343
Views
21
CrossRef citations to date
0
Altmetric
Research Article

P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells

, , , , , , , & show all
Pages 1082-1092 | Received 11 Mar 2012, Accepted 24 Apr 2012, Published online: 18 May 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Fengyin Liang, Fengjuan Su, Xiaoxiao Wang, Simei Long, Yinglin Zheng, Xiaofei He, Jiyan Pang & Zhong Pei. (2019) Xyloketal derivative C53N protects against mild traumatic brain injury in mice. Drug Design, Development and Therapy 13, pages 173-182.
Read now
Yang Yu, Lan-fang Li, Jing Tao, Xiao-mian Zhou & Cheng Xu. (2019) Silibinin induced apoptosis of human epidermal cancer A431 cells by promoting mitochondrial NOS. Free Radical Research 53:7, pages 714-726.
Read now

Articles from other publishers (19)

Bodo C. Melnik. (2023) Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment. Cells 12:22, pages 2600.
Crossref
Ayantika Sengupta, Subhamoy Chakraborty, Sampurna Datta & Sanjay Ghosh. 2023. Nitric Oxide: From Research to Therapeutics. Nitric Oxide: From Research to Therapeutics 177 210 .
Wei-wei Liu, Fang Wang, Can Li, Xiao-yu Song, Wuxiyar Otkur, Yu-ying Zhu, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki & Takashi Ikejima. (2021) Silibinin relieves UVB-induced apoptosis of human skin cells by inhibiting the YAP-p73 pathway. Acta Pharmacologica Sinica 43:8, pages 2156-2167.
Crossref
Ying Jiang, Mengna Ding, Lang Liu, Jianguo Cao, Liuhong Chen, Guozheng Huang, Yuning Huo & Xiling Dai. (2022) Antibacterial effect of Cu2O/TiO2 photocatalytic composite on Pseudomonas marginalis pv. marginalis. Archives of Microbiology 204:8.
Crossref
Ting Liu, Li Sun, Yubin Zhang, Yonglin Wang & Jiang Zheng. (2021) Imbalanced GSH/ROS and sequential cell death. Journal of Biochemical and Molecular Toxicology 36:1.
Crossref
Zhen-Jie Wang, Shao-Meng Yu, Jiang-Mei Gao, Peng Zhang, Geoff Hide, Masahiro Yamamoto, De-Hua Lai & Zhao-Rong Lun. (2021) High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase knockout rats. iScience 24:11, pages 103280.
Crossref
Meizhu He, Lijie Xia & Jinyao Li. (2021) Potential Mechanisms of Plant-Derived Natural Products in the Treatment of Cervical Cancer. Biomolecules 11:10, pages 1539.
Crossref
Hardeep Singh Tuli, Sonam Mittal, Diwakar Aggarwal, Gaurav Parashar, Nidarshana Chaturvedi Parashar, Sushil Kumar Upadhyay, Tushar Singh Barwal, Aklank Jain, Ginpreet Kaur, Raj Savla, Katrin Sak, Manoj Kumar, Mehmet Varol, Ashif Iqubal & Anil Kumar Sharma. (2021) Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance. Seminars in Cancer Biology 73, pages 196-218.
Crossref
Xin Wang, Zhen Zhang & Shuai-Cheng Wu. (2020) Health Benefits of Silybum marianum : Phytochemistry, Pharmacology, and Applications . Journal of Agricultural and Food Chemistry 68:42, pages 11644-11664.
Crossref
Chongcheng Wang, Chuan He, Shan Lu, Xuanzhong Wang, Lei Wang, Shipeng Liang, Xinyu Wang, Meihua Piao, Jiayue Cui, Guangfan Chi & Pengfei Ge. (2020) Autophagy activated by silibinin contributes to glioma cell death via induction of oxidative stress-mediated BNIP3-dependent nuclear translocation of AIF. Cell Death & Disease 11:8.
Crossref
Dominique Delmas, Jianbo Xiao, Anne Vejux & Virginie Aires. (2020) Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity. Molecules 25:9, pages 2009.
Crossref
Tatiane M. B. Barros, Ana P. B. Lima, Tamires C. Almeida & Glenda N. Silva. (2020) Inhibition of urinary bladder cancer cell proliferation by silibinin. Environmental and Molecular Mutagenesis 61:4, pages 445-455.
Crossref
Guo-Dong Yao, Meng-Yao Ge, Dan-Qi Li, Ling Chen, Toshihiko Hayashi, Shin-ichi Tashiro, Satoshi Onodera, Chun Guo, Shao-Jiang Song & Takashi Ikejima. (2018) L-A03, a dihydroartemisinin derivative, promotes apoptotic cell death of human breast cancer MCF-7 cells by targeting c-Jun N-terminal kinase. Biomedicine & Pharmacotherapy 105, pages 320-325.
Crossref
Jia-Yi Cai, Jian Li, Yong-Na Hou, Kai Ma, Guo-Dong Yao, Wei-Wei Liu, Toshihiko Hayashi, Kikuji Itoh, Shin-ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2018) Concentration-dependent dual effects of silibinin on kanamycin-induced cells death in Staphylococcus aureus. Biomedicine & Pharmacotherapy 102, pages 782-791.
Crossref
Joaquim Bosch-Barrera, Bernardo Queralt & Javier A. Menendez. (2017) Targeting STAT3 with silibinin to improve cancer therapeutics. Cancer Treatment Reviews 58, pages 61-69.
Crossref
Guodong Yao, Hao Chen, Ling Chen, Mengyao Ge, Jing Yang, Weiwei Liu, Mingyu Xia, Toshihiko Hayashi, Chun Guo & Takashi Ikejima. (2017) Autophagy promotes apoptosis induction through repressed nitric oxide generation in the treatment of human breast cancer MCF-7 cells with L-A03, a dihydroartemisinin derivative. Medicinal Chemistry Research 26:7, pages 1427-1436.
Crossref
Yali Zhang, Huanhuan Dong, Jingfang Zhang & Liyu Zhang. (2017) Inhibitory effect of hyperoside isolated from Zanthoxylum bungeanum leaves on SW620 human colorectal cancer cells via induction of the p53 signaling pathway and apoptosis. Molecular Medicine Reports 16:2, pages 1125-1132.
Crossref
Nan Zheng, Lu Liu, Wei-wei Liu, Fei Li, Toshihiko Hayashi, Shin-ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2016) Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacologica Sinica 38:2, pages 277-289.
Crossref
YAN JIANG, HANJIE XU & JIAFEI WANG. (2016) Alantolactone induces apoptosis of human cervical cancer cells via reactive oxygen species generation, glutathione depletion and inhibition of the Bcl-2/Bax signaling pathway. Oncology Letters 11:6, pages 4203-4207.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.