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Hypertension in Pregnancy Volume 32, 2013 - Issue 1
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Research Article

Effect of l-Arginine Supplementation on Blood Pressure in Pregnant Women: A Meta-Analysis of Placebo-Controlled Trials

Qing ZhuKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
,
Xin YueKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
,
Qing-Yin TianKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
,
Gaowa SarenKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
,
Ming-Hui WuKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
,
Yun ZhangKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR China
&
Tong-Tao LiuKey Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Jinan, PR China;Department of Cardiology, QiLu Hospital, Shandong University, Jinan, PR ChinaCorrespondence[email protected]
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Pages 32-41 | Published online: 07 Sep 2012

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Daniela Menichini, Lia Feliciello, Isabella Neri & Fabio Facchinetti. (2023) L-Arginine supplementation in pregnancy: a systematic review of maternal and fetal outcomes. The Journal of Maternal-Fetal & Neonatal Medicine 36:1.
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Hiroko Maruki-Uchida, Masahiko Sai, Shoichiro Yano, Minoru Morita & Kazuhisa Maeda. (2020) Amazake made from sake cake and rice koji suppresses sebum content in differentiated hamster sebocytes and improves skin properties in humans. Bioscience, Biotechnology, and Biochemistry 84:8, pages 1689-1695.
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Parvin Mirmiran, Zahra Bahadoran, Khosrow Kashfi & Asghar Ghasemi. 2022. The Role of Nitric Oxide in Type 2 Diabetes. The Role of Nitric Oxide in Type 2 Diabetes 260 283 .
Temitayo Olabisi Ajibade, Olusola Adedayo Awodele, Monsuru Oladunjoye Tijani, Olumuyiwa Abiola Adejumobi, Moses Olusola Adetona, Ademola Adetokunbo Oyagbemi, Aduragbenro Deborah Adedapo, Temidayo Olutayo Omobowale, Abimbola Obemisola Aro, Olufunke Eunice Ola-Davies, Adebowale Benard Saba, Adeolu Alex Adedapo, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Oluwafemi Omoniyi Oguntibeju & Momoh Audu Yakubu. (2022) L-arginine and lisinopril supplementation protects against sodium fluoride–induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity. Environmental Science and Pollution Research 30:9, pages 23263-23275.
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Lianbin Xu, Xinhui Wang, Chaochen Wang, Wenyuan Li & Hongyun Liu. (2022) l-arginine supplementation improved neonatal outcomes in pregnancies with hypertensive disorder or intrauterine growth restriction: A systematic review and meta-analysis of randomized controlled trials. Clinical Nutrition 41:7, pages 1512-1522.
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Eita Goto. (2021) Effects of prenatal oral l-arginine on birth outcomes: a meta-analysis. Scientific Reports 11:1.
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Hongyu Li, Qisijing Liu, Zhiyong Zou, Qiao Chen, Wanzhou Wang, Andrea A. Baccarelli, Furong Deng, Xinbiao Guo & Shaowei Wu. (2021) L-arginine supplementation to mitigate cardiovascular effects of walking outside in the context of traffic-related air pollution in participants with elevated blood pressure: A randomized, double-blind, placebo-controlled trial. Environment International 156, pages 106631.
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Zahra Bahadoran, Parvin Mirmiran, Khosrow Kashfi & Asghar Ghasemi. (2020) Endogenous flux of nitric oxide: Citrulline is preferred to Arginine. Acta Physiologica 231:3.
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Mohammad Zeinali Khosroshahi, Omid Asbaghi, Sajjad Moradi, Mahnaz Rezaei kelishadi, Mojtaba Kaviani, Mahnaz Mardani & Cyrus Jalili. (2020) The effects of supplementation with L-arginine on anthropometric indices and body composition in overweight or obese subjects: A systematic review and meta-analysis. Journal of Functional Foods 71, pages 104022.
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Kamesh Venkatakrishnan, Hui-Fang Chiu & Chin-Kun Wang. (2020) Impact of functional foods and nutraceuticals on high blood pressure with a special focus on meta-analysis: review from a public health perspective. Food & Function 11:4, pages 2792-2804.
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Hui-Fang Chiu, Kamesh Venkatakrishnan & Chin-Kun Wang. 2020. Dietary Sugar, Salt and Fat in Human Health. Dietary Sugar, Salt and Fat in Human Health 423 450 .
Andrea M Weckman, Chloe R McDonald, Jo-Anna B Baxter, Wafaie W Fawzi, Andrea L Conroy & Kevin C Kain. (2019) Perspective: L-arginine and L-citrulline Supplementation in Pregnancy: A Potential Strategy to Improve Birth Outcomes in Low-Resource Settings. Advances in Nutrition 10:5, pages 765-777.
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A.P. Arikawe, I.C. Udenze, A.W. Olusanya, O.A. Akinnibosun, I. Dike & B.N. Duru. (2019) L-arginine supplementation lowers blood pressure, protein excretion and plasma lipid profile in experimental salt-induced hypertension in pregnancy: Relevance to preeclampsia. Pathophysiology 26:3-4, pages 191-197.
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Joshua A. Beckman, Shelley Hurwitz & Naomi D.L. Fisher. (2018) Arginine impairs endothelial and executive function in older subjects with cardiovascular risk. Journal of the American Society of Hypertension 12:10, pages 723-731.
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Jonathan M. Greene & Peter L. Ryan. 2017. L-Arginine in Clinical Nutrition. L-Arginine in Clinical Nutrition 285 299 .
Marc P. McRae. (2016) Therapeutic Benefits of l-Arginine: An Umbrella Review of Meta-analyses. Journal of Chiropractic Medicine 15:3, pages 184-189.
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