References
- Anderberg, E.K., Lindmark, T., Artursson, P. (1993). Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route. Pharm Res. 10:857–64.
- Aungst, B.J. (2000). Intestinal permeation enhancers. J Pharm Sci. 89:429–42.
- Bernkop-Schnurch A., Schwarz V., Steininger, S. (1999). Polymers with thiol groups: a new generation of mucoadhesive polymers? Pharm Res. 16:876–81.
- Chao, A.C., Nguyen, J.V., Broughall, M., Griffin, A., Fix, J.A., Daddona, P.E. (1999). In vitro and in vivo evaluation of effects of sodium caprate on enteral peptide absorption and on mucosal morphology. Int J Pharm. 191:15–24.
- Chavanpatil, M.D., Vavia, P.R. (2005). Nasal drug delivery of sumatriptan succinate. Pharmazie. 60:347–9.
- Cho, S.Y., Kim, J.S., Li, H., Shim, C., Linhardt, R.J., Kim, Y.S. (2002). Enhancement of paracellular transport of heparin disaccharide across Caco-2 cell monolayers. Arch Pharm Res. 25:86–92.
- Ciapetti, G., Cenni, E., Pratelli, L., Pizzoferrato, A. (1993). In vitro evaluation of cell/biomaterial interaction by MTT assay. Biomaterials. 14:359–64.
- Clausen, A.E., Bernkop-Schnurch, A. (2000). In vitro evaluation of the permeation-enhancing effect of thiolated polycarbophil. J Pharm Sci. 89:1253–61.
- Clausen, A.E., Kast, C.E., Bernkop-Schnurch, A. (2002). The role of glutathione in the permeation enhancing effect of thiolated polymers. Pharm Res. 19:602–8.
- Davies, B., Morris, T. (1993). Physiological parameters in laboratory animals and humans. Pharm Res. 10:1093–5.
- Diamond, J.M. (1977). Twenty-first Bowditch lecture. The epithelial junction: bridge, gate, and fence. Physiologist. 20:10–18.
- Habeeb, A.F. (1973). A sensitive method for localization of disulfide containing peptides in column effluents. Anal Biochem. 56:60–5.
- Hayashi, M., Tomita, M., Awazu, S. (1997). Transcellular and paracellular contribution to transport processes in the colorectal route. Adv Drug Deliv Rev. 28:191–204.
- Ibrahim, S.A., Li, S.K. (2010). Efficiency of fatty acids as chemical penetration enhancers: mechanisms and structure enhancement relationship. Pharm Res. 27:115–25.
- Kast, C.E., Guggi, D., Langoth, N., Bernkop-Schnurch, A. (2003). Development and in vivo evaluation of an oral delivery system for low molecular weight heparin based on thiolated polycarbophil. Pharm Res. 20:931–6.
- Leitner, V.M., Guggi, D., Bernkop-Schnurch, A. (2004). Thiomers in noninvasive polypeptide delivery: in vitro and in vivo characterization of a polycarbophil-cysteine/glutathione gel formulation for human growth hormone. J Pharm Sci. 93:1682–91.
- Lin, X., Xu, D.S., Feng, Y., Li, S.M., Lu, Z.L., Shen, L. (2006). Release-controlling absorption enhancement of enterally administered Ophiopogon japonicus polysaccharide by sodium caprate in rats. J Pharm Sci. 95:2534–42.
- Lindmark, T., Schipper, N., Lasorova, L., De Boer, A.G., Artursson, P. (1998). Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes. J Drug Target. 5:215–23.
- Maher, S., Kennelly, R., Bzik, V.A., Baird, A.W., Wang, X., Winter, D., Brayden, D.J. (2009). Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae. Eur J Pharm Sci. 38:291–300.
- Motlekar, N.A., Srivenugopal, K.S., Wachtel, M.S., Youan, B.B. (2005). Oral delivery of low-molecular-weight heparin using sodium caprate as absorption enhancer reaches therapeutic levels. J Drug Target. 13:573–83.
- Riley, R.G., Green, K.L., Smart, J.D., Tsibouklis, J., Davis, J.A., Hampson, F., Dettmar, P.W., Wilber, W.R. (2001). The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study. Biomaterials. 22:1861–7.
- Sakai, M., Imai, T., Ohtake, H., Otagiri, M. (1998). Cytotoxicity of absorption enhancers in Caco-2 cell monolayers. J Pharm Pharmacol. 50:1101–8.
- Vetter, A., Martien, R., Bernkop-Schnurch, A. (2010). Thiolated polycarbophil as an adjuvant for permeation enhancement in nasal delivery of antisense oligonucleotides. J Pharm Sci. 99:1427–39.
- Wachtel, M., Frei, K., Ehler, E., Fontana, A., Winterhalter, K., Gloor, S.M. (1999). Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci. 112:4347–56.
- Zornoza, T., Cano-Cebrian, M.J., Nalda-Molina, R., Guerri, C., Granero, L., Polache, A. (2004). Assessment and modulation of acamprosate intestinal absorption: comparative studies using in situ, in vitro (CACO-2 cell monolayers) and in vivo models. Eur J Pharm Sci. 22:347–56.