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Drug Delivery Volume 22, 2015 - Issue 1
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Research Article

Improving transfection efficiency of ultrapure oligochitosan/DNA polyplexes by medium acidification

Mireia AgirreNanoBioCel Group, University of the Basque Country, Vitoria-Gasteiz, Spain and ;Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain
,
Jon ZarateNanoBioCel Group, University of the Basque Country, Vitoria-Gasteiz, Spain and ;Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain
,
Gustavo PurasNanoBioCel Group, University of the Basque Country, Vitoria-Gasteiz, Spain and ;Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain
,
Edilberto OjedaNanoBioCel Group, University of the Basque Country, Vitoria-Gasteiz, Spain and ;Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain
&
José Luis PedrazNanoBioCel Group, University of the Basque Country, Vitoria-Gasteiz, Spain and ;Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain Correspondence[email protected].
Pages 100-110 | Received 01 Oct 2013, Accepted 28 Nov 2013, Published online: 28 Jan 2014

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Rana Abu-Huwaij, Adian Alkarawi, Dima Salman & Furqan Alkarawi. (2023) Exploring the use of niosomes in cosmetics for efficient dermal drug delivery. Pharmaceutical Development and Technology 28:7, pages 708-718.
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Zhe Chen, Zhousheng Jin, Yun Xia, Shishi Zhao, Xuzhong Xu, Thomas J. Papadimos & Quanguang Wang. (2017) The protective effect of lipid emulsion in preventing bupivacaine-induced mitochondrial injury and apoptosis of H9C2 cardiomyocytes. Drug Delivery 24:1, pages 430-436.
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Jie Qu, Liangqiao Zhang, Zhihua Chen, Guohua Mao, Ziyun Gao, Xianliang Lai, Xingen Zhu & Jianming Zhu. (2016) Nanostructured lipid carriers, solid lipid nanoparticles, and polymeric nanoparticles: which kind of drug delivery system is better for glioblastoma chemotherapy?. Drug Delivery 23:9, pages 3408-3416.
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Sesha Subramanian Murugan, Se-Kwon Kim, Pandurang Appana Dalavi, Jayachandran Venkatesan & Gi Hun Seong. 2022. Chitooligosaccharides. Chitooligosaccharides 173 183 .
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Myriam Sainz-Ramos, Ilia Villate-Beitia, Idoia Gallego, Nuseibah AL Qtaish, Margarita Menéndez, Laura Lagartera, Santiago Grijalvo, Ramón Eritja, Gustavo Puras & José Luis Pedraz. (2021) Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency. Pharmaceutics 13:11, pages 1787.
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Radostina Kalinova, Miroslava Valchanova, Ivaylo Dimitrov, Sevdalina Turmanova, Iva Ugrinova, Maria Petrova, Zlatina Vlahova & Stanislav Rangelov. (2021) Functional Polyglycidol-Based Block Copolymers for DNA Complexation. International Journal of Molecular Sciences 22:17, pages 9606.
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Eleni Markoutsa, Andrew R. McGill, Anthony Singer, Heta Jadhav, Subhra Mohapatra & Shyam S. Mohapatra. (2021) A multifunctional nanoparticle as a prophylactic and therapeutic approach targeting respiratory syncytial virus. Nanomedicine: Nanotechnology, Biology and Medicine 32, pages 102325.
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Oksana Babii, Zhenggang Wang, Guangyu Liu, Elisa C. Martinez, Sylvia van Drunen Littel-van den Hurk & Lingyun Chen. (2020) Low molecular weight chitosan nanoparticles for CpG oligodeoxynucleotides delivery: Impact of molecular weight, degree of deacetylation, and mannosylation on intracellular uptake and cytokine induction. International Journal of Biological Macromolecules 159, pages 46-56.
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Xiong Xiao, Dapeng Zhang, Mingyu Wang, Wenhui Ling, Chunxia Xiong, Dengfeng Xie, Xinyue Chu, Yunxin Li, Yun Huang, Tong Li, Yuemin Li & Xiaoyan Qiu. (2020) Generation and delivery of “Yamanaka factor” recombinant proteins mediated with magnetic iron oxide nanoparticles (MIONPs). Applied Nanoscience 10:6, pages 1757-1770.
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Nuseibah AL Qtaish, Idoia Gallego, Ilia Villate-Beitia, Myriam Sainz-Ramos, Tania Belén López-Méndez, Santiago Grijalvo, Ramón Eritja, Cristina Soto-Sánchez, Gema Martínez-Navarrete, Eduardo Fernández, Gustavo Puras & José Luis Pedraz. (2020) Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues. Pharmaceutics 12:3, pages 198.
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Jonas Buck, Philip Grossen, Pieter R. Cullis, Jörg Huwyler & Dominik Witzigmann. (2019) Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. ACS Nano 13:4, pages 3754-3782.
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Divya Sharma, Sanjay Arora, Bruna dos Santos Rodrigues, Sushant Lakkadwala, Amrita Banerjee & Jagdish Singh. 2019. Functional Chitosan. Functional Chitosan 229 267 .
Wei-Rong Yang, Ting-Ting Liao, Zi-Qiang Bao, Cai-Quan Zhou, Hong-Yan Luo, Cheng Lu, Min-Hui Pan & Xian-Zhong Wang. (2018) Role of AMPK in the expression of tight junction proteins in heat-treated porcine Sertoli cells. Theriogenology 121, pages 42-52.
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Ilia Villate-Beitia, Gustavo Puras, Cristina Soto-Sánchez, Mireia Agirre, Edilberto Ojeda, Jon Zarate, Eduardo Fernández & José Luis Pedraz. (2017) Non-viral vectors based on magnetoplexes, lipoplexes and polyplexes for VEGF gene delivery into central nervous system cells. International Journal of Pharmaceutics 521:1-2, pages 130-140.
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B. Layek & J. Singh. 2017. Chitosan Based Biomaterials Volume 2. Chitosan Based Biomaterials Volume 2 209 244 .
Ana V. Oliveira, Adriana Marcelo, Ana M. Rosa da Costa & Gabriela A. Silva. (2016) Evaluation of cystamine-modified hyaluronic acid/chitosan polyplex as retinal gene vector. Materials Science and Engineering: C 58, pages 264-272.
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Mireia Agirre, Edilberto Ojeda, Jon Zarate, Gustavo Puras, Santiago Grijalvo, Ramón Eritja, Gontzal García del Caño, Sergio Barrondo, Imanol González-Burguera, Maider López de Jesús, Joan Sallés & José Luis Pedraz. (2015) New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes. Molecular Pharmaceutics 12:11, pages 4056-4066.
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Mireia Agirre, Jon Zarate, Edilberto Ojeda, Gustavo Puras, Luis A. Rojas, Ramón Alemany & José L. Pedraz. (2015) Delivery of an adenovirus vector plasmid by ultrapure oligochitosan based polyplexes. International Journal of Pharmaceutics 479:2, pages 312-319.
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