282
Views
39
CrossRef citations to date
0
Altmetric
Research Article

The role of melatonin as an antioxidant in human lens epithelial cells

, , , , , & show all
Pages 635-642 | Received 23 Feb 2013, Accepted 22 May 2013, Published online: 20 Jun 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Lisa A Ostrin. (2019) Ocular and systemic melatonin and the influence of light exposure. Clinical and Experimental Optometry 102:2, pages 99-108.
Read now
Bing Liang, Wei Wei, Jianta Wang, Mingming Zhang, Ran Xu, Fei Wu, Haitao Xiao & Lei Tang. (2016) Protective effects of Semiaquilegia adoxoides n-butanol extract against hydrogen peroxide-induced oxidative stress in human lens epithelial cells. Pharmaceutical Biology 54:9, pages 1656-1663.
Read now
Jean A Boutin. (2016) Quinone reductase 2 as a promising target of melatonin therapeutic actions. Expert Opinion on Therapeutic Targets 20:3, pages 303-317.
Read now
O. Ozsoy, F. B. Yildirim, E. Ogut, Y. Kaya, G. Tanriover, H. Parlak, A. Agar & M. Aslan. (2015) Melatonin is protective against 6-hydroxydopamine-induced oxidative stress in a hemiparkinsonian rat model. Free Radical Research 49:8, pages 1004-1014.
Read now
Sarika Singh, Kumar Vyonkesh Mani & Neeru Kapoor. (2015) Effect of occupational EMF exposure from radar at two different frequency bands on plasma melatonin and serotonin levels. International Journal of Radiation Biology 91:5, pages 426-434.
Read now

Articles from other publishers (34)

Yuxiang Liang, Ying Wang, Xiao Zhang, Shanshan Jin, Yuqian Guo, Zhaowei Yu, Xinrui Xu, Qizhi Shuai, Zihan Feng, Binghong Chen, Ting Liang, Ruifang Ao, Jianting Li, Juan Zhang, Rui Cao, Hong Zhao, Zhaoyang Chen, Zhizhen Liu & Jun Xie. (2023) Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress. Acta Biochimica et Biophysica Sinica.
Crossref
Anna Bendarska-Czerwińska, Nikola Zmarzły, Emilia Morawiec, Agata Panfil, Kamil Bryś, Justyna Czarniecka, Aleksander Ostenda, Konrad Dziobek, Dorota Sagan, Dariusz Boroń, Piotr Michalski, Veronica Pallazo-Michalska & Beniamin Oskar Grabarek. (2023) Endocrine disorders and fertility and pregnancy: An update. Frontiers in Endocrinology 13.
Crossref
Yu Mi, Chaoqun Wei, Liyao Sun, Huirui Liu, Jiayue Zhang, Jialin Luo, Xiaohan Yu, Jie He, Hongyan Ge & Ping Liu. (2023) Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways. Biomedicine & Pharmacotherapy 157, pages 114048.
Crossref
Morteza Akhzari, Mahdi Barazesh & Sajad Jalili. (2022) Melatonin As An Antioxidant Agent In Disease Prevention: A Biochemical Focus. Letters in Organic Chemistry 19:11, pages 958-975.
Crossref
Lixiong Gao, Ni Jin, Zi Ye, Tianju Ma, Yang Huang, Hongyu Li, Jinlin Du & Zhaohui Li. (2022) A possible connection between reactive oxygen species and the unfolded protein response in lens development: From insight to foresight. Frontiers in Cell and Developmental Biology 10.
Crossref
Tianke Yang, Xiaolei Lin, Hongzhe Li, Xiyue Zhou, Fan Fan, Jianing Yang, Yi Luo & Xin Liu. (2022) Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling. Frontiers in Pharmacology 13.
Crossref
Shuyu Liu, Zi Jin, Ruyue Xia, Zhuoni Zheng, Yi Zha, Qiang Wang, Xinbei Wan, Hui Yang & Jianqiu Cai. (2022) Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway. Oxidative Medicine and Cellular Longevity 2022, pages 1-13.
Crossref
Victoria Eugenia Lledó, Hanan Awad Alkozi, Juan Sánchez-Naves, Miguel Angel Fernandez-Torres & Ana Guzman-Aranguez. (2022) Melatonin counteracts oxidative damage in lens by regulation of Nrf2 and NLRP3 inflammasome activity. Experimental Eye Research 215, pages 108912.
Crossref
Tayler F.L. Wishart, Mary Flokis, Daisy Y. Shu, Shannon J. Das & Frank J. Lovicu. (2021) Hallmarks of lens aging and cataractogenesis. Experimental Eye Research 210, pages 108709.
Crossref
Victoria Eugenia Lledó, Hanan Awad Alkozi, Juan Sánchez-Naves, Miguel Angel Fernandez-Torres & Ana Guzman-Aranguez. (2021) Modulation of aqueous humor melatonin levels by yellow-filter and its protective effect on lens. Journal of Photochemistry and Photobiology B: Biology 221, pages 112248.
Crossref
N. S. Khodzhaev, A. A. Stadnikov, A. D. Chuprov, S. M. Kim & O. V. Marshinskaya. (2021) Role of Melatonin in Human Eye Physiology and Its Implications for Ophthalmic Diseases Treatment (Review). Ophthalmology in Russia 18:2, pages 234-239.
Crossref
Jiayue Zhou, Jing Wu, Sifan Zheng, Xiangjun Chen, Daizhan Zhou & Xingchao Shentu. (2021) Integrated Transcriptomic and Proteomic Analysis Reveals Up-Regulation of Apoptosis and Small Heat Shock Proteins in Lens of Rats Under Low Temperature. Frontiers in Physiology 12.
Crossref
Qianqian Wu, Lijun Fang, Youjing Yang, Aiqing Wang, Xiaoyu Chen, Jiaojiao Sun, Jianmei Wan, Chengjiao Hong, Jian Tong, Shasha Tao & Hailin Tian. (2020) Protection of melatonin against long‐term radon exposure‐caused lung injury. Environmental Toxicology 36:4, pages 472-483.
Crossref
OloruntobiOluwasegun Maliki, AbdullateefIsiaka Alagbonsi, ComfortMoyinoluwa Ibitoye & LuqmanAribidesi Olayaki. (2021) Melatonin and Vitamin C modulate cassava diet-induced alteration in reproductive and thyroid functions. Nigerian Journal of Experimental and Clinical Biosciences 9:3, pages 133.
Crossref
Ruobing Wang, Yahui Liu, Xuguang Mi, Qingmin Chen, Peiqiang Jiang, Junjie Hou, Yifan Lin, Siqi Li, Bai Ji & Yanqiu Fang. (2020) Sirt3 promotes hepatocellular carcinoma cells sensitivity to regorafenib through the acceleration of mitochondrial dysfunction. Archives of Biochemistry and Biophysics 689, pages 108415.
Crossref
Qianyi Deng, Qin Liu, Huini Zhang, Wenguo Fan, Jingzhou Li, Jun Kang, Hongwen He & Fang Huang. (2019) Melatonin enhances hydrogen peroxide-induced apoptosis in human dental pulp cells. Journal of Dental Sciences 14:4, pages 370-377.
Crossref
Jesús Pintor. (2018) Pharmacology without drugs. Journal of Optometry 11:4, pages 201-202.
Crossref
Almudena Crooke, Fernando Huete-Toral, Basilio Colligris & Jesús Pintor. (2017) The role and therapeutic potential of melatonin in age-related ocular diseases. Journal of Pineal Research 63:2, pages e12430.
Crossref
Alfredo Ramírez-Reveco, Franz Villarroel-Espíndola, Joan E. Rodríguez-Gil & Ilona I. Concha. (2017) Neuronal signaling repertoire in the mammalian sperm functionality. Biology of Reproduction 96:3, pages 505-524.
Crossref
Hanan Awad Alkozi, Xiaoyu Wang, Maria J. Perez de Lara & Jesus Pintor. (2017) Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis. Experimental Eye Research 154, pages 168-176.
Crossref
Ramón Soto-Vázquez, Carlos Labastida-López, Samuel Romero-Castello, Gloria Benítez-King & Patricia Parra-Cervantes. (2016) Stimulation of dendrogenesis and neural maturation in adult mammals. Pharmaceutical Patent Analyst 5:3, pages 183-193.
Crossref
WEN-SHENG DENG, QING XU, YE LIU, CHUN-HUI JIANG, HONG ZHOU & LEI GU. (2016) Effects of melatonin on liver function and lipid peroxidation in a rat model of hepatic ischemia/reperfusion injury. Experimental and Therapeutic Medicine 11:5, pages 1955-1960.
Crossref
Tianju Ma, Tingjun Chen, Peng Li, Zi Ye, Wei Zhai, Liang Jia, Wenqian Chen, Ang Sun, Yang Huang, Shihui Wei & Zhaohui Li. (2016) Heme oxygenase-1 (HO-1) protects human lens epithelial cells (SRA01/04) against hydrogen peroxide (H2O2)-induced oxidative stress and apoptosis. Experimental Eye Research 146, pages 318-329.
Crossref
Ju-Hee Lee, Ji-Hong Moon, Uddin MD. Nazim, You-Jin Lee, Jae-Won Seol, Seong-Kug Eo, John-Hwa Lee & Sang-Youel Park. (2016) Melatonin protects skin keratinocyte from hydrogen peroxide-mediated cell death via the SIRT1 pathway . Oncotarget 7:11, pages 12075-12088.
Crossref
Gun Woo Son, Hana Yang, Hye Rim Park, Seung Eun Lee, Young-Ho Jin, Cheung-Seog Park & Yong Seek Park. (2016) Analysis of miRNA expression profiling in melatonin-exposured endothelial cells. Molecular & Cellular Toxicology 12:1, pages 73-81.
Crossref
Shangming Liu, Yuji Guo, Qiuhuan Yuan, Yan Pan, Liyan Wang, Qian Liu, Fuwu Wang, Jingjing Wang & Aijun Hao. (2015) Melatonin prevents neural tube defects in the offspring of diabetic pregnancy. Journal of Pineal Research 59:4, pages 508-517.
Crossref
Xiaoqi Pan, Lanlan Zhu, Huiping Lu, Dun Wang, Qing Lu & Hong Yan. (2015) Melatonin Attenuates Oxidative Damage Induced by Acrylamide In Vitro and In Vivo. Oxidative Medicine and Cellular Longevity 2015, pages 1-12.
Crossref
Shavi Fernando & Luk Rombauts. (2014) Melatonin: shedding light on infertility? - a review of the recent literature. Journal of Ovarian Research 7:1.
Crossref
Gun Woo Son, Gun-Dong Kim, Hana Yang, Hye Rim Park & Yong Seek Park. (2014) Alteration of gene expression profile by melatonin in endothelial cells. BioChip Journal 8:2, pages 91-101.
Crossref
Sara Salucci, Sabrina Burattini, Michela Battistelli, Valentina Baldassarri, Davide Curzi, Aurelio Valmori & Elisabetta Falcieri. (2014) Melatonin Prevents Chemical-Induced Haemopoietic Cell Death. International Journal of Molecular Sciences 15:4, pages 6625-6640.
Crossref
Peter Kovacic & Ratnasamy Somanathan. (2014) Melatonin and Circadian Rhythm: Aging, Cancer, and Mechanism. Open Journal of Preventive Medicine 04:07, pages 545-560.
Crossref
Juhyun Song, So Mang Kang, Won Taek Lee, Kyung Ah Park, Kyoung Min Lee & Jong Eun Lee. (2014) The Beneficial Effect of Melatonin in Brain Endothelial Cells against Oxygen-Glucose Deprivation Followed by Reperfusion-Induced Injury. Oxidative Medicine and Cellular Longevity 2014, pages 1-14.
Crossref
Amitava Dasgupta & Kimberly Klein. 2014. Antioxidants in Food, Vitamins and Supplements. Antioxidants in Food, Vitamins and Supplements 295 315 .
Rüdiger Hardeland. (2013) Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms. Journal of Pineal Research 55:4, pages 325-356.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.