583
Views
40
CrossRef citations to date
0
Altmetric
Review Article

Strategies on the nuclear-targeted delivery of genes

, , &
Pages 926-939 | Received 27 Jun 2013, Accepted 27 Jul 2013, Published online: 22 Aug 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Elena Alexander. (2021) Yeasts in nanotechnology-enabled oral vaccine and gene delivery. Bioengineered 12:1, pages 8325-8335.
Read now
Bruna dos Santos Rodrigues, Sushant Lakkadwala, Takahisa Kanekiyo & Jagdish Singh. (2019) Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties. International Journal of Nanomedicine 14, pages 6497-6517.
Read now
Yanping Sun, Lei Xian, Haonan Xing, Jiankun Yu, Zhen Yang, Tianzhi Yang, Li Yang & Pingtian Ding. (2016) Factors influencing the nuclear targeting ability of nuclear localization signals. Journal of Drug Targeting 24:10, pages 927-933.
Read now

Articles from other publishers (37)

Susanne K. Wiedmer & Marja-Liisa Riekkola. (2023) Field-flow fractionation - an excellent tool for fractionation, isolation and/or purification of biomacromolecules. Journal of Chromatography A 1712, pages 464492.
Crossref
Saurav Kumar Jha, Mohammad Imran, Laxmi Akhileshwar Jha, Nazeer Hasan, Vijay Kumar Panthi, Keshav Raj Paudel, Waleed H. Almalki, Yousuf Mohammed & Prashant Kesharwani. (2023) A Comprehensive review on Pharmacokinetic Studies of Vaccines: Impact of delivery route, carrier-and its modulation on immune response. Environmental Research 236, pages 116823.
Crossref
Sayoni Maitra Roy, Vrinda Garg, Sushmitha Pedugu Sivaraman, Sourav Barman, Chitrita Ghosh, Pousali Bag, Palanivelmurugan Mohanasundaram, Partha Sona Maji, Arnab Basu, Anjaneyulu Dirisala, Surya K. Ghosh & Amit Ranjan Maity. (2023) Overcoming the barriers of nuclear-targeted drug delivery using nanomedicine-based strategies for enhanced anticancer therapy. Journal of Drug Delivery Science and Technology 83, pages 104408.
Crossref
Peter R. Corridon. (2023) Still finding ways to augment the existing management of acute and chronic kidney diseases with targeted gene and cell therapies: Opportunities and hurdles. Frontiers in Medicine 10.
Crossref
Konstantinos AnastassakisKonstantinos Anastassakis. 2023. Androgenetic Alopecia From A to Z. Androgenetic Alopecia From A to Z 625 637 .
Smrithi Padmakumar, Anisha D'Souza, Neha N. Parayath, Benjamin S. Bleier & Mansoor M. Amiji. (2022) Nucleic acid therapies for CNS diseases: Pathophysiology, targets, barriers, and delivery strategies. Journal of Controlled Release 352, pages 121-145.
Crossref
Jingjing Yang, Anthony Griffin, Zhe Qiang & Jie Ren. (2022) Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology. Signal Transduction and Targeted Therapy 7:1.
Crossref
Li-Min Zhai, Yan Zhao, Rui-Lin Xiao, Shi-Quan Zhang, Bao-Hua Tian, Xin-Xin Li, Rong Zhang, Ri-Sheng Ma & Hai-Xia Liang. (2022) Nuclear-targeted carbon quantum dot mediated CRISPR/Cas9 delivery for fluorescence visualization and efficient editing. Nanoscale 14:39, pages 14645-14660.
Crossref
Chengyun Yan, Jiwei Gu, Yuan Zhang, Kailun Ma & Robert J. Lee. (2022) Efficient delivery of the Bcl-2 antisense oligonucleotide G3139 via nucleus-targeted aCD33-NKSN nanoparticles. International Journal of Pharmaceutics 625, pages 122074.
Crossref
Shabnam Tarvirdipour, Michal Skowicki, Cora-Ann Schoenenberger, Larisa E. Kapinos, Roderick Y. H. Lim, Yaakov Benenson & Cornelia G. Palivan. (2022) A self-assembling peptidic platform to boost the cellular uptake and nuclear delivery of oligonucleotides. Biomaterials Science 10:15, pages 4309-4323.
Crossref
Moustafa T. Mabrouk, Wei‐Chiao Huang, Luis Martinez‐Sobrido & Jonathan F. Lovell. (2022) Advanced Materials for SARS‐CoV‐2 Vaccines. Advanced Materials 34:12.
Crossref
Mahmoud A. Younis, Hesham M. Tawfeek, Ahmed A.H. Abdellatif, Jelan A. Abdel-Aleem & Hideyoshi Harashima. (2022) Clinical translation of nanomedicines: Challenges, opportunities, and keys. Advanced Drug Delivery Reviews 181, pages 114083.
Crossref
Vaishali Chugh, K. Vijaya Krishna & Abhay Pandit. (2021) Cell Membrane-Coated Mimics: A Methodological Approach for Fabrication, Characterization for Therapeutic Applications, and Challenges for Clinical Translation. ACS Nano 15:11, pages 17080-17123.
Crossref
Naomi M. Hamelmann, Jan-Willem D. Paats & Jos M. J. Paulusse. (2021) Cytosolic Delivery of Single-Chain Polymer Nanoparticles. ACS Macro Letters 10:11, pages 1443-1449.
Crossref
Sai H. S. Boddu, Prakash Bhagav, Pradeep K. Karla, Shery Jacob, Mansi D. Adatiya, Tejas M. Dhameliya, Ketan M. Ranch & Amit K. Tiwari. (2021) Polyamide/Poly(Amino Acid) Polymers for Drug Delivery. Journal of Functional Biomaterials 12:4, pages 58.
Crossref
Samar M. Shahen, Mohamed R. Mohamed, Moustafa R. K. Ali, Rehab M. Samaka, Germine M. Hamdy & Roba M. Talaat. (2021) Therapeutic potential of targeted‐gold nanospheres on collagen‐induced arthritis in rats. Clinical and Experimental Pharmacology and Physiology 48:10, pages 1346-1357.
Crossref
Ramya Kumar, Cristiam F. Santa Chalarca, Matthew R. Bockman, Craig Van Bruggen, Christian J. Grimme, Rishad J. Dalal, Mckenna G. Hanson, Joseph K. Hexum & Theresa M. Reineke. (2021) Polymeric Delivery of Therapeutic Nucleic Acids. Chemical Reviews 121:18, pages 11527-11652.
Crossref
Shabnam Tarvirdipour, Michal Skowicki, Cora-Ann Schoenenberger & Cornelia G. Palivan. (2021) Peptide-Assisted Nucleic Acid Delivery Systems on the Rise. International Journal of Molecular Sciences 22:16, pages 9092.
Crossref
Timofey Pylaev, Elena Avdeeva & Nikolai Khlebtsov. (2021) Plasmonic nanoparticles and nucleic acids hybrids for targeted gene delivery, bioimaging, and molecular recognition. Journal of Innovative Optical Health Sciences 14:04.
Crossref
Gayathri R. Ediriweera, Liyu Chen, Justin J. Yerbury, Kristofer J. Thurecht & Kara L. Vine. (2021) Non-Viral Vector-Mediated Gene Therapy for ALS: Challenges and Future Perspectives. Molecular Pharmaceutics 18:6, pages 2142-2160.
Crossref
Jing-Bo Ma, Jian-Min Shen, Ting Yue, Zi-Yan Wu & Xiao-Li Zhang. (2021) Size-shrinkable and protein kinase Cα-recognizable nanoparticles for deep tumor penetration and cellular internalization. European Journal of Pharmaceutical Sciences 159, pages 105693.
Crossref
Hua Gong, Qiangzhe Zhang, Anvita Komarla, Shuyan Wang, Yaou Duan, Zhidong Zhou, Fang Chen, Ronnie H. Fang, Sheng Xu, Weiwei Gao & Liangfang Zhang. (2021) Nanomaterial Biointerfacing via Mitochondrial Membrane Coating for Targeted Detoxification and Molecular Detection. Nano Letters 21:6, pages 2603-2609.
Crossref
Giulia Paci, Joana Caria & Edward A. Lemke. (2021) Cargo transport through the nuclear pore complex at a glance. Journal of Cell Science 134:2.
Crossref
Garima Shrivastava, Hamid A. Bakshi, Alaa A. Aljabali, Vijay Mishra, Faruck L. Hakkim, Nitin B. Charbe, Prashant Kesharwani, Dinesh K. Chellappan, Kamal Dua & Murtaza M. Tambuwala. (2020) Nucleic Acid Aptamers as a Potential Nucleus Targeted Drug Delivery System. Current Drug Delivery 17:2, pages 101-111.
Crossref
Shoichiro Asayama. (2020) Molecular Design of Polymer-based Carriers for Plasmid DNA Delivery In Vitro and In Vivo . Chemistry Letters 49:1, pages 1-9.
Crossref
Rong Ni, Ruilu Feng & Ying Chau. (2019) Synthetic Approaches for Nucleic Acid Delivery: Choosing the Right Carriers. Life 9:3, pages 59.
Crossref
Tobias Killian, Annette Buntz, Teresa Herlet, Heike Seul, Olaf Mundigl, Gernot Längst & Ulrich Brinkmann. (2019) Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids. Nucleic Acids Research 47:10, pages e55-e55.
Crossref
Qiao Zhang, Fangzheng Yu, Ming Lei, Huili Fu, Guoping Yan & Liang Li. (2019) Synthesis, Characterization, and Evaluation of Disulfide-Containing Polyethylenimine Derivative Functionalized Magnetic Carbon Nanotubes as an Efficient Gene Vector. Journal of Nanomaterials 2019, pages 1-11.
Crossref
Arunachalam Muthuraman, Seema Mehdi & Narahari Rishitha. 2019. Nanoparticles in Pharmacotherapy. Nanoparticles in Pharmacotherapy 73 112 .
Jacob A. Poliskey, Samuel T. Crowley, Raghu Ramanathan, Christopher W. White, Basil Mathew & Kevin G. Rice. (2018) Metabolically stabilized double-stranded mRNA polyplexes. Gene Therapy 25:7, pages 473-484.
Crossref
Mikhail Durymanov & Joshua Reineke. (2018) Non-viral Delivery of Nucleic Acids: Insight Into Mechanisms of Overcoming Intracellular Barriers. Frontiers in Pharmacology 9.
Crossref
Mariana Magalhães, Ana Figueiras & Francisco Veiga. 2018. Design and Development of New Nanocarriers. Design and Development of New Nanocarriers 257 291 .
Jin Tao, Wei-Feng Ding, Xiao-Hang Che, Yi-Chen Chen, Fang Chen, Xiao-Dong Chen, Xiao-Lei Ye & Su-Bin Xiong. (2016) Optimization of a cationic liposome-based gene delivery system for the application of miR-145 in anticancer therapeutics. International Journal of Molecular Medicine.
Crossref
Lin Xiong, Xin Du, Freddy Kleitz & Shi Zhang Qiao. (2015) Cancer-Cell-Specific Nuclear-Targeted Drug Delivery by Dual-Ligand-Modified Mesoporous Silica Nanoparticles. Small 11:44, pages 5919-5926.
Crossref
Bo Zhang, Xin-peng Ma, Mei-hua Sui, Edward Van Kirk, William J. Murdoch, Maciej Radosz, Neng-ming Lin & You-qing Shen. (2015) Guanidinoamidized linear polyethyleneimine for gene delivery. Chinese Journal of Polymer Science 33:6, pages 908-919.
Crossref
Jie Tang, Li Li, Christopher B. Howard, Stephen M. Mahler, Leaf Huang & Zhi Ping Xu. (2015) Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells. Journal of Materials Chemistry B 3:33, pages 6805-6812.
Crossref
Chao Liu, Leiying Miao, Weibin Sun, Xiaonan Wu, Fuhua Yan, Hongchen Sun & Changyu Zheng. (2014) Assessment of Transfection of AdCMV-EGFP to Rat Submandibular Gland Cells. Cell Biochemistry and Biophysics 71:1, pages 147-153.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.