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Research Article

Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia

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Pages 1769-1778 | Received 02 Nov 2011, Accepted 29 Jan 2012, Published online: 13 Mar 2012

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Azam Shamsian, Mohammad Reza Sepand, Marziye Javaheri Kachousangi, Tahereh Dara, Seyed Nasser Ostad, Fatemeh Atyabi & Mohammad Hossein Ghahremani. (2020) Targeting Tumorigenicity of Breast Cancer Stem Cells Using SAHA/Wnt-b Catenin Antagonist Loaded Onto Protein Corona of Gold Nanoparticles. International Journal of Nanomedicine 15, pages 4063-4078.
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Yun Deng, Qian Cheng & Jing He. (2023) HDAC inhibitors: Promising agents for leukemia treatment. Biochemical and Biophysical Research Communications 680, pages 61-72.
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Kishor Pant, Senthil K. Venugopal, Maria J. Lorenzo Pisarello & Sergio A. Gradilone. (2023) The Role of Gut Microbiome-Derived Short-Chain Fatty Acid Butyrate in Hepatobiliary Diseases. The American Journal of Pathology 193:10, pages 1455-1467.
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Hongjuan You, Qi Li, Delong Kong, Xiangye Liu, Fanyun Kong, Kuiyang Zheng & Renxian Tang. (2022) The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation. Cellular & Molecular Biology Letters 27:1.
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Soo Jin Kim, Suntae Kim, Yong June Choi, U Ji Kim & Keon Wook Kang. (2022) CKD-581 Downregulates Wnt/β-Catenin Pathway by DACT3 Induction in Hematologic Malignancy. Biomolecules & Therapeutics 30:5, pages 435-446.
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Cristina Trejo-Solis, Angel Escamilla-Ramirez, Dolores Jimenez-Farfan, Rosa Angelica Castillo-Rodriguez, Athenea Flores-Najera & Arturo Cruz-Salgado. (2021) Crosstalk of the Wnt/β-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells. Pharmaceuticals 14:9, pages 871.
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O. O. Gnedina & M. V. Igotti. (2021) Effect of Sodium Butyrate on Proliferative Signaling Cascades in Sensitive and Resistant to Histone Deacetylase Inhibitors Cells. Cell and Tissue Biology 15:3, pages 236-247.
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Somayeh Hashemi-Sheikhshabani, Zeinab Amini-Farsani, Mehdi Shamsara, Zahra Sajadpoor, Mohammad Hossein Sangtarash & Hossein Teimori. (2019) Effect of valproic acid on cisplatin-resistant ovarian cancer cell lines. Journal of Shahrekord University of Medical Sciences 21:1, pages 39-44.
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Gabriele Riva, Chiara Cilibrasi, Riccardo Bazzoni, Massimiliano Cadamuro, Caterina Negroni, Valentina Butta, Mario Strazzabosco, Leda Dalprà, Marialuisa Lavitrano & Angela Bentivegna. (2018) Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation. Genes 9:11, pages 522.
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Xiaoming Lyu, Jinbang Li, Xi Yun, Rui Huang, Xubin Deng, Yingping Wang, Youming Chen & Gang Xiao. (2017) miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia. Oncology Reports 37:3, pages 1469-1476.
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Leila Haery, Ryan C. Thompson & Thomas D. Gilmore. (2015) Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy. Genes & Cancer 6:5-6, pages 184-213.
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Sofie Peirs, Joni Van der Meulen, Inge Van de Walle, Tom Taghon, Frank Speleman, Bruce Poppe & Pieter Van Vlierberghe. (2015) Epigenetics in T-cell acute lymphoblastic leukemia. Immunological Reviews 263:1, pages 50-67.
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Qing-Qiang Shi, Guo-Wei Zuo, Zi-Qiang Feng, Lv-Cui Zhao, Lian Luo, Zhi-Mei You, Dang-Yang Li, Jing Xia, Jing Li & Di-Long Chen. (2014) Effect of Trichostatin A on Anti HepG2 Liver Carcinoma Cells: Inhibition of HDAC Activity and Activation of Wnt/β-Catenin Signaling. Asian Pacific Journal of Cancer Prevention 15:18, pages 7849-7855.
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Machteld M Tiemessen & Frank JT Staal. (2013) Wnt signaling in leukemias and myeloma: T-cell factors are in control. Future Oncology 9:11, pages 1757-1772.
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M. L. Barreiro Arcos, H. A. Sterle, C. Vercelli, E. Valli, M. F. Cayrol, A. J. Klecha, M. A. Paulazo, M. C. Diaz Flaqué, A. M. Franchi & G. A. Cremaschi. (2013) Induction of apoptosis in T lymphoma cells by long-term treatment with thyroxine involves PKCζ nitration by nitric oxide synthase. Apoptosis 18:11, pages 1376-1390.
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