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Journal of Drug Targeting Volume 21, 2013 - Issue 5
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Research Article

The receptor binding fragment of alpha-fetoprotein is a promising new vector for the selective delivery of antineoplastic agents

Galina A. PosypanovaNBIC Centre, National Research Centre “Kurchatov Institute” MoscowRussian FederationCorrespondence[email protected]
,
Vladimir A. MakarovNBIC Centre, National Research Centre “Kurchatov Institute” MoscowRussian Federation
,
Mariya V. SavvateevaEngelhardt Institute of Molecular Biology Russian Academy of Sciences MoscowRussian Federation
,
Anastasiya V. BereznikovaDepartment of Biology, Moscow State University MoscowRussian Federation
&
Evgeny S. SeverinDepartment of Biology, Moscow State University MoscowRussian Federation
Pages 458-465 | Received 03 Oct 2012, Accepted 08 Jan 2013, Published online: 19 Apr 2013

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G. J. Mizejewski. (2015) The alpha-fetoprotein third domain receptor binding fragment: in search of scavenger and associated receptor targets. Journal of Drug Targeting 23:6, pages 538-551.
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Articles from other publishers (7)

Xiaobing Chen, Zijuan Zou, Wei Li, Xu Dong, Yi Chen, Yan Lu, Mingyue Zhu, Mengsen Li & Bo Lin. (2024) α-Conotoxin recombinant protein ImI-AFP3 efficiently inhibits the growth and migration of lung cancer cells. Protein Expression and Purification 215, pages 106405.
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Qiujiao Wang, Wei Li, Minni Zhang, Zijuan Zou, Xu Dong, Yi Chen, Junnv Xu, Mingyue Zhu, Mengsen Li & Bo Lin. (2022) α‐Fetoprotein fragment synergizes with sorafenib to inhibit hepatoma cell growth and migration and promote the apoptosis. Journal of Cellular and Molecular Medicine 26:21, pages 5426-5438.
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Mariya B Sokol, Nikita G Yabbarov, Mariia R Mollaeva, Margarita V Chirkina, Murad D Mollaev, Artur I Zabolotsky, Sergey L Kuznetsov & Elena D Nikolskaya. (2022) Alpha-fetoprotein mediated targeting of polymeric nanoparticles to treat solid tumors. Nanomedicine 17:18, pages 1217-1235.
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Bo Lin, Xu Dong, Qiujiao Wang, Wei Li, Mingyue Zhu & Mengsen Li. (2021) AFP-Inhibiting Fragments for Drug Delivery: The Promise and Challenges of Targeting Therapeutics to Cancers. Frontiers in Cell and Developmental Biology 9.
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M. Mollaev, N. Gorokhovets, E. Nikolskaya, M. Faustova, A. Zabolotsky, O. Zhunina, M. Sokol, I. Zamulaeva, E. Severin & N. Yabbarov. (2019) Type of pH sensitive linker reveals different time-dependent intracellular localization, in vitro and in vivo efficiency in alpha-fetoprotein receptor targeted doxorubicin conjugate. International Journal of Pharmaceutics 559, pages 138-146.
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G. J. Mizejewski. (2016) The alpha-fetoprotein (AFP) third domain: a search for AFP interaction sites of cell cycle proteins. Tumor Biology 37:9, pages 12697-12711.
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Fan Yang, Weilun Ai, Fagang Jiang, Xin Liu, Zebo Huang & Shibin Ai. (2016) Preclinical Evaluation of an Epidermal Growth Factor Receptor–Targeted Doxorubicin–Peptide Conjugate: Toxicity, Biodistribution, and Efficacy in Mice. Journal of Pharmaceutical Sciences 105:2, pages 639-649.
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