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Drug Delivery Volume 18, 2011 - Issue 6
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Research Article

Thiolated polycarbophil/glutathione: Defining its potential as a permeation enhancer for oral drug administration in comparison to sodium caprate

Glen PereraDepartment of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 52, Josef-Möller-Haus, 6020 Innsbruck, Austria
,
Jan BarthelmesDepartment of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 52, Josef-Möller-Haus, 6020 Innsbruck, Austria
,
Anja VetterDepartment of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 52, Josef-Möller-Haus, 6020 Innsbruck, Austria
,
Christof KriegInstitute of Analytical Chemistry and Radiochemistry, University of Innsbruck, Innrain 52a, 6020 Innsbruck, Austria
,
Cindy UhlschmiedInstitute of Analytical Chemistry and Radiochemistry, University of Innsbruck, Innrain 52a, 6020 Innsbruck, Austria
,
Günther K. BonnInstitute of Analytical Chemistry and Radiochemistry, University of Innsbruck, Innrain 52a, 6020 Innsbruck, Austria
&
Andreas Bernkop-SchnürchDepartment of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 52, Josef-Möller-Haus, 6020 Innsbruck, AustriaCorrespondence[email protected]
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Pages 415-423 | Received 29 Nov 2010, Accepted 08 Mar 2011, Published online: 09 May 2011

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Christian Tscheik, Ingolf E. Blasig & Lars Winkler. (2013) Trends in drug delivery through tissue barriers containing tight junctions. Tissue Barriers 1:2.
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Articles from other publishers (10)

Patrick Knoll, Giuseppe Francesco Racaniello, Valentino Laquintana, Florina Veider, Ahmad Saleh, Anna Seybold, Nunzio Denora & Andreas Bernkop-Schnürch. (2023) Lipid-based nanoparticles: Enhanced cellular uptake via surface thiolation. International Journal of Pharmaceutics 635, pages 122753.
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Tielan Wei, Sachin Sunil Thakur, Mengyang Liu & Jingyuan Wen. (2022) Oral delivery of glutathione: antioxidant function, barriers and strategies. Acta Materia Medica 1:2.
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Nathalie Hock, Giuseppe Francesco Racaniello, Sam Aspinall, Nunzio Denora, Vitaliy V. Khutoryanskiy & Andreas Bernkop‐Schnürch. (2021) Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body. Advanced Science 9:1, pages 2102451.
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Christina Leichner, Max Jelkmann & Andreas Bernkop-Schnürch. (2019) Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature. Advanced Drug Delivery Reviews 151-152, pages 191-221.
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Arshad Mahmood, Sonja Bonengel, Flavia Laffleur, Muhammad Ijaz, Gintare Leonaviciute & Andreas Bernkop-Schnürch. (2015) An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers. International Journal of Pharmaceutics 496:2, pages 304-313.
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Sonja Bonengel & Andreas Bernkop-Schn?rch. (2014) Thiomers ? From bench to market. Journal of Controlled Release 195, pages 120-129.
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Erik Sjögren, Bertil Abrahamsson, Patrick Augustijns, Dieter Becker, Michael B. Bolger, Marcus Brewster, Joachim Brouwers, Talia Flanagan, Matthew Harwood, Christian Heinen, René Holm, Hans-Paul Juretschke, Marlies Kubbinga, Anders Lindahl, Viera Lukacova, Uwe Münster, Sibylle Neuhoff, Mai Anh Nguyen, Achiel van Peer, Christos Reppas, Amin Rostami Hodjegan, Christer Tannergren, Werner Weitschies, Clive Wilson, Patricia Zane, Hans Lennernäs & Peter Langguth. (2014) In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects. European Journal of Pharmaceutical Sciences 57, pages 99-151.
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Vivek Gupta, Byeong Hee Hwang, JooHee Lee, Aaron C. Anselmo, Nishit Doshi & Samir Mitragotri. (2013) Mucoadhesive intestinal devices for oral delivery of salmon calcitonin. Journal of Controlled Release 172:3, pages 753-762.
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Vivek Gupta, Byeong Hee Hwang, Nishit Doshi & Samir Mitragotri. (2013) A permeation enhancer for increasing transport of therapeutic macromolecules across the intestine. Journal of Controlled Release 172:2, pages 541-549.
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Taslim A. Al-Hilal, Farzana Alam & Youngro Byun. (2013) Oral drug delivery systems using chemical conjugates or physical complexes. Advanced Drug Delivery Reviews 65:6, pages 845-864.
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