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Original Article

Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

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Pages 547-553 | Received 17 Jun 2009, Accepted 07 Aug 2009, Published online: 14 Dec 2009

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Akanksha Vishwakarma & Digvijay Verma. (2021) Microorganisms: crucial players of smokeless tobacco for several health attributes. Applied Microbiology and Biotechnology 105:16-17, pages 6123-6132.
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Lucas V.L. Martoni, Marina Baccarin, Éder T.G. Cavalheiro & Rafael M. Buoro. (2020) Electrochemical behavior of N-Nitrosodiphenylamine and its determination in synthetic urine samples using a graphite-polyurethane composite electrode. Journal of Electroanalytical Chemistry 857, pages 113747.
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Paweł Kubica. (2019) Ultrasound-Assisted Solvent Extraction of a Porous Membrane Packed Sample for the Determination of Tobacco-Specific Nitrosamines in the Replacement Liquids for E-Cigarettes. Molecules 24:24, pages 4618.
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G. Scherer, G. Gilch, D. Köhler, W. Völkel, T. Göen & A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 2442 2468 .
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Raúl Pérez-Ortuño, Jose M. Martínez-Sánchez, Marcela Fu, Montse Ballbè, Núria Quirós, Esteve Fernández & José A. Pascual. (2016) Assessment of tobacco specific nitrosamines (TSNAs) in oral fluid as biomarkers of cancer risk: A population-based study. Environmental Research 151, pages 635-641.
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Raúl Pérez-Ortuño, Jose M. Martínez-Sánchez, Marcela Fu, Esteve Fernández & José A. Pascual. (2016) Evaluation of tobacco specific nitrosamines exposure by quantification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human hair of non-smokers. Scientific Reports 6:1.
Crossref
Jie Zhang, Ruoshi Bai, Xiaoli Yi, Zhendong Yang, Xingyu Liu, Jun Zhou & Wei Liang. (2016) Fully automated analysis of four tobacco-specific N-nitrosamines in mainstream cigarette smoke using two-dimensional online solid phase extraction combined with liquid chromatography–tandem mass spectrometry. Talanta 146, pages 216-224.
Crossref
Delshanee Kotandeniya, Steven G. Carmella, Makenzie E. Pillsbury & Stephen S. Hecht. (2015) Combined analysis of N′-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in the urine of cigarette smokers and e-cigarette users. Journal of Chromatography B 1007, pages 121-126.
Crossref
P. Upadhyaya & S. S. Hecht. (2014) Quantitative Analysis of 3'-Hydroxynorcotinine in Human Urine. Nicotine & Tobacco Research 17:5, pages 524-529.
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George R. Krautter, Peter X. Chen & Michael F. Borgerding. (2015) Consumption patterns and biomarkers of exposure in cigarette smokers switched to Snus, various dissolvable tobacco products, Dual use, or tobacco abstinence. Regulatory Toxicology and Pharmacology 71:2, pages 186-197.
Crossref
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Jun-Young Yang, Hyun-Kyong Ahn, Si-Won Lee, You-Jung Han, Young-Jun Oh, E. Yadira Velázquez-Armenta & Alejandro A. Nava-Ocampo. (2015) Simple high-throughput analytical method using ultra-performance liquid chromatography coupled with tandem mass spectrometry to quantify total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine. Clinical Chemistry and Laboratory Medicine (CCLM) 53:8.
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Stephen S. Hecht. (2014) It Is Time to Regulate Carcinogenic Tobacco-Specific Nitrosamines in Cigarette Tobacco. Cancer Prevention Research 7:7, pages 639-647.
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Baoyun Xia, Yang Xia, Joshua Wong, Keegan J. Nicodemus, Meng Xu, John Lee, Tonya Guillot & James Li. (2014) Quantitative analysis of five tobacco-specific N -nitrosamines in urine by liquid chromatography-atmospheric pressure ionization tandem mass spectrometry . Biomedical Chromatography 28:3, pages 375-384.
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Jens Schubert, Jürgen Hahn, Gerhard Dettbarn, Albrecht Seidel, Andreas Luch & Thomas G. Schulz. (2011) Mainstream smoke of the waterpipe: Does this environmental matrix reveal as significant source of toxic compounds?. Toxicology Letters 205:3, pages 279-284.
Crossref
Showket H. Bhat, Stacy L. Gelhaus, Clementina Mesaros, Anil Vachani & Ian A. Blair. (2010) A new liquid chromatography/mass spectrometry method for 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) in urine. Rapid Communications in Mass Spectrometry 25:1, pages 115-121.
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David Smith & Patrik Španěl. (2011) Ambient analysis of trace compounds in gaseous media by SIFT-MS. The Analyst 136:10, pages 2009.
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Stephen S. Hecht, Jian-Min Yuan & Dorothy Hatsukami. (2010) Applying Tobacco Carcinogen and Toxicant Biomarkers in Product Regulation and Cancer Prevention. Chemical Research in Toxicology 23:6, pages 1001-1008.
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Lisa A. Peterson. (2010) Formation, Repair, and Genotoxic Properties of Bulky DNA Adducts Formed from Tobacco-Specific Nitrosamines. Journal of Nucleic Acids 2010, pages 1-11.
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