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Research Article

A novel ligand conjugated nanoparticles for oral insulin delivery

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Pages 2015-2025 | Received 25 Mar 2015, Accepted 01 Jun 2015, Published online: 23 Jul 2015

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Read on this site (4)

Mohammad Reza Fadaei, Marzieh Mohammadi, Mohammad Saleh Fadaei & Mahmoud Reza Jaafari. (2023) The crossroad of nanovesicles and oral delivery of insulin. Expert Opinion on Drug Delivery 20:10, pages 1387-1413.
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Yazid Zaiki, Lee Yong Lim & Tin Wui Wong. (2023) Critical material designs for mucus- and mucosa-penetrating oral insulin nanoparticle development. International Materials Reviews 68:2, pages 121-139.
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Fengling Wang, Lian Li, Wei Sun, Lijia Li, Yuanyuan Liu, Yuan Huang & Zhou Zhou. (2018) A novel αVβ3 ligand-modified HPMA copolymers for anticancer drug delivery. Journal of Drug Targeting 26:3, pages 231-241.
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Zhen Lu, Cuiping Bu, Weicheng Hu, Hui Zhang, Mengrui Liu, Meiqi Lu & Guangxi Zhai. (2018) Preparation and in vitro and in vivo evaluation of quercetin-loaded mixed micelles for oral delivery. Bioscience, Biotechnology, and Biochemistry 82:2, pages 238-246.
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Articles from other publishers (29)

Taoxing Peng, Xinyue Shao, Li Long, Han Liu, Wenqin Song, Jiazhen Hou, Haijun Zhong, Yang Ding & Yongzhuo Huang. (2023) Rational design of oral delivery nanosystems for hypoglycemic peptides. Nano Today 53, pages 102031.
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Haoyang Yuan, Chen Guo, Lei Liu, Linxuan Zhao, Yu Zhang, Tian Yin, Haibing He, Jingxin Gou, Bochen Pan & Xing Tang. (2023) Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides. Carbohydrate Polymers 312, pages 120838.
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Parisa Dehghani, Monireh Esmaeili Rad, Atefeh Zarepour, Ponnurengam Malliappan Sivakumar & Ali Zarrabi. (2023) An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment. Mini-Reviews in Medicinal Chemistry 23:2, pages 192-216.
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Huiwen Pang, Xiangquan Huang, Zhi Ping Xu, Chen Chen & Felicity Y. Han. (2023) Progress in oral insulin delivery by PLGA nanoparticles for the management of diabetes. Drug Discovery Today 28:1, pages 103393.
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Tilahun Ayane Debele & Yoonjee Park. (2022) Application of Nanoparticles: Diagnosis, Therapeutics, and Delivery of Insulin/Anti-Diabetic Drugs to Enhance the Therapeutic Efficacy of Diabetes Mellitus. Life 12:12, pages 2078.
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Céline Cegarra, Béatrice Cameron, Catarina Chaves, Tarik Dabdoubi, Tuan-Minh Do, Bruno Genêt, Valérie Roudières, Yi Shi, Patricia Tchepikoff & Dominique Lesuisse. (2022) An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family. PLOS ONE 17:9, pages e0274667.
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Ji-Yuan Zhang, Xiao-Xia Liu, Jia-Yi Lin, Xiao-Yan Bao, Jian-Qing Peng, Zi-Peng Gong, Xin Luan & Yi Chen. (2022) Biomimetic engineered nanocarriers inspired by viruses for oral-drug delivery. International Journal of Pharmaceutics 624, pages 121979.
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Yuntao Liu, Siqi Zeng, Wei Ji, Huan Yao, Lin Lin, Haiying Cui, Hélder A. Santos & Guoqing Pan. (2021) Emerging Theranostic Nanomaterials in Diabetes and Its Complications. Advanced Science 9:3, pages 2102466.
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Chengyuan Huang, Xuan Zhao, Meiling Su & Zongning Yin. (2021) Construction and evaluation of novel αvβ3 integrin ligand-conjugated ultrasmall star polymer micelles targeted glomerular podocytes through GFB permeation. Biomaterials 276, pages 121053.
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Quangang Zhu, Zhongjian Chen, Pijush Kumar Paul, Yi Lu, Wei Wu & Jianping Qi. (2021) Oral delivery of proteins and peptides: Challenges, status quo and future perspectives. Acta Pharmaceutica Sinica B 11:8, pages 2416-2448.
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Dao Ge Chen, Cheng Wu Zhao, Yan Chun Gong, Zi Ling Li, Yu Ping Li & Xiang Yuan Xiong. (2021) Study on the Influencing Factors of Hypoglycemic Effect of Folate Targeted Polymersomes Encapsulating Insulin. Journal of Pharmaceutical Sciences 110:5, pages 2105-2113.
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Bin Liu, Lulu Jiao, Jingjing Chai, Cheng Bao, Ping Jiang & Yuan Li. 2021. Food Hydrocolloids. Food Hydrocolloids 369 407 .
Feiyang Deng & You Han Bae. (2020) Bile acid transporter-mediated oral drug delivery. Journal of Controlled Release 327, pages 100-116.
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Avaneesh K. Pandey, Nusrat Shafiq, Ritika K. Bhandari, Imraan I.G. Rather, Navjot Kaur, Alka Bhatia, Sadhna Sharma & Samir Malhotra. (2020) Pharmacokinetic and pharmacodynamic evaluation of nano-fixed dose combination for hypertension. Journal of Hypertension 38:8, pages 1593-1602.
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Yining Xu, Neha Shrestha, Véronique Préat & Ana Beloqui. (2020) Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems. Journal of Controlled Release 322, pages 486-508.
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Hiroki Ukai, Kazuki Iwasa, Takamasa Deguchi, Masaki Morishita, Hidemasa Katsumi & Akira Yamamoto. (2020) Enhanced Intestinal Absorption of Insulin by Capryol 90, a Novel Absorption Enhancer in Rats: Implications in Oral Insulin Delivery. Pharmaceutics 12:5, pages 462.
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Ying Liu, Zifei Jiang, Xuefeng Hou, Xingmei Xie, Jiangpei Shi, Junyi Shen, Yuanzhi He, Zhi Wang & Nianping Feng. (2019) Functional lipid polymeric nanoparticles for oral drug delivery: Rapid mucus penetration and improved cell entry and cellular transport. Nanomedicine: Nanotechnology, Biology and Medicine 21, pages 102075.
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Joan Cabellos, Camilla Delpivo, Socorro Vázquez-Campos & Gemma Janer. (2019) In vitro assessment of CeO2 nanoparticles effects on intestinal microvilli morphology. Toxicology in Vitro 59, pages 70-77.
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Pratyusa Sahoo, Kok Hoong Leong, Shaik Nyamathulla, Yoshinori Onuki, Kozo Takayama & Lip Yong Chung. (2019) Chitosan complexed carboxymethylated iota-carrageenan oral insulin particles: Stability, permeability and in vivo evaluation. Materials Today Communications 20, pages 100557.
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Jianyong Jiang, Ke Li, Sergey Komarov, Joseph A. O'Sullivan & Yuan‐Chuan Tai. (2019) Feasibility study of a point‐of‐care positron emission tomography system with interactive imaging capability. Medical Physics 46:4, pages 1798-1813.
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Wenji Deng, Huan Wang, Baojian Wu & Xingwang Zhang. (2019) Selenium-layered nanoparticles serving for oral delivery of phytomedicines with hypoglycemic activity to synergistically potentiate the antidiabetic effect. Acta Pharmaceutica Sinica B 9:1, pages 74-86.
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Qiaobin Hu & Yangchao Luo. (2018) Recent advances of polysaccharide-based nanoparticles for oral insulin delivery. International Journal of Biological Macromolecules 120, pages 775-782.
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Jingjing Chai, Ping Jiang, Pengjie Wang, Yumeng Jiang, Dan Li, Weier Bao, Bingxue Liu, Bin Liu, Liyun Zhao, Willem Norde, Qipeng Yuan, Fazheng Ren & Yuan Li. (2018) The intelligent delivery systems for bioactive compounds in foods: Physicochemical and physiological conditions, absorption mechanisms, obstacles and responsive strategies. Trends in Food Science & Technology 78, pages 144-154.
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Yining Xu, Yaxian Zheng, Lei Wu, Xi Zhu, Zhirong Zhang & Yuan Huang. (2018) Novel Solid Lipid Nanoparticle with Endosomal Escape Function for Oral Delivery of Insulin. ACS Applied Materials & Interfaces 10:11, pages 9315-9324.
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Min Liu, Lei Wu, Wei Shan, Yi Cui & Yuan Huang. (2018) Iron-mimic peptide converts transferrin from foe to friend for orally targeting insulin delivery. Journal of Materials Chemistry B 6:4, pages 593-601.
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Lian Li, Minglu Zhou & Yuan Huang. (2018) Synergistic enhancement of anticancer therapeutic efficacy of HPMA copolymer doxorubicin conjugates via combination of ligand modification and stimuli-response srategies. International Journal of Pharmaceutics 536:1, pages 450-458.
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Ali Mousavizadeh, Ali Jabbari, Mohammad Akrami & Hassan Bardania. (2017) Cell targeting peptides as smart ligands for targeting of therapeutic or diagnostic agents: a systematic review. Colloids and Surfaces B: Biointerfaces 158, pages 507-517.
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Wenji Deng, Qian Xie, Huan Wang, Zhiguo Ma, Baojian Wu & Xingwang Zhang. (2017) Selenium nanoparticles as versatile carriers for oral delivery of insulin: Insight into the synergic antidiabetic effect and mechanism. Nanomedicine: Nanotechnology, Biology and Medicine 13:6, pages 1965-1974.
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Joan Cabellos, Camilla Delpivo, Elisabet Fernández-Rosas, Socorro Vázquez-Campos & Gemma Janer. (2017) Contribution of M-cells and other experimental variables in the translocation of TiO2 nanoparticles across in vitro intestinal models. NanoImpact 5, pages 51-60.
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