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Research Article

Effectiveness of Morphine, Fentanyl, and Methoxyflurane in the Prehospital Setting

, MBBS, M Med (Clin EPI), , BHSc, BEd, , BHA, , , PhD & , MBBS, M Med (Clin EPI), PhD
Pages 439-447 | Received 13 Oct 2009, Accepted 07 Apr 2010, Published online: 01 Sep 2010

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Read on this site (9)

Alexander Egger, Tobias Huber, Stefan Heschl, Jakob Fiegl, Josef Burger, Helmut Trimmel, Wolfgang Schreiber, Maximilian Niederer, Katharina Tscherny & Dominik Roth. (2023) Efficacy and Safety of Methoxyflurane for Treatment of Acute Traumatic Pain by EMTs during Alpine Rescue Operations: The “PainDrop” Trial. Prehospital Emergency Care 27:8, pages 987-992.
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Antonio Voza, Germana Ruggiano, Sossio Serra, Giuseppe Carpinteri, Gianfilippo Gangitano, Fabio Intelligente, Elisabetta Bonafede, Antonella Sblendido, Alberto Farina, Amedeo Soldi & Andrea Fabbri. (2020) Inhaled Methoxyflurane versus Intravenous Morphine for Severe Trauma Pain in the Emergency Setting: Subgroup Analysis of MEDITA, a Multicenter, Randomized, Controlled, Open-Label Trial. Journal of Pain Research 13, pages 491-502.
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Keith M Porter, Anthony D Dayan, Sara Dickerson & Paul M Middleton. (2018) The role of inhaled methoxyflurane in acute pain management. Open Access Emergency Medicine 10, pages 149-164.
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Johann Lebon, Francis Fournier, François Bégin, Denise Hebert, Richard Fleet, Guilaume Foldes-Busque & Alain Tanguay. (2016) Subcutaneous Fentanyl Administration: A Novel Approach for Pain Management in a Rural and Suburban Prehospital Setting. Prehospital Emergency Care 20:5, pages 648-656.
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Robert T. Gerhardt, Patrick T. Reeves, Russ S. Kotwal, Robert L. Mabry, John B. Robinson & Frank Butler. (2016) Analysis of Prehospital Documentation of Injury-Related Pain Assessment and Analgesic Administration on the Contemporary Battlefield. Prehospital Emergency Care 20:1, pages 37-44.
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Marianne Gausche-Hill, Kathleen M. Brown, Zoë J. Oliver, Comilla Sasson, Peter S. Dayan, Nicholas M. Eschmann, Tasmeen S. Weik, Benjamin J. Lawner, Ritu Sahni, Yngve Falck-Ytter, Joseph L. Wright, Knox Todd & Eddy S. Lang. (2014) An Evidence-based Guideline for Prehospital Analgesia in Trauma. Prehospital Emergency Care 18:sup1, pages 25-34.
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Paul M. Simpson, Bernadette McCabe, Jason C. Bendall, David C. Cone & Paul M. Middleton. (2012) Paramedic-Performed Digital Nerve Block To Facilitate Field Reduction Of A Dislocated Finger. Prehospital Emergency Care 16:3, pages 415-417.
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Brandon K. Bellows & Joseph Biskupiak. (2011) Methodological Challenges of Comparative Effectiveness Research in Pain: Implications for Investigators, Clinicians, and Policy Makers. Journal of Pain & Palliative Care Pharmacotherapy 25:3, pages 267-274.
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Jason C. Bendall, Paul M. Simpson & Paul M. Middleton. (2011) Effectiveness of Prehospital Morphine, Fentanyl, and Methoxyflurane in Pediatric Patients. Prehospital Emergency Care 15:2, pages 158-165.
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Murray D. Smith, Elise Rowan, Robert Spaight & Aloysius N. Siriwardena. (2022) Evaluation of the effectiveness and costs of inhaled methoxyflurane versus usual analgesia for prehospital injury and trauma: non-randomised clinical study. BMC Emergency Medicine 22:1.
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Tierra V. Lynch, Peter W. Callas, Timothy D. Peterson & Sarah M. Schlein. (2022) Intranasal Fentanyl for On-the-Hill Analgesia by Ski Patrol. Wilderness & Environmental Medicine 33:3, pages 296-303.
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Owen D Williams & Graham Pluck. (2019) The use of methoxyflurane (Penthrox®) for procedural analgesia in the emergency department and pre-hospital environment. Trauma 22:2, pages 85-93.
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Alberto M. Borobia, Sergio García Collado, César Carballo Cardona, Rosa Capilla Pueyo, Cesáreo Fernández Alonso, Ignacio Pérez Torres, María Corell González, José Ramón Casal Codesido, María Arranz Betegón, Luis Amador Barcela, Aitor Odiaga Andicoechea, Anselma Fernández Testa, Jorge Trigo Colina, Antonio Cid Dorribo, Carmen del Arco Galán, Jose Carlos Martínez Ávila, Susana Traseira Lugilde, Antonio J. Carcas Sansuán, Claudio Bueno Marisca, Pedro Mesa Rodríguez, Emilio Montero Romero, José Lázaro González, María A. Jañez Álvarez, Roberto Rodríguez Alonso, Javier del Castillo Nos, Manuel V. Duran Ruiz, Pere Llorens Soriano, Wilkins Poy, Luis Sanchez Santos, Fátima Barcala del Caño, Ángela Dopico García, Paula Núñez Gaviño, Elena Sánchez Fernández Linares, Jose Valle Cruz, Norma B. Sanz Cadenas, Maite Ayuso Aragonés, Lubna Dani, Olga González Peña, María M. Jaén Cañadas, Mikel Rico Briñas, Yale Tung Cheng, Isabel López Isidro, Laura Ferrer Armengou, Paula Molina Ávila, Amaia Etxebarria Gulías, Kristina García Lombardía & Patricia Wunderling Brüggenmann. (2020) Inhaled Methoxyflurane Provides Greater Analgesia and Faster Onset of Action Versus Standard Analgesia in Patients With Trauma Pain: InMEDIATE: A Randomized Controlled Trial in Emergency Departments. Annals of Emergency Medicine 75:3, pages 315-328.
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Kristian D. Friesgaard, Hans Kirkegaard, Claus-Henrik Rasmussen, Matthias Giebner, Erika F. Christensen & Lone Nikolajsen. (2019) Prehospital intravenous fentanyl administered by ambulance personnel: a cluster-randomised comparison of two treatment protocols. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 27:1.
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Ayesha Zia, Russell MacDonald, Sean Moore, James Ducharme & Christian Vaillancourt. (2019) Assessment of Pain Management During Interfacility Air Medical Transport of Intubated Patients. Air Medical Journal 38:6, pages 421-425.
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Shah Mizanur Rahman & Eimhear Quinn. (2019) BET 1: Green or blue for you? Methoxyflurane (Penthrox) or nitrous oxide/oxygen 50% mixture (Entonox) for the management of acute pain in the ED. Emergency Medicine Journal 36:8, pages 506-508.
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Stuart Hartshorn & Paul M Middleton. (2018) Efficacy and safety of inhaled low-dose methoxyflurane for acute paediatric pain: A systematic review. Trauma 21:2, pages 94-102.
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Andrea Fabbri, Giuseppe Carpinteri, Germana Ruggiano, Elisabetta Bonafede, Antonella Sblendido, Alberto Farina, Amedeo Soldi, Germana Ruggiano, Isabella Bartoli, Giuseppe Carpinteri, Andrea Fabbri, Francesco Bermano, Maurizio Chiesa, Daniela Mura, Mario Oppes, Peppino Masciari, Davide Torti, Vittorio Iorno, Antonio Voza, Piero Paolini, Sossio Serra, Gianfilippo Gangitano & Raffaella Francesconi. (2018) Methoxyflurane Versus Standard of Care for Acute Trauma-Related Pain in the Emergency Setting: Protocol for a Randomised, Controlled Study in Italy (MEDITA). Advances in Therapy 36:1, pages 244-256.
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K. D. Friesgaard, L. Nikolajsen, M. Giebner, C.‐H. Rasmussen, I. S. Riddervold, H. Kirkegaard & E. F. Christensen. (2015) Efficacy and safety of intravenous fentanyl administered by ambulance personnel. Acta Anaesthesiologica Scandinavica 60:4, pages 537-543.
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