Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 20, 2015 - Issue 6
Submit an article Journal homepage
165
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Statistical optimization of controlled release microspheres containing cetirizine hydrochloride as a model for water soluble drugs

Khalid M. El-SayDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA, ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt, Correspondence[email protected] [email protected] [email protected]
,
Abdel-Rahim M. El-HelwDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA,
,
Osama A. A. AhmedDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA, ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia, Egypt, and
,
Khaled M. HosnyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA, ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni Sueif University, Beni Suef, Egypt
,
Tarek A. AhmedDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA, ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt,
,
Rasha M. KharshoumDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni Sueif University, Beni Suef, Egypt
,
Usama A. FahmyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA,
&
Majed AlsawahliDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA,
show all
Pages 738-746 | Received 14 Jan 2014, Accepted 16 Apr 2014, Published online: 26 May 2014

Citations (17)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

Saeed A. S. Al-Zuhairy, Mahmoud H. Teaima, Nabil A. Shoman, Mohamed Elasaly, Mohamed A. El-Nabarawi & Hossam S. El-Sawy. (2023) PEGylated Tween 80-functionalized chitosan-lipidic nano-vesicular hybrids for heightening nose-to-brain delivery and bioavailability of metoclopramide. Drug Delivery 30:1.
Read now
Mohamed H. Desoqi, Hossam S. El-Sawy, Elsayed Kafagy, Mamdouh Ghorab & Shadeed Gad. (2021) Fluticasone propionate–loaded solid lipid nanoparticles with augmented anti-inflammatory activity: optimisation, characterisation and pharmacodynamic evaluation on rats. Journal of Microencapsulation 38:3, pages 177-191.
Read now
Osama AA Ahmed, Khalid M El-Say, Bader M Aljaeid, Shaimaa M Badr-Eldin & Tarek A Ahmed. (2019) Optimized vinpocetine-loaded vitamin E D-α-tocopherol polyethylene glycol 1000 succinate-alpha lipoic acid micelles as a potential transdermal drug delivery system: in vitro and ex vivo studies. International Journal of Nanomedicine 14, pages 33-43.
Read now
Bader M. Aljaeid, Khalid M. El-Say & Khaled M. Hosny. (2019) Chitosan-TPP nanoparticles stabilized by poloxamer for controlling the release and enhancing the bioavailability of doxazosin mesylate: in vitro, and in vivo evaluation. Drug Development and Industrial Pharmacy 45:7, pages 1130-1139.
Read now
Noha M Badawi, Mahmoud H Teaima, Khalid M El-Say, Dalia A Attia, Mohamed A El-Nabarawi & Mohey M Elmazar. (2018) Pomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study. International Journal of Nanomedicine 13, pages 1313-1326.
Read now
Tarek A Ahmed. (2016) Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation. International Journal of Nanomedicine 11, pages 515-527.
Read now
Khalid Mohamed El-Say. (2016) Maximizing the encapsulation efficiency and the bioavailability of controlled-release cetirizine microspheres using Draper–Lin small composite design. Drug Design, Development and Therapy 10, pages 825-839.
Read now

Articles from other publishers (10)

Prasanta K. Mohapatra & Sunit K. Sahoo. (2023) EFFECT OF PREPARATION TEMPERATURE ON ETHYLCELLULOSE MICROSPHERE PROPERTIES PREPARED BY OIL-IN-OIL EMULSION SOLVENT EVAPORATION PROCESS. Indian Drugs 60:05, pages 29-41.
Crossref
Alshaimaa M. Almehmady, Khalid M. El-Say, Manal A. Mubarak, Haneen A. Alghamdi, Njood A. Somali, Alaa Sirwi, Rahmah Algarni & Tarek A. Ahmed. (2022) Enhancing the Antifungal Activity and Ophthalmic Transport of Fluconazole from PEGylated Polycaprolactone Loaded Nanoparticles. Polymers 15:1, pages 209.
Crossref
Mohamed F. Zaky, Mohamed A. Megahed, Taha M. Hammady, Shadeed Gad, Mamdouh Mostafa Ghorab & Khalid M. El-Say. (2022) Tailoring Apixaban in Nanostructured Lipid Carrier Enhancing Its Oral Bioavailability and Anticoagulant Activity. Pharmaceutics 15:1, pages 80.
Crossref
Nabil A. Alhakamy, Khaled M. Hosny, Ahmed Y. Aldryhim, Waleed Y. Rizg, Bayan A. Eshmawi, Haitham A. Bukhary, Samar S.A. Murshid & Rasha A. Khallaf. (2022) Development and optimization of ofloxacin as solid lipid nanoparticles for enhancement of its ocular activity. Journal of Drug Delivery Science and Technology 72, pages 103373.
Crossref
Omar D. Al-hejaili, Abdullah A. Alamoudi, Osama A. A. Ahmed & Khalid M. El-Say. (2022) Transdermal Film Loaded with Avanafil Ultra-deformable Nanovesicles to Enhance its Percutaneous Absorption and Bioavailability. AAPS PharmSciTech 23:1.
Crossref
Mohamed A. Ali, Magdy I. Mohamed, Mohamed A. Megahed, Tamer M. Abdelghany & Khalid M. El-Say. (2021) Cholesterol-Based Nanovesicles Enhance the In Vitro Cytotoxicity, Ex Vivo Intestinal Absorption, and In Vivo Bioavailability of Flutamide. Pharmaceutics 13:11, pages 1741.
Crossref
Yamin Zhao, Lujun Zhang, Xiaoxue Zhai, Qian Liu, Lebing Sun, Mengshi Liu, Lili An, Liang Xian, Ping Zhang & Lihua Chen. (2021) Study on Adsorption Performance of Benzoic Acid in Cyclocarya paliurus Extract by Ethyl Cellulose Microspheres. Chemistry 3:4, pages 1113-1125.
Crossref
Ayan Kumar Kar, Arijit Shil, Banhishikha Kar & Sanjay Dey. (2020) Formulation development and statistical optimization of zingiberol incorporated sodium alginate-methyl cellulose blend microspheres. International Journal of Biological Macromolecules 162, pages 1578-1586.
Crossref
Mohamed Fouad Radwan, Mohamed Ahmed El- Moselhy, Usama Ahmed Fahmy & Bader Mubarak Aljaeid. (2019) Novel Combination of Alprostadil-D-tocopheryl Polyethylene Glycol Succinate for Treatment of Erectile Dysfunction. International Journal of Pharmacology 15:6, pages 738-744.
Crossref
Khalid Mohamed El-Say & Khaled Mohamed Hosny. (2018) Optimization of carvedilol solid lipid nanoparticles: An approach to control the release and enhance the oral bioavailability on rabbits. PLOS ONE 13:8, pages e0203405.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.