The receptor binding fragment of alpha-fetoprotein is a promising new vector for the selective delivery of antineoplastic agents

References

• Laderoute M, Willans D, Wegmann T, Longenecker M. The identification, isolation and characterization of a 67 kilodalton, PNA-reactive autoantigen commonly expressed in human adenocarcinomas. Anticancer Res 1994;14:1233–45
   PubMed Web of Science ®Google Scholar
• Moro R, Heuguerot C, Vercelli-Retta J, et al. The use of radioiodinated alpha-fetoprotein for the scintigraphic detection of mouse mammary carcinomas. Nucl Med Commun 1984;5:5–12
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Review of the putative cell-surface receptors for alpha-fetoprotein: identification of a candidate receptor protein family. Tumor Biol 2011;32:241–58
   PubMed Web of Science ®Google Scholar
• Moro R, Tamaoki T, Wegmann TG, et al. Monoclonal antibodies directed against a widespread oncofetal antigen: the alpha-fetoprotein receptor. Tumour Biol 1993;14:116–30
   PubMed Web of Science ®Google Scholar
• Nitsvetov МB, Moskaleva ЕY, Posypanova GA, et al. Immunohistochemical study of AFP receptor expression in normal and malignant tumor human tissues. Immunologiya (Rus.) 2005;26:122–5
   Google Scholar
• Kanevsky V, Pozdnyakova LP, Aksenova OA, et al. Isolation and characterization of AFP-binding proteins from tumor and fetal human tissues. Biochem Mol Biol Int 1997;41:1143–51
   PubMedGoogle Scholar
• Severin SE, Kulakov VN, Moskaleva E, et al. The distribution of iodine-125 labeled alpha-fetoprotein in the animal organism and its accumulation in the tumor. Vestn Ross Akad Med Nauk 2012;4:11–15
   PubMedGoogle Scholar
• Uriel J, Villacampa MJ, Moro R, et al. Uptake of radiolabeled alpha-fetoprotein by mouse mammary carcinomas and its usefulness in tumor scintigraphy. Cancer Res 1984;44:5314–19
   PubMed Web of Science ®Google Scholar
• Line BR, Feustel PJ, Festin SM, et al. Scintigraphic detection of breast cancer xenografts with Tc-99m natural and recombinant human alpha-fetoprotein. Cancer Biother Radiopharm 1999;14:485–94
   PubMed Web of Science ®Google Scholar
• Crandall BF. Alpha-fetoprotein: a review. Crit Rev Clin Lab Sci 1981;15:127–85
   PubMed Web of Science ®Google Scholar
• Moskaleva EY, Posypanova GA, Koromyslova IA, et al. In vivo antitumor activity of cytotoxic drugs conjugated with human alpha-fetoprotein. Tumor Targeting 1996;2:299–306
   Google Scholar
• Severin SE, Posypanova GA, Katukov VY, et al. Antitumor activity of conjugates of the oncofetal protein alpha-fetoprotein and phthalocyanines in vitro. Biochem Mol Biol Int 1997;43:1081–9
   PubMedGoogle Scholar
• Villacampa MJ, Moro R, Naval J, et al. Alpha-fetoprotein receptors in a human breast cancer cell line. Biochem Biophys Res Commun 1984;122:1322–7
   PubMed Web of Science ®Google Scholar
• Geuskens M, Torres JM, Esteban C, Uriel J. Morphological characterization of the pathway of endocytosis and intracellular processing of transferrin and alpha-fetoprotein in human T lymphocytes stimulated with phytohemagglutinin (PHA). Eur J Cell Biol 1989;50:418–27
   PubMed Web of Science ®Google Scholar
• Alava MA, Iturralde M, Lampreave F, Pineiro A. Specific uptake of alpha-fetoprotein and albumin by rat Morris 7777 hepatoma cells. Tumour Biol 1999;20:52–64
   PubMed Web of Science ®Google Scholar
• Deutsch HF. Chemistry and biology of alpha-fetoprotein. Adv Cancer Res 1991;56:253–312
   PubMed Web of Science ®Google Scholar
• Posypanova GA, Gorokhovets NV, Makarov VA, et al. Recombinant alpha-fetoprotein C-terminal fragment: the new recombinant vector for targeted delivery. J Drug Target 2008;16:321–8
   PubMed Web of Science ®Google Scholar
• Sharapova OA, Pozdnykova NV, Laurinavichyute DK, et al. High-efficient expression, refolding and purification of functional recombinant C-terminal fragment of human alpha-fetoprotein. Protein Expr Purif 2010;73:31–5
   PubMed Web of Science ®Google Scholar
• Bremner KH, Seymour LW, Logan A, Read ML. Factors influencing the ability of nuclear localization sequence peptides to enhance nonviral gene delivery. Bioconj Chem 2003;15:152–61
   Web of Science ®Google Scholar
• Collas P, Alestrom P. Nuclear localization signals: a driving force for nuclear transport of plasmid DNA in zebrafish. Biochem Cell Biol 1997;75:633–40
   PubMed Web of Science ®Google Scholar
• Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl 1968;97:77–89
   PubMedGoogle Scholar
• Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 1986;89:271–7
   PubMed Web of Science ®Google Scholar
• Greenfield RS, Kaneko T, Daues A, et al. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker. Cancer Res 1990;50:6600–7
   PubMed Web of Science ®Google Scholar
• Braslawsky GR, Kadow K, Knipe J, et al. Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity. Cancer Immunol Immunother 1991;33:367–74
   PubMed Web of Science ®Google Scholar
• Kratz F, Beyer U, Collery P, et al. Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin. Biol Pharm Bull 1998;21:56–61
   PubMed Web of Science ®Google Scholar
• Kratz F, Beyer U, Roth T, et al. Transferrin conjugates of doxorubicin: synthesis, characterization, cellular uptake, and in vitro efficacy. J Pharm Sci 1998;87:338–46
   PubMed Web of Science ®Google Scholar
• DiMarco A. Adriamycin (NSC-123I27): mode and mechanism of action. Cancer Chemother Rep 1975;6:91–106
   Google Scholar