular landscape and possible interactions with apoptosis and ferroptosis. Cancer Letters 582, pages 216518.
Crossref
Li-Hua Shao, Li Zhu, Meng Wang, Yue Ning, Feng-Qin Chen, Xia-Qing Gao, Chun-Ting Yang, Hong-Wei Wang & Hai-Long Li. (2023) Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review). International Journal of Molecular Medicine 52:2.
Crossref
Tianxin Lyu, Xudong Li & Yongping Song. (2023) Ferroptosis in acute leukemia. Chinese Medical Journal 136:8, pages 886-898.
Crossref
Hamed Bashiri & Hossein Tabatabaeian. (2023) Autophagy: A Potential Therapeutic Target to Tackle Drug Resistance in Multiple Myeloma. International Journal of Molecular Sciences 24:7, pages 6019.
Crossref
旭升 王. (2023) Drug Resistance Mechanism of Tri-ple-Negative Breast Cancer and Research Progress with DLG5. Advances in Clinical Medicine 13:11, pages 18067-18076.
Crossref
Fatemeh Zahedipour, Prashant Kesharwani & Amirhossein Sahebkar. 2023. Aptamers Engineered Nanocarriers for Cancer Therapy. Aptamers Engineered Nanocarriers for Cancer Therapy 51 83 .
Simona Pompili, Antonella Vetuschi, Roberta Sferra & Alfredo Cappariello. (2022) Extracellular Vesicles and Resistance to Anticancer Drugs: A Tumor Skeleton Key for Unhinging Chemotherapies. Frontiers in Oncology 12.
Crossref
Weixin Lai, Xinyu Li, Qian Kong, Han Chen, Yunyao Li, Lu-Hong Xu & Jianpei Fang. (2021) Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells. Cancer Cell International 21:1.
Crossref
María Julia Lamberti, Annunziata Nigro, Vincenzo Casolaro, Natalia Belén Rumie Vittar & Jessica Dal Col. (2021) Damage-Associated Molecular Patterns Modulation by microRNA: Relevance on Immunogenic Cell Death and Cancer Treatment Outcome. Cancers 13:11, pages 2566.
Crossref
Chit Tam, Shitao Rao, Mary Miu Yee Waye, Tzi Bun Ng & Chi Chiu Wang. (2021) Autophagy signals orchestrate chemoresistance of gynecological cancers. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:2, pages 188525.
Crossref
Bo Li, Xin Peng, He Li, Fei Chen, Yuxia Chen, Yingqian Zhang & Kai Le. (2020) The performance of the alarmin HMGB1 in pediatric diseases: From lab to clinic. Immunity, Inflammation and Disease 9:1, pages 8-30.
Crossref
Lin Run, Liping Wang, Xiting Nong, Nan Li, Xin Huang & Yang Xiao. (2020) Involvement of HMGB1 in vemurafenib resistance in thyroid cancer cells harboring BRAF (V600E) mutation by regulating excessive autophagy. Endocrine 71:2, pages 418-426.
Crossref
Xuening Pang, Xiaoyi Zhang, Yuhuan Jiang, Quanzhong Su, Qun Li & Zichao Li. (2021) Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in Cancer. Biomolecules 11:2, pages 135.
Crossref
Lulu Liu, Jingjing Zhang, Xianning Zhang, Panpan Cheng, Lei Liu, Qian Huang, Haihui Liu, Saisai Ren, Peng Wei, Cuiling Wang, Cuiyun Dou, Lulu Chen, Xin Liu, Hao Zhang & Mingtai Chen. (2020) HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target. Journal of Molecular Medicine 99:1, pages 107-118.
Crossref
Shunling Yuan, Zhaoping Liu, Zhenru Xu, Jing Liu & Ji Zhang. (2020) High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignancies. Journal of Hematology & Oncology 13:1.
Crossref
Wenwen Chai, Fanghua Ye, Li Zeng, Yanling Li & Liangchun Yang. (2019) HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt & Kedar S. Prabhavalkar. (2019) High Mobility Group Box-1 (HMGB1): A Potential Target in Therapeutics. Current Drug Targets 20:14, pages 1474-1485.
Crossref
Singh, Cho, Kim, Baek, Lee & Kang. (2019) Morin Hydrate Reverses Cisplatin Resistance by Impairing PARP1/HMGB1-Dependent Autophagy in Hepatocellular Carcinoma. Cancers 11:7, pages 986.
Crossref
Suresh Singh Yadav, Manoj Kumar, Akhil Varshney & Pramod Kumar Yadava. (2019) KLF4 sensitizes the colon cancer cell HCT-15 to cisplatin by altering the expression of HMGB1 and hTERT. Life Sciences 220, pages 169-176.
Crossref
Hendrik Folkerts, Susan Hilgendorf, Edo Vellenga, Edwin Bremer & Valerie R. Wiersma. (2018) The multifaceted role of autophagy in cancer and the microenvironment. Medicinal Research Reviews 39:2, pages 517-560.
Crossref
Sae Won Kim, Han Wook Park, Hyekang Kim, Seungwon Lee, So Young Choi, Yunji Park & Seung-Woo Lee. (2019) Evaluating Antitumor Activity of Kiatomab by Targeting Cancer Stem Cell-Specific KIAA1114 Antigen in Mice. Immune Network 19:6.
Crossref
Beibei Liu, Xiaowei Qi, Xiufen Zhang, Danfeng Gao, Kai Fang, Zijian Guo & Lihua Li. (2018) Med19 is involved in chemoresistance by mediating autophagy through HMGB1 in breast cancer. Journal of Cellular Biochemistry 120:1, pages 507-518.
Crossref
Xing Guo, Donghua He, Enfan Zhang, Jing Chen, Qingxiao Chen, Yi Li, Li Yang, Yang Yang, Yi Zhao, Gang Wang, Jingsong He & Zhen Cai. (2018) HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Huijuan Jiang, Xigang Hu, Hongzhi Zhang & Wenbo Li. (2017) Down-regulation of LncRNA TUG1 enhances radiosensitivity in bladder cancer via suppressing HMGB1 expression. Radiation Oncology 12:1.
Crossref
Hubin Yin, Xiaoyu Yang, Wen Gu, Yan Liu, Xinyuan Li, Xiaolong Huang, Xin Zhu, Yong Tao, Xin Gou & Weiyang He. (2017) HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation. Oncotarget 8:42, pages 71642-71656.
Crossref
Hua-Chuan Zheng. (2017) The molecular mechanisms of chemoresistance in cancers. Oncotarget 8:35, pages 59950-59964.
Crossref
Eleonora Foglio, Giovanni Puddighinu, Antonia Germani, Matteo A. Russo & Federica Limana. (2017) HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition. Journal of Cellular Physiology 232:5, pages 1135-1143.
Crossref
TianJun ChenHui RenAsmitanand ThakurTian YangYang LiShuo ZhangTing WangMingWei Chen. (2016) Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy. DNA and Cell Biology 35:12, pages 751-757.
Crossref
Yongsong Cai, Peng Xu, Le Yang, Ke Xu, Jialin Zhu, Xiaoqing Wu, Congshan Jiang, Qiling Yuan, Bo Wang, Yuanbo Li & Yusheng Qiu. (2016) HMGB1-mediated autophagy decreases sensitivity to oxymatrine in SW982 human synovial sarcoma cells. Scientific Reports 6:1.
Crossref
Zhaoxia Zhang, Benqing Wu, Wenwen Chai, Lizhi Cao, Yangping Wang, Yan Yu & Liangchun Yang. (2016) Knockdown of WAVE1 enhances apoptosis of leukemia cells by downregulating autophagy. International Journal of Oncology.
Crossref
Jun Huang, Ke Liu, Deye Song, Muliang Ding, Junjie Wang, Qingping Jin & Jiangdong Ni. (2016) Krüppel‐like factor 4 promotes high‐mobility group box 1‐induced chemotherapy resistance in osteosarcoma cells. Cancer Science 107:3, pages 242-249.
Crossref
Rui Kang & Daolin Tang. 2016. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging 173 185 .
Gaëlle Savreux-Lenglet, Sabine Depauw & Marie-Hélène David-Cordonnier. (2015) Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts. International Journal of Molecular Sciences 16:11, pages 26555-26581.
Crossref
Yirong Xu, Zhenwen Chen, Guangheng Zhang, Yanfeng Xi, Ruifang Sun, Fei Chai, Xiaogang Wang, Jianhong Guo & Lin Tian. (2015) HMGB1 overexpression correlates with poor prognosis in early-stage squamous cervical cancer. Tumor Biology 36:11, pages 9039-9047.
Crossref
QIAN KONG, LU-HONG XU, WEI XU, JIAN-PEI FANG & HONG-GUI XU. (2015) HMGB1 translocation is involved in the transformation of autophagy complexes and promotes chemoresistance in leukaemia. International Journal of Oncology 47:1, pages 161-170.
Crossref
Naoki Takezako, Naohiro Sekiguchi, Akihisa Nagata, Chiho Homma, Yayoi Takezako, Satoshi Noto, Kazuhiko Natori & Akiyoshi Miwa. (2015) Recombinant human thrombomodulin in the treatment of acute myeloid leukemia patients complicated by disseminated intravascular coagulation: retrospective analysis of outcomes between patients treated with heparin and recombinant human thrombomodulin therapy. Thrombosis Research 136:1, pages 20-23.
Crossref
Banzhou Pan, Dongqin Chen, Jiayuan Huang, Rui Wang, Bing Feng, Haizhu Song & Longbang Chen. (2014) HMGB1-mediated autophagy promotes docetaxel resistance in human lung adenocarcinoma. Molecular Cancer 13:1.
Crossref
Rui Kang, Ruochan Chen, Qiuhong Zhang, Wen Hou, Sha Wu, Lizhi Cao, Jin Huang, Yan Yu, Xue-gong Fan, Zhengwen Yan, Xiaofang Sun, Haichao Wang, Qingde Wang, Allan Tsung, Timothy R. Billiar, Herbert J. ZehIIIIII, Michael T. Lotze & Daolin Tang. (2014) HMGB1 in health and disease. Molecular Aspects of Medicine 40, pages 1-116.
Crossref
Valeria Chirico, Antonio Lacquaniti, Vincenzo Salpietro, Caterina Munafò, Maria Pia Calabrò, Michele Buemi, Teresa Arrigo & Carmelo Salpietro. (2014) High-mobility group box 1 (HMGB1) in childhood: from bench to bedside. European Journal of Pediatrics 173:9, pages 1123-1136.
Crossref
Jin-Shui Zhu. (2014) Knockdown of HMGB1 inhibits growth and invasion of gastric cancer cells through the NF-κB pathway in vitro and in vivo. International Journal of Oncology.
Crossref
Daolin Tang, Rui Kang, Bennett Van Houten, Herbert J. Zeh, Timothy R. Billiar & Michael T. Lotze. (2014) High Mobility Group Box 1 (HMGB1) Phenotypic Role Revealed with Stress. Molecular Medicine 20:1, pages 359-362.
Crossref
Mohammad Soltany-Rezaee-Rad, Negar Mottaghi-Dastjerdi, Neda Setayesh, Gholamreza Roshandel, Farzaneh Ebrahimifard & Zargham Sepehrizadeh. (2014) Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with Autophagy. Gastroenterology Research and Practice 2014, pages 1-8.
Crossref
Chung-Hyun Park, Byung-Hoon Lee, Sang-Gun Ahn, Jung-Hoon Yoon & Seon-Hee Oh. (2013) Serine 9 and Tyrosine 216 Phosphorylation of GSK-3β Differentially Regulates Autophagy in Acquired Cadmium Resistance. Toxicological Sciences 135:2, pages 380-389.
Crossref
Fu-ping Wang, Lei Li, Jing Li, Ji-yao Wang, Ling-yan Wang & Wei Jiang. (2013) High Mobility Group Box-1 Promotes the Proliferation and Migration of Hepatic Stellate Cells via TLR4-Dependent Signal Pathways of PI3K/Akt and JNK. PLoS ONE 8:5, pages e64373.
Crossref
Gaëlle Lenglet, Sabine Depauw, Denise Mendy & Marie-Hélène David-Cordonnier. (2013) Protein recognition of the S23906-1–DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Biochemical Journal 452:1, pages 147-159.
Crossref
Yan Yu. (2013) Hsp27: A novel therapeutic target for pediatric M4/M5 acute myeloid leukemia. Oncology Reports.
Crossref
Man Sup KwakJeon-Soo Shin. (2013) Current Understanding of HMGB1-mediated Autophagy. Journal of Bacteriology and Virology 43:2, pages 148.
Crossref
Jie Chen, Xiaoyan Liu, Jie Zhang & Yueran Zhao. (2012) Targeting HMGB1 inhibits ovarian cancer growth and metastasis by lentivirus-mediated RNA interference. Journal of Cellular Physiology 227:11, pages 3629-3638.
Crossref
Bethsebah Gekonge, Andrea D Raymond, Xiangfan Yin, Jay Kostman, Karam Mounzer, Ronald G Collman, Louise Showe & Luis J Montaner. (2012) Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study. Journal of Leukocyte Biology 92:2, pages 397-405.
Crossref
Jie Chen, Bo Xi, Yueran Zhao, Yang Yu, Jie Zhang & Chunyu Wang. (2012) RETRACTED: High-mobility group protein B1 (HMGB1) is a novel biomarker for human ovarian cancer. Gynecologic Oncology 126:1, pages 109-117.
Crossref
Ning Xu, Jianjun Zhang, Conghuan Shen, Yi Luo, Lei Xia, Feng Xue & Qiang Xia. (2012) Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. Biochemical and Biophysical Research Communications 423:4, pages 826-831.
Crossref
Sunandini Sridhar, Yair Botbol, Fernando Macian & Ana Maria Cuervo. (2012) Autophagy and disease: always two sides to a problem. The Journal of Pathology 226:2, pages 255-273.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.