P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells

References

• Liu B, Yang P, Ye Y, Zhou Y, Li L, Tashiro S, . Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells. Free Radic Res 2011;45:835–847.
   PubMed Web of Science ®Google Scholar
• Han YH, Park WH. Pyrogallol-induced As4.1 juxtaglomerular cell death is attenuated by MAPK inhibitors via preventing GSH depletion. Arch Toxicol 2010;84:631–640.
   PubMedGoogle Scholar
• El-Assaad W, Kozhaya L, Araysi S, Panjarian S, Bitar FF, Baz E, . Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells. Biochem J 2003;376:725–732.
   PubMedGoogle Scholar
• Fan S, Qi M, Yu Y, Li L, Yao G, Tashiro SI, . P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK. Free Radic Res 2012 Feb 2 [Epub ahead of print].
   Google Scholar
• Fan S, Li L, Chen S, Yu Y, Qi M, Tashiro SI, . Silibinin induced-autophagic and apoptotic death is associated with ROS and RNS increase in HeLa cells. Free Radic Res 2011;45:1307–1324.
   PubMed Web of Science ®Google Scholar
• Mira L, Silva M, Manso CF. Scavenging of reactive oxygen species by silibinin dihemisuccinate. Biochem Pharmacol. 1994;48:753–759.
   PubMed Web of Science ®Google Scholar
• Lu P, Mamiya T, Lu LL, Mouri A, Zou L, Nagai T, . Silibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice. Br J Pharmacol 2009;157:1270–1277.
   PubMed Web of Science ®Google Scholar
• Duan W, Jin X, Li Q, Tashiro S, Onodera S, Ikejima T. Silibinin induced autophagic and apoptotic cell death in HT1080 cells through a reactive oxygen species pathway. J Pharmacol Sci 113;1:48–56.
   PubMedGoogle Scholar
• Wang HJ, Jiang YY, Wei XF, Huang H, Tashiro S, Onodera S, . Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells. Free Radic Res 44;1: 90–100.
   PubMedGoogle Scholar
• Jiang YY, Huang H, Wang HJ, Wu D, Yang R, Tashiro S, . Interruption of mitochondrial complex IV activity and cytochrome c expression activated O2 - mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways. Eur J Pharmacol 20111;668:78–87.
   Google Scholar
• Wang HJ, Wei XF, Jiang YY, Huang H, Yang Y, Fan SM, . Silibinin induces the generation of nitric oxide in human breast cancer MCF-7 cells. Free Radic Res 2010;44: 577–584.
   PubMed Web of Science ®Google Scholar
• Bannwart CF, Nakaira-Takahagi E, Golim MA, de Medeiros LT, Romão M, Weel IC, . Downregulation of nuclear factor-kappa B (NF-kappaB) pathway by silibinin in human monocytes challenged with Paracoccidioides brasiliensis. Life Sci 2010;86:880–886.
   PubMed Web of Science ®Google Scholar
• Iovine NM, Pursnani S, Voldman A, Wasserman G, Blaser MJ, Weinrauch Y. Reactive nitrogen species contribute to innate host defense against Campylobacter jejuni. Infect Immun 2008;76:986–993.
   PubMed Web of Science ®Google Scholar
• Reid MB, Durham WJ. Generation of reactive oxygen and nitrogen species in contracting skeletal muscle: potential impact on aging. Ann N Y Acad Sci 2002;959:108–116.
   PubMed Web of Science ®Google Scholar
• Powers SK, Talbert EE, Adhihetty PJ. Reactive oxygen and nitrogen species as intracellular signals in skeletal muscle. J Physiol 2011;589:2129–2138.
   PubMed Web of Science ®Google Scholar
• Aquilano K, Baldelli S, Cardaci S, Rotilio G, Ciriolo MR. Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells. J Cell Sci 2011;124:1043–1054.
   PubMed Web of Science ®Google Scholar
• Guha P, Dey A, Sen R, Chatterjee M, Chattopadhyay S, Bandyopadhyay SK. Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line. J Pharmacol Exp Ther 2011; 336:206–214.
   PubMed Web of Science ®Google Scholar
• Park BC, Park SH, Paek SH, Park SY, Kwak MK, Choi HG, . Chloroquine-induced nitric oxide increase and cell death is dependent on cellular GSH depletion in A172 human glioblastoma cells. Toxicol Lett 2008;178:52–60.
   PubMed Web of Science ®Google Scholar
• Tokuzumi S, Hori M, Monobe M, Hosoi Y, Kojima S. Effect of nitric oxide on gamma-ray-induced micronucleus frequency in RAW264.7 cells. Radiat Res 2005;164:723–732.
   PubMedGoogle Scholar
• Friederich JA, Butterworth JF 4th. Sodium nitroprusside: twenty years and counting. Anesth Analg 1995;81:152–162.
   PubMed Web of Science ®Google Scholar
• Kühn K, Lotz M. Mechanisms of sodium nitroprusside-induced death in human chondrocytes. Rheumatol Int 23:241–247.
   PubMedGoogle Scholar
• Gui J, Song Y, Reena Han N-L, Sheu F-S. Characterisation of transcriptional regulation of neurogranin by nitric oxide and the role of neurogranin in SNP-induced cell death: implication of neurogranin in an increased neuronal susceptibility to oxidative stress. Int J Biol Sci 2007;3:212–224.
   PubMed Web of Science ®Google Scholar
• Pytlowany M, Strosznajder JB, Jęśko H, Cąkała M, Strosznajder RP. Molecular mechanism of PC12 cell death evoked by sodiumnitroprusside, a nitric oxide donor. Acta Biochimica Polonica 2008;55:339–347.
   PubMed Web of Science ®Google Scholar
• Brüne B. The intimate relation between nitric oxide and superoxide in apoptosis and cell survival. Antioxid Redox Signal 2005;7:497–507.
   PubMed Web of Science ®Google Scholar
• Grisham MB, Jourd'Heuil D, Wink DA. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Am J Physiol 1999;276:G315–G321.
   PubMed Web of Science ®Google Scholar
• Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000;87: 840–844.
   PubMed Web of Science ®Google Scholar
• Anasagasti MJ, Martin JJ, Mendoza L, Obrador E, Estrela JM, McCuskey RS, . Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature. Hepatology 1998;27:1249–1256.
   PubMed Web of Science ®Google Scholar
• Franco R, Cidlowski JA. Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 2009;16:1303–1314.
   PubMed Web of Science ®Google Scholar
• da Costa PE, Batista WL, Curcio MF, Moraes MS, Borges RE, Nascimento PA, . Protein tyrosine phosphatase alpha regulates cell detachment and cell death profiles induced by nitric oxide donors in the A431 human carcinoma cell line. Redox Rep 2011;16:27–37.
   PubMed Web of Science ®Google Scholar