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Original Article

Dose Response Effect of Diaspirin Crosslinked Hemoglobin (DCLHb) on Systemic Hemodynamics and Regional Blood Circulation in Rats

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Pages 75-84 | Published online: 11 Jul 2009

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Armin Schubert, Jerome F. O'Hara, Robert J. Przybelski, John E. Tetzlaff, Kenneth E. Marks, Edward Mascha & Andrew C. Novick. (2002) EFFECT OF DIASPIRIN CROSSLINKED HEMOGLOBIN (DCLHb HemAssist™) DURING HIGH BLOOD LOSS SURGERY ON SELECTED INDICES OF ORGAN FUNCTION *. Artificial Cells, Blood Substitutes, and Biotechnology 30:4, pages 259-283.
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Guy Rosenthal, Diane Morabito, Mitchell Cohen, Annina Roeytenberg, Nikita Derugin, S. Scott Panter, M. Margaret Knudson & Geoffrey Manley. (2008) Use of hemoglobin-based oxygen-carrying solution–201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage. Journal of Neurosurgery 108:3, pages 575-587.
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Hae W. Kim & A. Gerson Greenburg. 2005. Oxygen Transport to Tissue XXVI. Oxygen Transport to Tissue XXVI 397 401 .
Mat van Iterson, Martin Siegemund, Kenneth Burhop & Can Ince. (2003) Hemoglobin-Based Oxygen Carrier Provides Heterogeneous Microvascular Oxygenation in Heart and Gut after Hemorrhage in Pigs. The Journal of Trauma: Injury, Infection, and Critical Care 55:6, pages 1111-1124.
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Thomas C. Resta, Benjimen R. Walker, Mark R. Eichinger & Michael P. Doyle. (2002) Rate of NO scavenging alters effects of recombinant hemoglobin solutions on pulmonary vasoreactivity. Journal of Applied Physiology 93:4, pages 1327-1336.
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R. Ferrera, G. Hadour, P. Chiari, P. Montagna, O. Jegaden, K. Burhop & J. J. Lehot. (2002) Effect of diaspirin cross-linked haemoglobin (DCLHbtm) on mean arterial pressure during cardiopulmonary bypass in swine. Transfusion Medicine 12:5, pages 311-316.
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Ronald Kluger. (2002) 2001 Lemieux Award Lecture Organic chemistry and hemoglobin: Benefits from controlled alteration. Canadian Journal of Chemistry 80:3, pages 217-221.
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Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
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Armin Schubert. (2001) Hemoglobin-based oxygen carriers, blood substitutes, and their relevance to high-volume blood loss. Seminars in Anesthesia, Perioperative Medicine and Pain 20:1, pages 78-84.
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Mark R. Forrest, Adrian H. Chester & David Royston. (2001) The Effects of Diaspirin Cross-Linked Hemoglobin on the Tone of Human Saphenous Vein. Anesthesia & Analgesia 92:2, pages 324-328.
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Mark R. Forrest, Adrian H. Chester & David Royston. (2001) The Effects of Diaspirin Cross-Linked Hemoglobin on the Tone of Human Saphenous Vein. Anesthesia and Analgesia, pages 324-328.
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Robert M. Winslow. (2000) alphaalpha-Crosslinked Hemoglobin: Was Failure Predicted by Preclinical Testing?. Vox Sanguinis 79:1, pages 1-20.
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Rameshraja Palaparthy, Huashan Wang & Anil Gulati. (2000) Current aspects in pharmacology of modified hemoglobins. Advanced Drug Delivery Reviews 40:3, pages 185-198.
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Anil Gulati, Abhijit Barve & Ananda P. Sen. (1999) Pharmacology of hemoglobin therapeutics. Journal of Laboratory and Clinical Medicine 133:2, pages 112-119.
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Michael P. Doyle, Izydor Apostol & Bruce A. Kerwin. (1999) Glutaraldehyde Modification of Recombinant Human Hemoglobin Alters Its Hemodynamic Properties. Journal of Biological Chemistry 274:4, pages 2583-2591.
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Mark S. Crago, Shanda D. West & Jack E. McKenzie. (1999) Effects of diaspirin crosslinked hemoglobin infusion in treadmill-exercised swine. Heart and Vessels 14:1, pages 1-8.
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T. Frietsch, C. Lenz & K. F. Waschke. (1998) Artificial oxygen carriers. European Journal of Anaesthesiology 15:5, pages 571-584.
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