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Pharmaceutical Development and Technology Volume 20, 2015 - Issue 3
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Research Article

Formulation and evaluation of cholesterol-rich nanoemulsion (LDE) for drug delivery potential of cholesteryl-maleoyl-5-fluorouracil

Fars K. AlanaziKayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia and
,
Nazrul HaqKayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia and ;Center of Excellence in Biotechnology Research (CEBR), Riyadh, Saudi Arabia
,
Awwad A. RadwanKayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia and
,
Ibrahim A. AlsarraKayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia and ;Center of Excellence in Biotechnology Research (CEBR), Riyadh, Saudi Arabia
&
Faiyaz ShakeelKayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia and ;Center of Excellence in Biotechnology Research (CEBR), Riyadh, Saudi ArabiaCorrespondence[email protected]
Pages 266-270 | Received 17 Sep 2013, Accepted 07 Oct 2013, Published online: 25 Nov 2013

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Saleh A. Alanazi, Gamaleldin I. Harisa, Mohamed M. Badran, Fars K. Alanazi, Ehab Elzayat, Abdullah H. Alomrani, Osaid T. Al Meanazel & Ahmed T. Al Meanazel. (2021) Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition. Bioengineered 12:1, pages 914-926.
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Ashish Garg, Vaibhav Patel, Rajeev Sharma, Amit Jain & Awesh K. Yadav. (2017) Heparin-appended polycaprolactone core/corona nanoparticles for site specific delivery of 5-fluorouracil. Artificial Cells, Nanomedicine, and Biotechnology 45:6, pages 1146-1155.
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Articles from other publishers (8)

Niyaz Ahmad, Ahmed A. Albassam, Mohd Faiyaz Khan, Zabih Ullah, Taysser Mohammed Buheazah, Hussain Salman AlHomoud & Hassan Ali Al-Nasif. (2022) A novel 5-Fluorocuracil multiple-nanoemulsion used for the enhancement of oral bioavailability in the treatment of colorectal cancer. Saudi Journal of Biological Sciences 29:5, pages 3704-3716.
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Nourhan A. Abdulla, Gehan F. Balata, Hanaa A. El-ghamry & Eman Gomaa. (2021) Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement. Saudi Pharmaceutical Journal 29:12, pages 1466-1485.
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Laila J. Alhadad, Gamaleldin I. Harisa & Fars K. Alanazi. (2020) Design and encapsulation of anticancer dual HSP27 and HER2 inhibitor into low density lipoprotein to target ovarian cancer cells. Saudi Pharmaceutical Journal 28:4, pages 387-396.
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Josef Jampílek & Katarína Kráľová. 2019. Nanoarchitectonics in Biomedicine. Nanoarchitectonics in Biomedicine 219 294 .
Faiyaz Shakeel, Nazrul Haq, Mohammad Raish, Nasir A. Siddiqui, Fars K. Alanazi & Ibrahim A. Alsarra. (2016) Antioxidant and cytotoxic effects of vanillin via eucalyptus oil containing self-nanoemulsifying drug delivery system. Journal of Molecular Liquids 218, pages 233-239.
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Faiyaz Shakeel, Muzaffar Iqbal & Essam Ezzeldin. (2016) Bioavailability enhancement and pharmacokinetic profile of an anticancer drug ibrutinib by self-nanoemulsifying drug delivery system. Journal of Pharmacy and Pharmacology 68:6, pages 772-780.
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Faiyaz Shakeel, Fars K. Alanazi, Mohammad Raish, Nazrul Haq, Awwad A. Radwan & Ibrahim A. Alsarra. (2015) Pharmacokinetic and in vitro cytotoxic evaluation of cholesterol-rich nanoemulsion of cholesteryl-succinyl-5-fluorouracil. Journal of Molecular Liquids 211, pages 164-168.
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Mashooq A. Bhat, Muzaffar Iqbal, Abdullah Al-Dhfyan & Faiyaz Shakeel. (2015) Carvone Schiff base of isoniazid as a novel antitumor agent: Nanoemulsion development and pharmacokinetic evaluation. Journal of Molecular Liquids 203, pages 111-119.
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